Medicine and Health Sciences Commons^™

Recovery Capital, Mental Health And Substance Use Among Individuals Initiating Office-Based Buprenorphine Treatment For Opioid Use Disorder, Hannah R. Callahan, Karen Dugosh, Emily Hurstak, Patty Mccarthy, Emily Garber, Daniel Dejoseph, Julia Dejoseph, Michelle R. Lent

The Journal of Integrated Primary Care

Recovery capital refers to the internal and external resources available to support an individual in their recovery from substance use disorders. Using data from an ongoing trial, the current study examined recovery capital among 225 individuals initiating office-based buprenorphine treatment for opioid use disorder (OUD) at Federally Qualified Health Centers in the mid-Atlantic region. At baseline, participants completed the Brief Assessment of Recovery Capital-10 (BARC-10), a validated measure assessing the 4 major domains of recovery capital and completed a urine toxicology screening. Participants reported BARC-10 scores of 49.22 on average (SD = 8.14). Average scores were highest for the …

Prevalence And Predictors Of Suicidality Among Adults Initiating Office-Based Buprenorphine., Michelle R. Lent, Karen L Dugosh, Emily Hurstak, Hannah R. Callahan, Kimberly Mazur, Greater Philadelphia Opioid Use Disorder Research Group

PCOM Scholarly Papers

BACKGROUND: Individuals who have substance use disorders may have an elevated risk of suicidality. This study sought to examine the prevalence of, and identify factors associated with, suicidality in adults with opioid use disorder (OUD) initiating office-based buprenorphine treatment.

METHODS: Individuals were eligible to participate if they had OUD and had initiated treatment in the past month. Participants (n = 244) completed a semi-structured interview using the Addiction Severity Index-Lite.

RESULTS: At baseline, 37.70% of participants reported significant thoughts of suicide over their lifetime and 27.46% reported suicidal attempts over their lifetime. Logistic regression analyses were used to identify predictors …

Opioid Overdose: Rural Georgia Vs. Urban Georgia - Who's Winning The Battle?, Zizah-Wosseni Blair, Justice Dove, Didem Aydin, Stacie Fairley

Research Day

INTRODUCTION: The opioid crisis is a major public health issue affecting communities across the United States, including Georgia. The widespread misuse of prescription and illicit opioids has led to a significant increase in opioid-related overdoses and deaths. The impact on Georgia communities has been devastating, affecting individuals from all walks of life and causing significant harm to families and communities. The Georgia Department of Public Health reported that the number of drug overdose deaths in the state rose by 61.9% from 2019 to 2021. Rural and Urban communities in Georgia face unique challenges in addressing this epidemic. Rural communities often …

Outcomes From An Addiction Medicine Elective For 2nd Year Pcom Do Students, Rachel Caulkins, Anna Klunk, Christopher Suttera, Kayleigh Vanduzer, Frederick J. Goldstein

Research Day

Introduction: According to the 2020 National Survey on Drug Use and Health, 40.3 million people aged 12 or older had a past-year substance use disorder (SUD). However, the median number of hours of content discussing this clinical issue in medical schools is seven hours. At the PCOM Philadelphia campus, 50 Second Year students (allowable limit) participated in the first Addiction Medicine Elective course in Winter 2022. This was a 6-week long program with one 2-hour session at night (6–8 pm) per week. Classes consisted of sessions with physicians having experience with SUD patients, testimony from those with SUD, Narcan training, …

Is Acupuncture Effective In Reducing Opioid Cravings In Detoxifying Opioid Abusing Adults?, Sarah Kish

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is acupuncture effective in reducing opioid cravings in detoxifying opioid abusing adults?”

STUDY DESIGN: A review of three RCTs published in English, each of which was published in 2009, 2013 and 2014 respectively.

DATA SOURCES: Three randomized controlled trials (RCTs) published in peer-reviewed journals that evaluate the effectiveness of acupuncture to reduce opioid cravings found via PubMed and ScienceDirect.

OUTCOMES MEASURED: Opioid cravings via 100 millimeter analog scale score, the Maudsely craving score consisting of five-point Likert scales and withdraw symptoms as measured by a 4-point …

Is Acupuncture A Beneficial Therapy For The Treatment Of Alcohol Dependence?, Jamie E. Mcginn

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not acupuncture is a beneficial therapy for the treatment of alcohol dependence.

STUDY DESIGN: Review of three randomized controlled trails (RCTs) which were published in 2007, 2015, and 2016.

DATA SOURCES: All articles were presented in English and taken from peer reviewed journals found on PubMed.

OUTCOMES: The various symptoms of alcohol dependence; from withdrawal, cravings, and use were assessed through various methods. Alcohol withdrawal symptoms were assed using the alcohol-withdrawal syndrome scale, alcohol craving was assed using a Visual Analogue Scale, and alcohol use was measured …

Is Gabapentin Effective In Reducing Heavy Drinking And Alcohol Related Insomnia In Alcohol Dependent Patients?, Benjamin Michalsky

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is gabapentin effective in reducing heavy drinking and alcohol related insomnia in alcohol dependent patients?”

STUDY DESIGN: Review of three English language primary studies, one published in 2008 and two others in 2013.

DATA STUDIES: Three double blind, randomized controlled trials (RCTs) analyzing the effects of gabapentin therapy in attempting to reduce heavy drinking and alcohol related insomnia in alcohol dependent patients were found via PubMed and Cochrane databases.

OUTCOMES MEASURED: The reduction in alcohol consumption and improvement in alcohol related insomnia were measured through the …

Is Sublingual Buprenorphine Treatment Effective And Efficient When Compared To Traditional Neonatal Opium Solution (Morphine) In Treating Newborns With Neonatal Abstinence Syndrome?, Abigail G. Stefanides

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether sublingual buprenorphine treatment is effective and efficient when compared to traditional neonatal opium solution (morphine) in treating newborns with neonatal abstinence syndrome (NAS).

Study Design: Review of one randomized active-control clinical trial, one randomized doubleblind, double-dummy clinical trial, and one retrospective cohort analysis.

Data Sources: All articles were published in English between the years of 2011 and 2017. Articles were obtained from peer-reviewed journals and databases using PubMed and Embase.

Outcomes: Outcomes measured were length of stay using the neonates birth date and hospital discharge date as well …

Is Yoga Effective In Preventing Nicotine Cravings During Smoking Cessation In Adults?, George F. Donohue

PCOM Physician Assistant Studies Student Scholarship

No abstract

A Systematic Review On The Use Of Psychosocial Interventions In Conjunction With Medications For The Treatment Of Opioid Addiction, K Dugosh, A. Abraham, B. Seymour, K. Mcloyd, M. Chalk, David Festinger

PCOM Scholarly Papers

Opioid use and overdose rates have risen to epidemic levels in the United States during the past decade. Fortunately, there are effective medications (ie, methadone, buprenorphine, and oral and injectable naltrexone) available for the treatment of opioid addiction. Each of these medications is approved for use in conjunction with psychosocial treatment; however, there is a dearth of empirical research on the optimal psychosocial interventions to use with these medications. In this systematic review, we outline and discuss the findings of 3 prominent prior reviews and 27 recent publications of empirical studies on this topic. The most widely studied psychosocial interventions …

Tapestry Of Hope: Inspiration & Victory In The Face Of Adversity, Anna Bossert, Amy Surti

Bridging the Gaps Posters 2014

No abstract provided.

Substance Abuse Recovery: Mind, Body, And Soul, Chinwendu Opara, Aisha Uddin

Bridging the Gaps Posters 2014

No abstract provided.

Does The Use Of Varenicline For Smoking-Cessation Therapy Create Or Increase Depression In Patients Without Existing Depressive Illness?, Brett R. Brown

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of varenicline for smoking-cessation therapy creates or increases depression in patients without existing depressive illness.

STUDY DESIGN: Review of two randomized controlled trials published in 2011 and one observational cohort study published in 2009, all English language.
DATA SOURCES: Two randomized, double-blind, controlled clinical trials comparing varenicline to placebo in smoking cessation, and one observational cohort study comparing varenicline use within subjects. All articles were found using PubMed and EBSCO.

OUTCOMES MEASURED: Changes in depression was evaluated using the MontgomeryÅsberg Depression Rating Scale …

Does Nicotine Replacement Therapy Reduce The Withdrawal Symptom Of Craving, Or Urge To Smoke, In Dependent Adult Smokers During Smoking Cessation?, Theresa Dijoseph

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not nicotine replacement therapy reduces the withdrawal symptom of craving, or urge to smoke, in dependent adult smokers during smoking cessation.

STUDY DESIGN: Systematic review of three English language and peer-reviewed randomized-controlled trials published in 2009, 2010, and 2011.

DATA SOURCES: One single-blinded randomized-controlled crossover trial, one double-blinded, placebo controlled, randomized-controlled crossover trial, and one single-blinded, placebo controlled, randomized-controlled crossover trial

OUTCOMES MEASURED: Withdrawal symptoms of craving, irritability, difficulty concentrating, and restlessness were measured on a 100mm visual analog scale (VAS). Adverse effects (AEs) of mouth and …

Pharmacotherapy Safety And Efficacy In Adolescent Smoking Cessation, Jennifer Lincoln

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: To determine whether or not pharmacotherapy is a safe and effective treatment option for smoking cessation in adolescents