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Full-Text Articles in Medicine and Health Sciences
Impact Of Basal Diet On Obesity Phenotype Of Recipient Mice Following Fecal Microbiome Transfer From Obese Or Lean Human Donors, Daphne Michelle Rodriguez Jimenez
Impact Of Basal Diet On Obesity Phenotype Of Recipient Mice Following Fecal Microbiome Transfer From Obese Or Lean Human Donors, Daphne Michelle Rodriguez Jimenez
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The composition of the gut microbiome can be affected by environmental factors, such as diet. The Western dietary pattern is associated with microbiome dysbiosis and adverse health outcomes, including obesity and metabolic disorders. The objective of this study was to examine the effect of gut microbiota from lean or obese human donors on metabolism and weight gain in recipient mice fed one of three basal diets: 1) the standard AIN93G diet, which promotes rodent health; 2) the total Western diet (TWD), which mimics the American dietary pattern and promotes inflammation-associated colorectal carcinogenesis; and 3) a 45% high fat diet-induced obesity …
Evaluation Of Oocyte Developmental Competence And Potential Strategies To Improve Oocyte Quality, Min Yang
Evaluation Of Oocyte Developmental Competence And Potential Strategies To Improve Oocyte Quality, Min Yang
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Assisted reproductive technologies (ARTs) have now been extensively used to promote reproductive efficiency as a fertility treatment not only in human medicine but also animal reproduction. ARTs serve as an important tool to advance the fundamental knowledge of reproductive processes. The quality of female’s eggs defines its ability to undergo maturation, fertilization, and development. This quality is determined by various factors and is crucial for the success of ARTs. Any alternations happening during the egg growth and maturation process can result in the decreased quality, which could have long-lasting effects on development. Improving the developmental efficiency of the egg is …
Bovine Mastitis Resistance: Novel Quantitative Trait Loci And The Role Of Bovine Mammary Epithelial Cells, Jacqueline P. Kurz
Bovine Mastitis Resistance: Novel Quantitative Trait Loci And The Role Of Bovine Mammary Epithelial Cells, Jacqueline P. Kurz
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Bovine mastitis, or inflammation of the mammary gland, has substantial economic and animal welfare implications. A genetic basis for mastitis resistance traits is recognized and can be used to guide selective breeding programs. The discovery of regions of the genome associated with mastitis resistance, and knowledge of the underlying molecular mechanisms responsible, can facilitate development of efficient mastitis control and therapeutic strategies. The objectives of this dissertation research were to identify sites of genetic variation associated with mastitis resistance, and to define the contributions of the milk-secreting epithelial cells to mammary gland immune responses and mastitis resistance. Twenty seven regions …