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Many Hands Make Light Work: Crowdsourced Ratings Of Medical Student Osce Performance, Mark Grichanik Apr 2017

Many Hands Make Light Work: Crowdsourced Ratings Of Medical Student Osce Performance, Mark Grichanik

USF Tampa Graduate Theses and Dissertations

Clinical skills are often measured using objective structured clinical examinations (OSCEs) in healthcare professions education programs. As with assessment centers, it is challenging to provide learners with effective feedback due to burdensome human capital demands. The aim of this dissertation was to evaluate the viability of using a crowdsourced system to gather OSCE ratings and feedback. Aggregating evaluations of student performance from a crowd of patient proxies has the potential to mitigate biases associated with single-rater evaluations, allow the patient a voice as the consumer of physician behavior, improve reliability, reduce costs, improve feedback latency, and help learners develop a …


Adaptive Styles And Coping Strategies Of Youth Diagnosed With Cancer: Relationship To Well-Being, Psychosocial And Educational Adjustment, And Parents’ Adaptive Styles, Renee Corbett Oct 2016

Adaptive Styles And Coping Strategies Of Youth Diagnosed With Cancer: Relationship To Well-Being, Psychosocial And Educational Adjustment, And Parents’ Adaptive Styles, Renee Corbett

USF Tampa Graduate Theses and Dissertations

Although almost 16,000 children and adolescents are diagnosed with cancer each year, the incident rates have remained stable over recent years, and mortality has decreased consistently since 1975 (American Cancer Society, 2016). With increased survivorship, research and practice in pediatric oncology has focused more on the psychosocial well-being of patients during and after treatment. With research repeatedly indicating that patients and families appear to exhibit great resilience and adjustment, and low incidences of psychosocial difficulties (e.g., Kazak, 1994, Eiser et al. 2000), some researchers have examined adaptive style as a possible construct that may help explain the predominantly positive outcomes …


Moderation Analysis Of Bowel Function Among Nutrients And Physical Function Or Depression, As Well As Whether Bowel Function Is Related To Cognition In Older Adults, Jessie Alwerdt Jul 2016

Moderation Analysis Of Bowel Function Among Nutrients And Physical Function Or Depression, As Well As Whether Bowel Function Is Related To Cognition In Older Adults, Jessie Alwerdt

USF Tampa Graduate Theses and Dissertations

As we age, the risk for gut issues, such as smooth muscle tone, may be an underlying indirect or direct cause or risk factor for many age-related issues, such as frailty. Consequences of decreased motility and depleted epithelial barrier may result in nutrient deficiencies that may increase the risk for malnutrition (Brownie, 2006). Further, there is increasing evidence that there is a gut-brain-axis relationship that may influence cognition and mental health issues, such as depression and anxiety. While there are relationships established, the interconnections of these factors have yet to be fully understood.

This dissertation examined several relationships specific to …


Teacher Child Interaction Therapy: An Ecological Approach To Intervening With Young Children Who Display Disruptive Behaviors, Sara Marie Hinojosa Jul 2016

Teacher Child Interaction Therapy: An Ecological Approach To Intervening With Young Children Who Display Disruptive Behaviors, Sara Marie Hinojosa

USF Tampa Graduate Theses and Dissertations

A model of Teacher Child Interaction Therapy (TCIT) was implemented in two kindergarten classrooms of students (n = 2) who successfully completed Parent Child Interaction Therapy, but continued to demonstrate disruptive behaviors in the classroom. The current study first indicated that TCIT was implemented with integrity by both the therapists and teacher participants. Next, the effects of this intervention on the teacher’s skills, students’ disruptive behaviors, teacher’s stress, and teacher-child relationships were investigated. The treatment acceptability was also examined. Both visual and statistical analyses found a treatment effect in both cases was seen for both teachers’ increased use of positive …


The Relationship Of Attributions And Parental Characteristics With Parental Problem Recognition, Lindsey Heath Steding Jul 2016

The Relationship Of Attributions And Parental Characteristics With Parental Problem Recognition, Lindsey Heath Steding

USF Tampa Graduate Theses and Dissertations

A significant number of youth experience mental health disorders for which they suffer negative consequences. Although there are evidence-based therapies available to help children and their families, most youth do not receive treatment. Parental problem recognition is likely a primary barrier in this process. This study begins to address why parents may have difficulty recognizing mental health problems by extending existing models and integrating evidence about parental perceptions. Specifically, the study aimed to investigate the relationship between parental attributions and parents’ problem determination, and to examine the influence that parental characteristics have on this judgment process. Participants included 164 parents …


The Influence Of Motivational Salience On Attention Selection: An Erp Investigation, Constanza De Dios Jun 2016

The Influence Of Motivational Salience On Attention Selection: An Erp Investigation, Constanza De Dios

USF Tampa Graduate Theses and Dissertations

The current study used event-related potentials (ERPs) to investigate how motivational salience in the form of expectation violation influences spatial attention. The medial frontal negativity (MFN) ERP indexes expected value, being negative to unexpected punishments and positive to unexpected rewards. The P1 and N1 ERPs index spatial attention, being larger to stimuli in attended locations. This design attached motivational value to locations by making one visual hemifield economically rewarding (greater probability of a rewarding outcome) and the other punishing (greater probability of a punishing outcome). Keypresses to a dot probe following a reward-signifying stimulus were awarded money if correct, and …


The Effects Of Cognitive Training Among Individuals With Neurodegenerative Diseases, Elise Gabriela Valdes Jun 2016

The Effects Of Cognitive Training Among Individuals With Neurodegenerative Diseases, Elise Gabriela Valdes

USF Tampa Graduate Theses and Dissertations

With the growing older adult population, neurodegenerative diseases common in old age such as mild cognitive impairment (MCI) or Parkinson’s disease (PD) are becoming increasingly germane areas of research. Pharmacological treatments have thus far been unsuccessful in treating cognitive decline associated with these neurodegenerative disorders. Alternative interventions, such as cognitive training programs, have shown promise. The current dissertation contains three papers examining cognitive interventions in neurodegenerative diseases. The first paper examined the longitudinal effects of cognitive speed of processing training (SPT) among those with PD. Results showed that training gains seen at initial post-test were maintained three months later. The …


Genetic Moderators Of Cognitive Decline In The Health And Retirement Study, Shannon K. Runge Apr 2016

Genetic Moderators Of Cognitive Decline In The Health And Retirement Study, Shannon K. Runge

USF Tampa Graduate Theses and Dissertations

The current dissertation used a gene x environment (G x E) approach to examine the independent and interactive effects of specific genetic variants and participation in physical and cognitive/social activities (PA and CSA) on cognitive performance in 4,764 participants of the Health and Retirement Study. Using three-wave data, three sets of multi-level growth models were conducted to examine baseline, longitudinal, and interactive effects of genotype (i.e., ApoE, COMT, and BDNF) and CSA/PA on performance across five cognitive measures: immediate, delayed and total word recall, and serial 7s and backwards counting.

At baseline, the ApoE ε4 allele predicted …


Anti-Fat Attitudes And Weight Bias Internalization: An Investigation Of How Bmi Impacts Perceptions, Opinions And Attitudes, Laurie Schrider Mar 2016

Anti-Fat Attitudes And Weight Bias Internalization: An Investigation Of How Bmi Impacts Perceptions, Opinions And Attitudes, Laurie Schrider

USF Tampa Graduate Theses and Dissertations

Americans hold negative and judgmental attitudes towards obese and overweight individuals and these anti-fat attitudes and weight stigma have become a damaging form of discrimination. The internalization of weight bias and anti-fat attitudes contributes to negative health outcomes including: feelings of devalue, self-hate, anxiety, depression, body dissatisfaction and eating disturbances. The purpose of this study was to investigate weight bias internalization in individuals who perceive themselves as overweight as well as to examine differences in anti-fat attitudes among normal and overweight individuals. A sample of 202 male and females completed an online survey that assessed anti-fat attitudes via the Anti-Fat …


Neurophysiological Activity Related To Speech Production: An Erp Investigation, Adithya Chandregowda Nov 2015

Neurophysiological Activity Related To Speech Production: An Erp Investigation, Adithya Chandregowda

USF Tampa Graduate Theses and Dissertations

The event related potential (ERP) technique is enjoying widespread application in neurophysiological research due to its fine temporal resolution. Of relevance to this study are ERPs related to voluntary movements. The precision with which movement related processes could be recorded using the ERP technique was demonstrated by Gilden, Vaughan and Costa (1966) and Kutas and Donchin (1974, 1977, and 1980) who found that the readiness potential (RP) immediately preceding hand movement was larger over the hemisphere contralateral to the responding hand. Given that left hemisphere controls right hand movements and vice versa, their findings confirmed that the lateralized readiness potential …


An Animal Model Of Flashbulb Memory: Insights Into The Time-Dependent Mechanisms Of Memory Enhancement, Laura Ashley Bullard Nov 2015

An Animal Model Of Flashbulb Memory: Insights Into The Time-Dependent Mechanisms Of Memory Enhancement, Laura Ashley Bullard

USF Tampa Graduate Theses and Dissertations

The vivid memory of an emotional event, as well as memory for incidental details associated with the arousing event, has been referred to collectively as a “flashbulb memory”. An important aspect of flashbulb memory in people is that an emotional event enhances memory of contextual details, such as the weather, or clothes one was wearing at the time of the event. Therefore, an emotional event not only produces a detailed memory of the event, itself, but also enhances memory for contextual details that would otherwise not be remembered. The first goal of this work is to describe the development of …


The Effects Of Parent-Adolescent Communication And Parenting Style On The Physical Activity And Dietary Behaviors Of Latino Adolescents, Dianna Mary Boone Sep 2015

The Effects Of Parent-Adolescent Communication And Parenting Style On The Physical Activity And Dietary Behaviors Of Latino Adolescents, Dianna Mary Boone

USF Tampa Graduate Theses and Dissertations

The obesity epidemic among children and adolescents has been growing rapidly over the past 10 years, particularly in Latino children. Multiple researchers have found support for positive associations between parent-child communication and healthy nutrition and exercise behaviors. The present study examined the relations between parent-adolescent communication and parenting style and the dietary and exercise behaviors of Latino adolescents. The study included 79 adolescents between the ages of 13 and 18 years and their parents (100% are Latino). Correlation and hierarchical regression analyses were conducted to determine which parenting style and communication variables are significantly associated with adolescents’ dietary and physical …


The Relation Between Adiposity And Anxiety In Youth: Analysis Of Peer Victimization, Teasing, Sociocultural Influences, And Internalization Of Appearance Ideals As Explanatory Variables, Natasha L. Burke Jan 2015

The Relation Between Adiposity And Anxiety In Youth: Analysis Of Peer Victimization, Teasing, Sociocultural Influences, And Internalization Of Appearance Ideals As Explanatory Variables, Natasha L. Burke

USF Tampa Graduate Theses and Dissertations

The purpose of the current study was to examine putative mediators and moderators in the association between adiposity and anxiety in a sample of overweight and obese youth. In addition, anxiety was examined as a potential moderator between adiposity and health-related quality of life (HRQOL). Participants were youth (N = 137) between 8 and 17 years old (M = 13.09, SD = 2.61) and their legal caregivers recruited from four medical clinics affiliated with the University of South Florida. Youth were primarily overweight (28.5%) or obese (64.2%) and ethnically diverse. Data were analyzed by path analysis. Weight-related teasing significantly mediated …


Effects Of Occupational Stressors On Nurses’ Safety Performance And Well-Being: A Within-Individual Study, Xinxuan Che Jan 2015

Effects Of Occupational Stressors On Nurses’ Safety Performance And Well-Being: A Within-Individual Study, Xinxuan Che

USF Tampa Graduate Theses and Dissertations

Occupational stressors have been extensively studied as predictors of safety performance and employee well-being in previous research. However, many newly introduced organizational constructs that have the characteristics of an occupational stressor have rarely been studied as such, especially from a within-person perspective. The current study focused on three occupational stressors in relation to safety performance. Based on previous literature, I proposed that within individuals, compulsory citizenship behavior, illegitimate tasks, and interpersonal conflict at work as occupational stressors would have negative effects on employees well-being and safety performance through negative emotions (anger), job attitudes (job satisfaction and organizational commitment) and role …


Mediation And Moderation Analysis Of Nutrition, Inflammatory Biomarkers, And Cognition In Older Adults, Elizabeth Handing Jan 2015

Mediation And Moderation Analysis Of Nutrition, Inflammatory Biomarkers, And Cognition In Older Adults, Elizabeth Handing

USF Tampa Graduate Theses and Dissertations

Nutrition can be viewed as a modifiable factor related to maintaining and preserving health in older adults. Previous studies have found that nutritional factors can influence cognitive abilities, however few studies have examined macronutrients and micronutrients as they relate to cognitive functioning. Research has yet to examine the mechanisms related to nutrition, cognition and aging in an older adult population from a holistic and interactive perspective.

This dissertation examined three research questions to better understand the relationship between age, nutrition, cognition, and inflammatory biomarkers. First, is nutrition related to cognition beyond demographic factors? Do individual nutrients serve as mediators? Second, …


Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver Jan 2015

Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver

USF Tampa Graduate Theses and Dissertations

Research on addictive behavior has traditionally emphasized the role that primary reinforcing effects of drugs of abuse plays in the development and maintenance of dependence. However, contemporary behavioral economic theory and animal models of nicotine dependence suggest the need for greater attention to the impact that response to alternative rewards may have on smoking behavior. The present study sought to investigate the impact of nicotine withdrawal on self-report, behavioral and neural indices of motivation, immediate response to rewards and the capacity to learn and modify behavior in response to positive and negative feedback. Heavy smokers (n = 48) completed two …


Undergraduate College Students’ Attitudes About Internet-Based Mental Health Interventions, Kathleen Palmer Jan 2015

Undergraduate College Students’ Attitudes About Internet-Based Mental Health Interventions, Kathleen Palmer

USF Tampa Graduate Theses and Dissertations

Millennial-aged young adults, often referred to as “digital natives,” comprise the typical college-age population, and there has been a growing number college students at risk for mental health problems (Mowbray, Mandiberg, Stein, Kopels, Curlin, Megivern, Strauss, Collins & Lett, 2006; Eisenberg, Gollust, Golberstein & Hefner, 2007). Suicide is the second leading cause of death among college students (Suicide Statistics, 2014); however, their rate of utilizing mental heath counseling is decreasing. Providing the types of mental health services college students are likely to use can mitigate factors thought to impede their use (e.g., stigma, anonymity, confidentiality), as well as help improve …


Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon Jan 2015

Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon

USF Tampa Graduate Theses and Dissertations

Men who have sex with men (MSM) are at increased risk of anal cancer as a result of anal HPV infection. Routine HPV vaccination is recommended for all MSM up through age 26; however, vaccine uptake among this population is low. The Integrative Model of Behavioral Prediction (IM) was used to identify, describe, and explain psychosocial factors related to HPV vaccine decision-making for young MSM. A sequential mixed-methods approach consisting of semi-structured interviews, a quantitative survey, and a qualitative open-ended survey was used to address the following aims: (1) Determine salient outcome, normative, efficacy, and control beliefs related to HPV-vaccination …


Developing An Animal Model Of Polysubstance Abuse In Adolescence: The Role Of Nmda Receptors In Alcohol/Cocaine Reward, Adriana Rebecca Uruena-Agnes Nov 2014

Developing An Animal Model Of Polysubstance Abuse In Adolescence: The Role Of Nmda Receptors In Alcohol/Cocaine Reward, Adriana Rebecca Uruena-Agnes

USF Tampa Graduate Theses and Dissertations

Repeated exposure to drugs of abuse conditions individuals to anticipate the behavioral consequences of drug use specifically in the presence of a drug-associated context. In rodents, preferences and aversions for alcohol and cocaine have been conditioned; however, the mechanisms underlying the expression of these conditioned effects remain unknown. Given that alcohol and cocaine polysubstance abuse is prevalent in young individuals, with more than 50% of these polysubstance abusers reporting to be under the age of 21, it is important to understand the mechanisms contributing to the behavioral effects of alcohol and cocaine co-dependency. Aim 1 determined if age differentially impacted …


Effects Of Workplace Incivility On Nurses' Emotions, Well-Being, And Behaviors: A Longitudinal Study, Zhiqing Zhou Jul 2014

Effects Of Workplace Incivility On Nurses' Emotions, Well-Being, And Behaviors: A Longitudinal Study, Zhiqing Zhou

USF Tampa Graduate Theses and Dissertations

This dissertation used an experience sampling design to examine effects of experienced workplace incivility from three categories of organizational insiders (coworkers, supervisors, and physicians) and from organizational outsiders (patients and their visitors) on targets' emotions, burnout, physical symptoms, and their own uncivil behaviors toward each of the four groups of people. Data were collected from 75 nurses with each nurse responding to online surveys twice per week for 5 consecutive weeks. Results from hierarchical linear modeling showed that within individuals, negative emotions were positively associated with experienced workplace incivility (overall and source-specific), burnout was positively associated with overall workplace incivility …


Illness Perceptions Of Polycystic Ovary Syndrome, Elizabeth Baker Jun 2014

Illness Perceptions Of Polycystic Ovary Syndrome, Elizabeth Baker

USF Tampa Graduate Theses and Dissertations

Polycystic ovary syndrome (PCOS) is a chronic illness that affects approximately five million premenopausal women in the United States and is associated with significant cosmetic, reproductive, metabolic, and psychological consequences. Despite its prevalence, few studies have explored the lived experiences and illness perceptions of women living with PCOS. Identifying illness perceptions of women living with (WLW) PCOS is important, because mounting research suggests that a person's perceptions of their chronic illness and its management determine that person's coping behaviors (e.g., adherence, self-management) and, consequently, illness outcomes.

In this dissertation, the Common Sense Model (CSM) is used as a framework to …


Savor The Memory: A Reminiscence Exercise To Increase Positive Emotions And Reduce Depression Risk In Anxious Individuals, Bethany Morris May 2014

Savor The Memory: A Reminiscence Exercise To Increase Positive Emotions And Reduce Depression Risk In Anxious Individuals, Bethany Morris

USF Tampa Graduate Theses and Dissertations

A growing literature suggests that experiencing positive emotions provides psychological benefits (e.g., Coifman et al. 2007), and interventions increasing positive emotions may reduce depression risk (Geschwind et al., 2011). The present study tested whether reminiscence, a method of positive emotion savoring (Quoidbach et al., 2010), can mitigate depression risk by increasing positive emotions in an unselected sample and a subsample of at-risk anxious individuals. Female participants (n=336) were randomized to a reminiscence or control condition and asked to complete daily mental imagery exercises focusing on a positive memory (reminiscence) or a neutral laboratory memory (control) for one week. As expected, …


Evaluation Of Video Modeling To Teach Children Diagnosed With Asd To Avoid Poison Hazards, Shannon Eileen King May 2014

Evaluation Of Video Modeling To Teach Children Diagnosed With Asd To Avoid Poison Hazards, Shannon Eileen King

USF Tampa Graduate Theses and Dissertations

Accidental poisonings are one of the leading safety threats for young children, so it is important to teach children to avoid ingesting poisonous substances. Research has shown that behavioral skills training (BST) and in situ training (IST) are effective in teaching children safety skills to prevent gun play, abduction, and poison ingestion. However, little research on safety skills has been conducted with children with autism. Video modeling has been shown to be effective in teaching abduction prevention skills to children diagnosed with Autism Spectrum Disorder (ASD). The purpose of this study was to evaluate the effectiveness of video modeling to …


Exploring The Energy Link Between Emotion Regulation At Work And Health Behaviors, Ryan Christopher Johnson Mar 2014

Exploring The Energy Link Between Emotion Regulation At Work And Health Behaviors, Ryan Christopher Johnson

USF Tampa Graduate Theses and Dissertations

The present study explores the process through which the regulation of emotions at work, also known as emotional labor, depletes self-regulatory resources, specifically energy, and distally impacts health behaviors in the form of less physical activity and more unhealthy eating. Differences in relationships between two forms of emotional labor, surface acting and deep acting, as well as differences between psychological and physical energy depletion, are explored. Additionally, the roles of trait mindfulness and future temporal focus are examined as between-individual differences moderating the proposed relationships.

Multi-level analysis of daily diary data collected from participants (N = 108 participants) over ten …


Relationships Between Parenting Self-Efficacy And Distress In Parents With And Without Cancer, Julie Marie Cessna Jan 2014

Relationships Between Parenting Self-Efficacy And Distress In Parents With And Without Cancer, Julie Marie Cessna

USF Tampa Graduate Theses and Dissertations

Despite the relatively large number of parents with cancer, relatively little is known about the extent to which having cancer affects the parenting experience. Qualitative studies have identified issues and concerns that create distress among parents with cancer, but quantitative studies have yet to be conducted. Studies demonstrate that parents with cancer experience psychological distress, and that parenting self-efficacy is related to psychological distress among parents without cancer. However, no study to date has examined the relationships between parenting self-efficacy and psychological distress among parents with cancer. This study sought to address these gaps in the literature by comparing parents …


Illegitimate Tasks And Employee Well-Being: A Daily Diary Study, Erin Eatough Jan 2013

Illegitimate Tasks And Employee Well-Being: A Daily Diary Study, Erin Eatough

USF Tampa Graduate Theses and Dissertations

This dissertation focuses on an occupational stressor that has been recently introduced to the literature, illegitimate tasks, or tasks that seem unreasonable or unnecessary at work. Previous work has demonstrated the relationship between illegitimate tasks and a narrow set of discrete emotions as well as negative employee performance behaviors. The current research contributes to the literature by expanding the nomological network associated with illegitimate tasks and uses a rigorous daily diary methodology in a full-time working sample. It was expected that illegitimate tasks reduce state levels of self-esteem as well as other employee well-being indicators including anger, depressive mood, fatigue, …


Prevalence, Predictors, And Correlates Of Patient Concealment Of A Lung Cancer Diagnosis, Brian David Gonzalez Jan 2013

Prevalence, Predictors, And Correlates Of Patient Concealment Of A Lung Cancer Diagnosis, Brian David Gonzalez

USF Tampa Graduate Theses and Dissertations

Most cases of lung cancer have a commonly-understood behavioral etiology. Thus, individuals with lung cancer are often blamed for their illness by others and may therefore seek to avoid this blame by concealing their diagnosis from others. This study sought to determine the prevalence of diagnosis concealment, examine potential predictors of concealment, and test parts of a cognitive-affective-behavioral model of the effects of concealing a concealable stigma among individuals receiving treatment for lung cancer. With regard to predictors of concealment, it was hypothesized that concealment would be positively associated with male gender, introversion, and trait social anxiety and would be …


Exploring The Relationship Between Physical Activity And Everyday Cognitive Function In Older Adults: Within- And Between- Person Variability, Christine Haley Jan 2013

Exploring The Relationship Between Physical Activity And Everyday Cognitive Function In Older Adults: Within- And Between- Person Variability, Christine Haley

USF Tampa Graduate Theses and Dissertations

Research suggests that physical activity may play a role in preserving cognitive function in older adulthood. However, the exact nature, direction, and magnitude of observed associations remain unclear. The current study utilized a microlongitudinal design to repeatedly assess cognitive function and physical activity across five days. Two studies examined relationships between physical activity, physical fitness, and cognitive function among community-dwelling older adults. The first study examined associations between baseline performance in a measure of everyday cognition and multiple measures of physical activity and physical fitness. Bivariate analyses revealed that objectively measured physical activity of moderate-to-vigorous intensity, repeated chair stand time …


The Strong Black Woman, Depression, And Emotional Eating, Michelle Renee Offutt Jan 2013

The Strong Black Woman, Depression, And Emotional Eating, Michelle Renee Offutt

USF Tampa Graduate Theses and Dissertations

Abstract

Eighty percent of all black women are overweight or obese which can lead to greatly increased morbidity and mortality, increasing healthcare costs and loss of healthy years of life. While multiple factors may contribute to obesity in black women, the cultural persona of the Strong Black Woman (SBW), an ideology that promotes unflagging toughness and denial of self-needs, may be the basis for behaviors that contribute to steady state obesity in this group. The purpose of this study was to investigate the relationships between the SBW persona, depression, and emotional eating.

Two predominately black churches in Florida were approached …


Prenatal Stress, Depression, And Herpes Viral Titers, Pao-Chu Hsu Jan 2013

Prenatal Stress, Depression, And Herpes Viral Titers, Pao-Chu Hsu

USF Tampa Graduate Theses and Dissertations

Recent studies suggest that some cases of prenatal depression may be associated with reactivation of latent infections of the herpesvirus family. The possible relationships among stress, prenatal depression, and herpes viral reactivation in pregnancy are understudied and the molecular pathways such as the neuroimmune biogenic amine pathway are unidentified. Chronic stress shifts the T helper-1 cell (Th1) cytokine profile to a Th2 profile, which favors virus induced pathogenesis and survival. Pregnancy is also associated with a similar Th2 dominance. In non-pregnant individuals, exposure to psychological or physical stress may be associated with latent herpes viral reactivation and could result in …