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Full-Text Articles in Medicine and Health Sciences
The More The Merrier: High-Throughput Single-Molecule Techniques, Flynn R. Hill, Enrico Monachino, Antoine M. Van Oijen
The More The Merrier: High-Throughput Single-Molecule Techniques, Flynn R. Hill, Enrico Monachino, Antoine M. Van Oijen
Faculty of Science, Medicine and Health - Papers: part A
The single-molecule approach seeks to understand molecular mechanisms by observing biomolecular processes at the level of individual molecules. These methods have led to a developing understanding that for many processes, a diversity of behaviours will be observed, representing a multitude of pathways. This realisation necessitates that an adequate number of observations are recorded to fully characterise this diversity. The requirement for large numbers of observations to adequately sample distributions, subpopulations, and rare events presents a significant challenge for single-molecule techniques, which by their nature do not typically provide very high throughput. This review will discuss many developing techniques which address …
Tunability Of The Co Adsorption Energy On A Ni/Cu Surface: Site Change And Coverage Effects, Erik Vesselli, Michele Rizzi, Sara Furlan, Xiangmei Duan, Enrico Monachino, Carlo Dri, Angelo Peronio, Cristina Africh, Paolo Lacovig, Alfonso Baldereschi, Giovanni Comelli, Maria Peressi
Tunability Of The Co Adsorption Energy On A Ni/Cu Surface: Site Change And Coverage Effects, Erik Vesselli, Michele Rizzi, Sara Furlan, Xiangmei Duan, Enrico Monachino, Carlo Dri, Angelo Peronio, Cristina Africh, Paolo Lacovig, Alfonso Baldereschi, Giovanni Comelli, Maria Peressi
Faculty of Science, Medicine and Health - Papers: part A
The adsorption energy of carbon monoxide on Ni ad-islands and ultra-thin films grown on the Cu(110) surface can be finely tuned via a complex interplay among diffusion, site change mechanisms, and coverage effects. The observed features of CO desorption can be explained in terms of migration of CO molecules from Cu to Ni islands, competition between bridge and on-top adsorption sites, and repulsive lateral adsorbate-adsorbate interactions. While the CO adsorption energy on clean Cu(110) is of the order of 0.5 eV, Ni-alloying allows for its controlled, continuous tunability in the 0.98-1.15 eV range with Ni coverage. Since CO is a …
Radical Generation From The Gas-Phase Activation Of Ionized Lipid Ozonides, Shane R. Ellis, Huong T. Pham, Marc In Het Panhuis, Adam J. Trevitt, Todd W. Mitchell, Stephen J. Blanksby
Radical Generation From The Gas-Phase Activation Of Ionized Lipid Ozonides, Shane R. Ellis, Huong T. Pham, Marc In Het Panhuis, Adam J. Trevitt, Todd W. Mitchell, Stephen J. Blanksby
Faculty of Science, Medicine and Health - Papers: part A
Reaction products from the ozonolysis of unsaturated lipids at gas¿liquid interfaces have the potential to significantly influence the chemical and physical properties of organic aerosols in the atmosphere. In this study, the gas-phase dissociation behavior of lipid secondary ozonides is investigated using ion-trap mass spectrometry. Secondary ozonides were formed by reaction between a thin film of unsaturated lipids (fatty acid methyl esters or phospholipids) with ozone before being transferred to the gas phase as [M + Na]+ ions by electrospray ionization. Activation of the ionized ozonides was performed by either energetic collisions with helium buffer-gas or laser photolysis, with …
Calcium Carbonate Production And Contribution To Coastal Sediments, Colin D. Woodroffe, John W. Farrell, Frank R. Hall, Peter T. Harris
Calcium Carbonate Production And Contribution To Coastal Sediments, Colin D. Woodroffe, John W. Farrell, Frank R. Hall, Peter T. Harris
Faculty of Science, Medicine and Health - Papers: part A
Biological production of calcium carbonate in the oceans is an important process. Although carbonate is produced in the open ocean (pelagic, see Chapter 5), this chapter concentrates on production in coastal waters (neritic) because this contributes sediment to the coast through skeletal breakdown producing sand and gravel deposits on beaches, across continental shelves, and within reefs. Marine organisms with hard body parts precipitate calcium carbonate as the minerals calcite or aragonite. Corals, molluscs, foraminifera, bryozoans, red algae (for example the algal rims that characterize reef crests on Indo-Pacific reefs) are particularly productive, as well as some species of green algae …
An Incised Shell Object From Baradostian (Early Upper Palaeolithic) Layers In Shanidar Cave, Iraqi Kurdistan, Chris Hunt, Evan Hill, Tim Reynolds, Dlshad Abdulmutalb, Lucy Farr, Ross Lane, Katherine A. Szabo, Graeme Barker
An Incised Shell Object From Baradostian (Early Upper Palaeolithic) Layers In Shanidar Cave, Iraqi Kurdistan, Chris Hunt, Evan Hill, Tim Reynolds, Dlshad Abdulmutalb, Lucy Farr, Ross Lane, Katherine A. Szabo, Graeme Barker
Faculty of Science, Medicine and Health - Papers: part A
Shanidar Cave contains one of the most important Palaeolithic archaeological sequences in West Asia. During renewed excavations of Baradostian (Upper Palaeolithic) layers in the cave, an incised land-snail shell fragment was recovered. A natural cause seems unlikely and it does not appear likely to reflect palaeoeconomic functions. It is suggested tentatively that this may have been made during manufacture of a composite artefact designed for visual display. Although Upper Palaeolithic ornaments are often reported, composite ornaments of this period are rather unusual.