Medicine and Health Sciences Commons^™

Survival Disparities Between Border And Non-Border Counties In Colorectal Cancer Patients Using The Tcr, Michael Machiorlatti, Michael Brian Lapelusa

Research Colloquium

Along the US Texas Mexico border constant migration, developing medical infrastructure and income disparity leads to poorer access to healthcare and poorer health outcomes. Given 32 of the 254 counties in TX are on the border with roughly 9.8% of the Texas residing in these counties (2.8 million people), this represents a significant population susceptible to adverse health outcomes. We investigate comparisons between border and non-border counties as well as how sociodemographic and diagnostic criterion influence survival of colorectal cancer. Data was obtained from the Texas Department of State Health Service’s TCR. Patients were 18 or older and excluded for …

Variation In Functional Pelvic Tilt In Patients Undergoing Total Hip Arthroplasty With Acetabular Dysplasia, Myung-Jin Cha, Joel Wells, Yin Xi, Avneesh Chhabra

Research Colloquium

Purpose: It is important to clarify the link between acetabular dysplasia and pelvic tilt to optimize surgical planning and postoperative outcomes. We sought to investigate functional pelvic tilt in patients undergoing total hip arthroplasty with acetabular dysplasia.

Materials & Methods: From 2014 to 2020, pre-operative AP Pelvis X-rays, CT scans, and other patient-specific data such as pelvic tilt, lumbar lordotic angle, etc were collected as part of surgical planning for total hip arthroplasty. From this database, we investigated 678 female patients under the age of 50 that had undergone preoperative standing AP pelvis X-rays. Analysis was performed by investigating how …

Phylogenomics Reveals The History Of Host Use In Mosquitoes, John Soghigian, Charles Sither, Silvia Andrade Justi, Gen Morinaga, Brian K. Cassel, Christopher J. Vitek, Todd Livdahl, Siyang Xia, Andrea Gloria-Soria, Jeffrey R. Powell

School of Integrative Biological and Chemical Sciences Faculty Publications and Presentations

Mosquitoes have profoundly affected human history and continue to threaten human health through the transmission of a diverse array of pathogens. The phylogeny of mosquitoes has remained poorly characterized due to difficulty in taxonomic sampling and limited availability of genomic data beyond the most important vector species. Here, we used phylogenomic analysis of 709 single copy ortholog groups from 256 mosquito species to produce a strongly supported phylogeny that resolves the position of the major disease vector species and the major mosquito lineages. Our analyses support an origin of mosquitoes in the early Triassic (217 MYA [highest posterior density region: …

Improving Health Literacy Among Transgender/ Gender Non-Conforming People Using Social Media, Isha Mittal, Michelle Cordoba Kissee

Research Colloquium

Background: Health literacy has been elicited as a barrier to healthcare amongst LGBT individuals. Social media has become a popular force in transmitting health information, but often time lacks evidence-based information.

Aims/purpose: The TikTok channel GenderDefenders was created to address the lack of reliable evidence-based information for transgender and gender-non conforming (TGNC) individuals.

Methods: Data was collected from current TikTok videos that were tagged with TGNC terminology to identify gaps in knowledge and commonly asked questions. Themes were selected and educational video recordings were created using WPATH and UCSF guidelines for transgender healthcare. Some topics included what …

Addressing Cervical Cancer Disparities In Texas: Expansion Of A Community-Based Prevention Initiative For Medically Underserved Populations, Samantha H. Batman, Melissa L. Varon, Maria Daheri, Tony Ogburn, Saul D. Rivas, Laura Guerra, Paul Toscano, Monica Gasca, Lori Campos, Savanah Foster

School of Medicine Publications and Presentations

Although cervical cancer is preventable, significant disparities exist in access to screening and prevention services. In medically underserved areas (MUAs) of Texas, these rates are 55% higher compared to the remainder of the US. In 2019, we expanded a multicomponent, comprehensive program to improve cervical cancer prevention in partnership with 13 clinics and mobile vans in MUAs of Texas. Our multicomponent intervention program consists of community education and patient navigation coupled with a training/mentoring program for local medical providers to perform diagnostic procedures and treatment for patients with abnormal screening results. Hands-on training courses to learn these skills are coupled …

Quality Improvement Project To Increase Hepatitis C Virus Screening For Ambulatory Gme Internal Medicine Clinic Patients, Nghia Nguyen, Karrar Al Gburi, Arturo Suplee, Jarrad Mcadams, Serag Fares, Carol Soler, Ans Albustamy, Jorge Alejandro Bernal, Sumandeep Brar, J. Paredes

Research Symposium

Background: In 2020, CDC established new guideline expanding Hepatitis C virus (HCV) screening to all adults aged 18 to 79 years. Our QI project objective is to enhance HCV screening amongst the UTRGV-DHR IM department by establishing suitable reminders and educational sessions.

Methods: We reviewed HCV screening status of all adult patients 18 to 79 years old from June 1^st 2020 to December 1^st 2020. We then provided one lecture on the new screening recommendation from CDC 2020 guideline. We also encouraged residents to educate patients on the importance of HCV screening, and to identify and overcome barriers …

Project: Center For Diabetes And Metabolism [Centro De Diabetes Y Metabolismo: Cedimet], A Collaborative Dream Comes True, Claudia Munguia-Cisneros, Edith Cantu, Carlos Ramirez-Pfeiffer, Adriana L. Perales-Torres, Esperanza M. Garcia-Oropeza, Estrella Y. Martinez-Lopez, Alvaro Diaz-Badillo, Joselin Hernandez-Ruiz, Alberto O. Chavez-Velazquez, Lucia M. Perez-Navarro, Beatriz Tapia, Juan C. Lopez-Alvarenga

Research Symposium

Reynosa urban area has 690,000 inhabitants (384,000 adults >20 years old), 35% moved from other states. The use of cell phones is in 81%, personal computer or laptop with 29%. The prevalence of overweight is 39%, obesity 36%, and T2D 13%. The expected adult population with T2D is 49,900 individuals. The are 5 clinics prepared to attend T2D, and few with specialized personnel.

The CeDiMet is a collaborative clinic involving health personnel and researchers from the Universidad Mexico Americana del Norte, Universidad Autonoma de Tamaulipas, Hospital General de Mexico “Dr. Eduardo Liceaga”, University of Texas Rio Grande Valley, and the …

Proactively Preventing Medical Errors: A Student-Led Approach To Patient Safety In Pre-Clinical Curriculum, Sahar Panjwani, Daniel Nwosuocha, Nelson D. Gonzalez, Ayleen Godreau

Research Symposium

Introduction: Preventable medical errors are currently the third leading cause of death in the United States following heart disease and cancer (1). This study was designed to assess the change in knowledge from earlier education of medical students during pre-clinical years.

Methods: Patient safety trainings have been conducted for two years for interested first and second-year medical students and responses are assessed through a pre-test, immediate post-test, 3-month post-test, and 6-month post-test. The survey assesses student knowledge on aspects of patient safety and has Likert scale questions assessing if the training influenced students’ desire to learn about patient safety. …

Pharmacoeconomics Of Metastatic Colorectal Cancer Treatment With Targeted Therapies Guided By Companion Molecular Diagnostics, Luis E. Fernández-Garza, Hector Sánchez-Ibarra, Daniela Treviño-Sáenz, Hugo A. Barrera-Saldaña

Research Symposium

Background: To guide the treatment with monoclonal antibodies (MAbs) against the epidermal growth factor receptor (EGFR) of metastatic colorectal cancer (mCRC), the FDA recommends prior companion molecular diagnosis (CMDx). It initially recommended screening for mutations in exon 2 of the KRAS gene, and most recently to extend to screening to exons 2, 3, and 4 of KRAS and 2, 3, and 4 of NRAS genes; furthermore, to evaluate the BRAF exon 15 mutation status (including V600E). To date, no studies have been done to compare the cost-benefit of these different CMDXs.

Methods: We have compared the cost of treatment without …

Malignant Colorectal Cancer In The Rio Grande Valley: A Demographical Study, Kevin M. Camstra, Vijian Dhevan

Research Symposium

Background: There is abundant demographical data available that provides an excellent general statistical overview of colorectal cancer (CRC) within the Hispanic population in South Texas. Much is known about the overarching trends regarding incidence, prevalence, mortality and screening rates among this specific population as compared to other racial and ethnic groups at the state and national levels. Despite our understanding of these broad trends, few studies have taken a step inward to provide a closer demographical analysis of a CRC population here in the Rio Grande Valley. In this study, we narrow the scope and take a closer look …

Learners Engaging With Hispanic Communities To Address Covid19 Inequities By Developing A Cultural Competence Guide For Public Health Messaging, Madeline Elaine Huff, Molly Chapman, Chasity Collier, Giuiseppe Fonseca Badillo, Shuchita Jhaveri, Ayesha Khan, Sabrina R. Orta, Zuni Ortega, Lina Pedraza Sanchez, Maria Pesantez Borja, Rosalind Reyes, Daniela Santos Cantu, Chelsea H. Chang

Research Symposium

Introduction: The Rio Grande Valley (RGV) has the highest rates of obesity and diabetes nationwide which have compounded the impact of COVID-19. We propose addressing underlying mistrust and systemic racism through a resident-and-student-learner-led, community-engaged, educational public health campaign targeting the Hispanic community in the RGV.

Methods: Twelve students were provided interdisciplinary leadership skills in a community-engaged public messaging campaign covering issues of COVID-19 inequities. Learners used these skills to engage with clinic community partners in qualitative interviews regarding the patient population to guide the creation of a culturally competent public health messaging rubric for the Hispanic community.

Results: Pre-intervention survey …

Expanding Health Professional Education In The Rio Grande Valley During The Covid-19 Pandemic, Sabrina R. Orta, Samantha G. Alvarado, Shuchita Jhaveri

Research Symposium

Purpose: The COVID-19 Pandemic has prompted innovation in health professional education, such that learners are able to recognize and mitigate healthcare disparities in the outcomes of vulnerable populations. The objective of our project was to increase education on preventing, preparing for, and responding to COVID-19 and other locally prevalent infectious diseases that disproportionately affect RGV communities.

Description: This project had 3 goals: (1) provide learners with virtual patient-interaction simulations (2) provide interactive training modules on the identification, prevention, and treatment of infectious diseases affecting South TX and strategies to increase child vaccinations, and (3) provide learners an opportunity to coordinate …

Epidemiological Algorithm And Early Molecular Testing To Prevent Covid-19 Outbreaks In A Mexican Oncologic Center, Moises González-Escamilla, Diana C. Peréz-Ibave, Carlos H. Burciaga-Flores, Vanessa N. Ortiz-Murillo, Genaro A. Ramírez-Correa, Patricia Rodríguez-Niño, Rafael Piñeiro-Retif, Hazyadee F. Rodríguez-Gutiérrez, Orlando D. Solis-Coronado, Juan F. González-Guerrero, Oscar Vidal-Gutiérrez, María Lourdes Garza-Rodríguez

Research Symposium

Introduction: Prevention strategies and detection of latent COVID-19 infections in oncology staff and oncologic patients are essential to prevent outbreaks in a cancer center. In this study, we used two statistical predictive models in oncology staff and patients from the radiotherapy area to prevent outbreaks and detect COVID-19 cases.

Methods: Staff and patients answered a questionnaire (electronic and paper surveys, respectively) with clinical and epidemiological information. The data was collected through two online survey tools: Real-Time Tracking (R-Track) and Summary of Factors (S-Facts). According to the algorithm's models, cut-off values were established. SARS-CoV-2 qRT-PCR tests confirmed the algorithm's positive individuals. …

Childhood Cancer Survival In The Highly Vulnerable Population Of South Texas: Persistent Challenges For Adolescents And Hispanic Ethnicity, Shenghui Wu, Y. N. Liu, M. Williams, C. Aguilar, A. G. Ramirez, R. Mesa, G. E. Tomlinson

Research Symposium

Background: This study examines childhood cancer survival rates and prognostic factors related to survival in the majority Hispanic population of South Texas (STX), whereas most other population studies in childhood cancer survival focus on populations with relatively few Hispanics.

Methods: The population-based cohort study used Texas Cancer Registry data (1995-2017) to examine survival and prognostic factors.

Results: The 5-year relative survival rate for STX cancer patients diagnosed at 0–19 years was 80.3% for all races/ethnicity. Hispanics had statistically significant lower 5-year relative survival rates than non-Hispanic Whites (NHW) for male and female together diagnosed at age ≥ 5 years. When …

Characterization Of Oral Cavity And Oropharyngeal Cancer In The Texas Rio Grande Valley, Jared A. Sperling, Rachel Giese

Research Symposium

Background: Cancers of the oral cavity (OC) and oropharynx (OP) account for 3% of cancers diagnosed in the United States each year. A primary cause of death among the Hispanic population in the United States is cancer, accounting for 20% of annual mortality. The Rio Grande Valley (RGV) is a medically-underserved area of South Texas with a large Hispanic population facing health disparities. In this study, we examine the incidence and mortality of OC and OP cancer in the RGV.

Methods: CDC population-level incidence and mortality rate per 100,000 of OC/OP cancer among patients in the RGV counties of Hidalgo …

Awareness Of Genetic Testing For High-Risk Cancer Among Different Racial Groups In The United States, Okechukwu C. Erinne, Modupe O. Onigbogi

Research Symposium

Background: Genetic testing for high-risk cancer can provide information on personal risk of developing cancer, as well as diagnosis, prognosis and treatment once cancer has been detected.

Methods: Data for this study were obtained from the Health Information National Trends (HINTS 5, Cycle 4), conducted among U.S. adults (age ≥ 18 years) from February 24 to June 20, 2020. An equal probability sample of addresses were stratified, and an adult was selected from each household. Data analysis was conducted 3,865 respondents who completed the survey. The primary outcome was awareness of genetic testing for high-risk cancer (GTHC). We …

The Impact Of Virtual Learning On Health Literacy: Lessons From A Virtual Townhall Held By The Lamar University Recovery And Resilience Academy, Margot Gage Witvliet, Chiung-Fang Chang

Research Symposium

Background: The COVID-19 pandemic shut down the entire world. This caused universities and addiction recovery programs to get creative on how to reach community needs. Many professors found themselves teaching online for the first time. Apps for mental health and addiction recovery programs grew exponentially. Information on how adequate virtual programs perform are mixed. We investigate the extent to which a virtual program can increase health literacy. To accomplish this, the professors of the sociology program launched the Recovery and Resilience Academy (RnR Academy). The aim of RnR Academy is to serve as an outreach and educational center for the …

The Eyes Beyond The Screen: Digital Media Policy And Child Health, Yahia Al-Qudah

Research Symposium

Background: Modern communication technology and digital media have provided society with a foundation for instant messaging. Pictures, videos, and texts connect individuals with families, friends, and the world. Consequently, digital media has accelerated exposure to risk in which children and adolescents are most vulnerable. This project’s objective is to 1) congregate and highlight current knowledge about the impact of digital media on child health, and 2) underline deficiencies in related laws and regulations as well as offer solutions in digital media policy.

Methods: A systematic literature review was conducted through the JAMA Pediatrics database with keywords such as “digital media,” …

The Role Of Community Pharmacists In The Provision Of Medication For Opioid Use Disorder Treatment In Rio Grande Valley, Tamara Al Rawwad, Ammar Kawaleet, Lydia Aguilera, Adrian Sandoval

Research Symposium

Background: The misuse of opioids, including prescription opioids, heroin, and fentanyl, has reached epidemic proportions in the US, resulting in more than 68,000 overdose deaths in 2020, and a total of $78.5 billion a year of economic burden. In response to this crisis, the US Department of Health and Human Services (DHHS) released a strategic plan to combat opioid abuse and misuse, recommending a multidisciplinary approach, including the inclusion of pharmacists in the efforts. The aim of this study is to examine pharmacists’ perception of their role in the provision of medication for opioid use disorders (MOUD) in addition to …

Characterization Of Prostate Cancer In Transgender Women, Simita Gaglani, Rajveer Purohit, Ashutosh Tewari, Dara Lundon, Natasha Kyprianou

Research Symposium

Background: The risk of developing prostate cancer (PC) in transgender women is unknown. Many patients are unaware that the prostate is not removed during male-to-female surgical transition. It is unclear what the exposure of estrogens and androgen blockers in these transgender patients has on the prostate. Our aim was to examine and characterize the different presentations of PC in published cases and augment this with an additional case series from one institute.

Methods: A retrospective review of prospectively maintained medical records was performed identifying features of PC diagnoses in transgender women. These included age, duration of feminizing hormone therapy, PSA …

The Fortify Resilience Initiative, Nausheen Jamal, Deepu George, Maria Hernandez, Evan Garcia, Myrna Ruiz, Salvador Arellano Iii

Research Symposium

Purpose: The Fortify Resilience Initiative focuses on building and sustaining a culture of wellbeing for Residents and Fellows (R/Fs) at The University of Texas Rio Grande Valley (UTRGV) School of Medicine’s (SOM) Graduate Medical Education (GME) residency and fellowship programs. In order to address the multitude of threats to physician wellness and to mitigate the silent, but pernicious effects of burnout on these physician learners serving in the RGV, this Initiative from the Office of GME will strengthen existing wellbeing pathways while expanding additional solutions that will work to sustain wellbeing. Utilizing a combination of prevention, promotion, and intervention strategies …

Implementation Of A Training Module On Alcohol Prevention For Promotoras On A Border Community In The Rio Grande Valley., Noe Garza, J Escareno, Alvaro Diaz-Badillo, Ihsan Salloum

Research Symposium

Background: Complications due to unhealthy alcohol use are widely spread, and there is a significant unmet need for prevention and treatment in the community. The South Texas-Mexico border region consists of over ninety percent of Hispanics and suffers from a significant shortage of physicians. Alcohol-related problems are highly unrecognized and untreated in this large Hispanic population due to the shortage of healthcare providers, low education levels, and limited trust in the health care system. Prevention efforts should be designed to prevent or reduce the risk of developing alcohol addiction.

Methods: The proposed module focuses on enhancing the Promotoras or Community …

Critical Reflection In Practice: Generating Knowledge From The Interactions With Promotores For Engagement In Neurocognitive Disorders, Noe Garza, Ney Alliey-Rodriguez, Rosa V. Pirela, Gladys E. Maestre

Research Symposium

Background: Colonias are underserved areas along the Texas-Mexico border, with high incidences of neurocognitive disorders, dementia, and Alzheimer's disease (AD). Our goal is to build capacity to reduce risk, facilitate treatment for affected individuals, and provide caregiver support. Our aim was to construct an approach that was reflective and would reveal the rich and diverse ways in which people make meaning of their experiences and interactions with scientists, faculty, staff and students.

Methods: We examined our work with local community health workers. (CHWs), promotores in Spanish, to establish contact with, engage, mobilize, and educate the Hispanic communities of the Lower …

Trusted Sources Of Health Information During The Covid-19 Pandemic, Michael Machiorlatti, Candace Robledo, Cliff Clark

Research Symposium

Background: As the role of media has evolved with display and consumption of health information, the need to decipher the quality of the information has become exceedingly important. This became more important during the covid-19 pandemic, when information was being formulated and released nearly real-time. Prior to the pandemic, government agencies, health professionals and authorities were generally trusted sources of information. Additionally, information passed more casually through family and acquaintances was also something people tended to rely upon. This paper explores the self-reported trustworthiness of different health information sources during the pandemic and also seeks to rank the importance from …

Interdisciplinary Integrated Primary And Behavioral Healthcare (I2pbh) Initiative, John Ronnau, Deepu George, Maria Hernandez, Evan Garcia, Myrna Ruiz

Research Symposium

Purpose: The Interdisciplinary Integrated Primary and Behavioral Healthcare (I²PBH) initiative will train University of Texas Rio Grande Valley (UTRGV) mental health graduates to deliver high quality, evidence-based Integrated Behavioral Health (IBH) services in the Rio Grande Valley (RGV) – a high-need, high-demand, medically underserved Hispanic region along the US-Mexico border. Specifically, the I²PBH initiative will train 24 UTRGV mental health graduates annually to deliver high-quality Integrated Behavioral Health (IBH) clinical services through the evidence based Primary Care Behavioral Health (PCBH) model. With a training emphasis on basic/advanced theory and clinical skills in the PCBH model, students …

Clinical Characteristics And Risk Factors For Mortality During The 'First Wave' Of Covid-19 In Reynosa, Tamaulipas, Luis G. Vargas Garcia, Francisco E. Díaz Cisneros, Antonio Gutiérrez Sierra, Juan Rosales Martínez, Manlio F. Lara Duck, Netzahualcoyotl Mayek Pérez

Research Symposium

Background: The COVID-19 pandemic has impacted public health in Mexico. As of February 2020, there have been at least four "waves" of contagion that resulted in 5.82 million positive cases and more than 325 thousand deaths. At the beginning of the COVID-19 pandemic, hospital and population-based information was available, frequently with non-specific symptoms. Little was known about the risk factors for mortality in specific conditions. We described the clinical characteristics of patients with COVID-19 in Reynosa, Tamaulipas during 2020 and identified the risk factors for mortality.

Methods: The COVID-19 cases registered from March to November 2020 in Reynosa were divided …

Complex Gynecology Clinic, Saul D. Rivas, Elissa Serapio, Tony Ogburn, John Ronnau, Alejandra Vega, Angela Tanguma, Andrea K. Contreras

Research Symposium

Purpose: The Area Health Education Center (AHEC) Complex Gynecology Clinic aims to reduce the shortage of women’s primary care providers in rural and medically underserved communities. The Complex Gynecologic clinic provides high quality- evidence based care to women at low or no cost regardless of immigration status, socioeconomic status, educational attainment, and age who might otherwise be unable to receive much needed care in other sites in the RGV.

Description: Some of the services offered, via grant funding, include preventive services such as well women exams, cervical cancer screening, and family planning. As well as work up and treatment for …

Comparing Stroke Symptom Recognition And Intervention Times In The Rio Grande Valley, Joshua M. Ninan, Kelsey Baker

Research Symposium

This is a retrospective study that aims to evaluate the duration from onset of stroke-like symptoms to presentation to medical facilities for aid in the Rio Grande Valley. The main goal of the study is to understand the extent of pre-hospital delays with regards to the treatment of stroke in the RGV.

Utrgv Student Run Clinic: The Past, The Present, And The Future, Jessica Flores, Elizabeth Althaus, Uchechi Ehiemua, Elio Garcia Sosa, Lucinda Hinojosa, Andrew Kolodziej, Dikachi Osaji, Asma Syed, Chelsea Chang

Research Symposium

Purpose: The UTRGV SOM Student Run Clinic (SRC) is a student- led organization that provides free primary care and promotes health equity in the Rio Grande Valley. Through the SRC, barriers of access to healthcare and health promotion are targeted, especially by emphasizing health literacy and patient advocacy. The SRC benefits not only our patients but medical students who work in the clinic, learning about the unique needs and culture of the underserved community while gaining clinical experience.

Description: The SRC brings teams of volunteer medical students and physicians to Peñitas, TX to provide free primary healthcare to vulnerable populations, …

Quality Of Nutritional Care During Pregnancy: Folic Acid And Vitamin D Supplementation, Isabel Omaña-Guzmán, Monica Ancira-Moreno, Cecilia Pérez-Navarro, Sonia Hernández-Cordero, Soraya Burrola Méndez, Eric Monterrubio-Flores, Arturo Bautista Morales, Omar Acosta Ruiz, Constanza Bernat, Belén Sánchez,, Ariana Cajero

Research Symposium

Backgrounds: Folic acid (FA) and vitamin D supplementation is recommended during pregnancy. Quality nutritional care during pregnancy should include the supplementation of these vitamins. Therefore, the aim of this study was to assess the quality of nutritional care regarding supplementation during pregnancy in primary health care units in six states of Mexico (Estado de México, Oaxaca, Yucatán, Chihuahua, Veracruz and Chiapas).

Methods: A mixed study was conducted. An indicator (formed by two sub-indicators) to assess the quality of nutritional care focused on FA and vitamin D supplementation in pregnancy was developed and validated. To assess the quality of care, a …