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Articles 1 - 11 of 11

Full-Text Articles in Medicine and Health Sciences

Dynamics Of Apomyoglobin In The Α-To-Β Transition And Of Partially Unfolded Aggregated Protein, E. Fabiani, A. M. Stadler, D. Madern, M. M. Koza, M. Tehei, M. Hirai, G. Zaccai Oct 2008

Dynamics Of Apomyoglobin In The Α-To-Β Transition And Of Partially Unfolded Aggregated Protein, E. Fabiani, A. M. Stadler, D. Madern, M. M. Koza, M. Tehei, M. Hirai, G. Zaccai

Faculty of Science - Papers (Archive)

Changes of molecular dynamics in the α-to-β transition associated with amyloid fibril formation were explored on apo-myoglobin (ApoMb) as a model system. Circular dichroism, neutron and X-ray scattering experiments were performed as a function of temperature on the protein, at different solvent conditions. A significant change in molecular dynamics was observed at the α-to-β transition at about 55 ˚C, indicating a more resilient high temperature β structure phase. A similar effect at approximately the same temperature was observed in holo-myoglobin, associated with partial unfolding and protein aggregation. A study in a wide temperature range between 20 K and 360 K …


Biomarker Identification For Prostate Cancer Using An Efficient Feature Selection Algorithm, Vamsi Krishnam Raju Mantena Oct 2008

Biomarker Identification For Prostate Cancer Using An Efficient Feature Selection Algorithm, Vamsi Krishnam Raju Mantena

Electrical & Computer Engineering Theses & Dissertations

In recent years, there has been an increased interest in using protein mass spectrometry to identify biomarkers that discriminate diseased from healthy individuals. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathological processes, or pharmacological responses to a therapeutic intervention. Identifying biomarkers will be an important step towards disease characterization and patient management. One challenge of biomarker identification is how to handle the high dimensional mass spectral data. In this thesis, we applied an efficient feature selection algorithm to mass spectrometry data obtained from prostate tissue samples to identify prostate …


Unlv Magazine, Holly Ivy De Vore, Tony Allen, Barbara Cloud, Erin O'Donnell, Matthew K. Jacobsen, Gian Galassi, Michelle Mouton, Afsha Bawany, Shane Bevell Oct 2008

Unlv Magazine, Holly Ivy De Vore, Tony Allen, Barbara Cloud, Erin O'Donnell, Matthew K. Jacobsen, Gian Galassi, Michelle Mouton, Afsha Bawany, Shane Bevell

UNLV Magazine

No abstract provided.


Nuclear Energy, Steve Kraft Apr 2008

Nuclear Energy, Steve Kraft

Native American Forum on Nuclear Issues

Abstract:

-Why Nuclear Energy?

-The lesson of the last 20 years in U.S. electricity policy:

– Diversified fuel and technology portfolio is essential

– All fuels and technologies (nuclear, coal, natural gas, renewables, efficiency) have a legitimate role

-The challenge for the future:

– Preserving/restoring diversified portfolio

– Ensuring resource adequacy, particularly in competitive markets

-Expanded use of nuclear energy is part of the answer

– Integrated used fuel management supports nuclear competitiveness


Volume 01, Jessica Fields, Stephanie Neeley, Derek W. Hambright, Mary E. Lehman, Andrew R. Grzankowski, Zachary Johnson, Boone M. Prentice, Ashley M. Swandby, Victoria Morgan, Katie Williamson, Kristine G. Bender, Katelyn N. Romaine, D. Nicole Swann, Jessica Fox, Mike Mcateer, Alex Grabiec, Laura Nodtvedt, Nick Costa, Rachel Wolfe, Zack Dalton Apr 2008

Volume 01, Jessica Fields, Stephanie Neeley, Derek W. Hambright, Mary E. Lehman, Andrew R. Grzankowski, Zachary Johnson, Boone M. Prentice, Ashley M. Swandby, Victoria Morgan, Katie Williamson, Kristine G. Bender, Katelyn N. Romaine, D. Nicole Swann, Jessica Fox, Mike Mcateer, Alex Grabiec, Laura Nodtvedt, Nick Costa, Rachel Wolfe, Zack Dalton

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

Three Decades of Digging: Undergraduate Archeology at Longwood by Jessica Fields and Stephanie Neeley

Interactions of Allelopathy and Heat Stress in Plants by Derek W. Hambright and Mary E. Lehman

Inertial Electrostatic Confinement D-D Fusion Device: Construction and Simulation by Andrew R. Grzankowski

Shackled Nim by Zachary Johnson

Development of GC-MS and Chemometric Methods for the Analysis of Accelerants in Arson Cases by Boone M. Prentice

A Comparison of Image Analysis Methods in cDNA Microarrays by Ashley M. Swandby

Perceived Sexual Activity of Short and Long-Term Relationships by Victoria Morgan and Katie Williamson

Elderly …


In Situ Measurement Of Three-Dimensional Ion Densities In Focused Femtosecond Pulses, James Strohaber, Cornelis J. Uiterwaal Jan 2008

In Situ Measurement Of Three-Dimensional Ion Densities In Focused Femtosecond Pulses, James Strohaber, Cornelis J. Uiterwaal

Department of Physics and Astronomy: Dissertations, Theses, and Student Research

We image spatial distribution of xenon ions in the focus of a laser beam of ultrashort, intense pulses in all three dimensions, with a resolution of three by twelve microns in the two transverse directions. This allows for studying ionization processes without spatially averaging ion yields. Our in situ ion imaging is also useful to analyze focal intensity profiles and to investigate the transverse modal purity of tightly focused beams of complex light. As an example, the intensity profile of a Hermite-Gaussian beam mode HG recorded with ions is found to be in good agreement with optical images.


Sc Inbre: A Catalyst For Biomedical Research Development In South Carolina, Lucia A. Pirisi-Creek M.D, Scott Little, Ph.D. Jan 2008

Sc Inbre: A Catalyst For Biomedical Research Development In South Carolina, Lucia A. Pirisi-Creek M.D, Scott Little, Ph.D.

Journal of the South Carolina Academy of Science

No abstract provided.


A Call For A Statewide Bioinformatics Institute, John R. Rose Jan 2008

A Call For A Statewide Bioinformatics Institute, John R. Rose

Journal of the South Carolina Academy of Science

No abstract provided.


With The Help Of South Carolina Research Universities, Scra Demonstrates Leadership In Applied Research And Commercialization Within Sc, Bill Mahoney Jan 2008

With The Help Of South Carolina Research Universities, Scra Demonstrates Leadership In Applied Research And Commercialization Within Sc, Bill Mahoney

Journal of the South Carolina Academy of Science

No abstract provided.


Editorial, First Science And Policy Issue, Jscas Jan 2008

Editorial, First Science And Policy Issue, Jscas

Journal of the South Carolina Academy of Science

No abstract provided.


Cascading Infrastructure Failures: Avoidance And Response, George H. Baker, Cheryl J. Elliott Dec 2007

Cascading Infrastructure Failures: Avoidance And Response, George H. Baker, Cheryl J. Elliott

George H Baker

No critical infrastructure is self-sufficient. The complexity inherent in the interdependent nature of infrastructure systems complicates planning and preparedness for system failures. Recent wide-scale disruption of infrastructure on the Gulf Coast due to weather, and in the Northeast due to electric power network failures, dramatically illustrate the problems associated with mitigating cascading effects and responding to cascading infrastructure failures once they have occurred.

The major challenge associated with preparedness for cascading failures is that they transcend system, corporate, and political boundaries and necessitate coordination among multiple, disparate experts and authorities. This symposium brought together concerned communities including government and industry …