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Full-Text Articles in Medicine and Health Sciences

Fact Or Myth: The Flu Can Be Caused By The Flu Vaccine, Arleigh Wood Apr 2020

Fact Or Myth: The Flu Can Be Caused By The Flu Vaccine, Arleigh Wood

2020 Virtual Spring Student Showcase for Research and Creative Inquiry

To many, the flu vaccine seems like a threat to an otherwise healthy individual. People often get the flu after receiving the flu shot, which does not promote confidence in the general public. These and other reasonings have created a myth that the flu vaccine can cause the flu. Understanding how the vaccination is created and how it interacts with the immune system helps to realize why the flu vaccine cannot cause the virus. For the vaccine to work, adaptive immunity must be activated by the introduction of the viral particles in a safe manner. An effective immune response from …


Kins 499 Mouthguard Use On Throwing Velocity, Nathan Iskowitz, Jo Morrison, Robert Blaisdell Apr 2020

Kins 499 Mouthguard Use On Throwing Velocity, Nathan Iskowitz, Jo Morrison, Robert Blaisdell

2020 Virtual Spring Student Showcase for Research and Creative Inquiry

Successful pitching in baseball may be due to several factors including the mechanics of the motion, the strength, power, flexibility of the athlete, as well as their intent and fatigue levels. The pitching motion is a very powerful, violent, complex and abnormal range of motion of the body. In recent studies, it has been widely evidenced that the ability to produce instantaneous high peak force outputs is related to success in sport. Therefore, the ability to produce higher peak force may be related to the ability to pitching in baseball. Mouthguards have been shown to significantly increase power production in …


Determining The Effects Of Cancer Mutations On The Coactivator Function Of The P300 Core Domain In Human Cells, Katlyn Myers, Erin Shanle, Meagan St. John Apr 2018

Determining The Effects Of Cancer Mutations On The Coactivator Function Of The P300 Core Domain In Human Cells, Katlyn Myers, Erin Shanle, Meagan St. John

Selected Publications

In human cells, DNA is packed into chromosomes by wrapping around proteins called histones. Histone proteins contain chains of amino acids called histone tails and can be modified by acetylation. Acetylating histone proteins is important to the cell because it opens up the chromatin and allows for gene expression. Proteins can recognize and bind histone acetylation with a region called a bromodomain. p300 is a bromodomain-containing protein with histone acetyltransferase activity (HAT) which also aids with gene expression and is a coactivator protein of transcription. The bromodomain and HAT domain of this protein is considered the p300 core. Previous research …