Medicine and Health Sciences Commons^™

Psilocybin With Acceptance And Commitment Therapy (Act) For The Treatment Of Social Anxiety Disorder (Sad), Aspen E. Allred

University Honors Theses

Social Anxiety Disorder (SAD) is a debilitating mental health condition characterized by an overwhelming fear and anxiety of social rejection that can lead to chronic patterns of social behavioral avoidance. Despite the existence of traditional efficacious treatments, a significant number of individuals either do not respond to treatment or experience a recurrence of symptoms over extended periods, spanning 10-12 years. Acceptance and Commitment Therapy (ACT), a form of acceptance-based behavioral therapy considered part of the "third wave" of cognitive behavioral therapies, has shown promising results in early studies, comparable to those of Cognitive Behavioral Therapy (CBT) that is considered the …

Metacognition, Social Cognition, And Mentalizing In Psychosis: Are These Distinct Constructs When It Comes To Subjective Experience Or Are We Just Splitting Hairs?, P. H. Lysaker, S. Cheli, G. Dimaggio, B. Buck, K. A. Bonfils, K. Huling, C. Wiesepape, J. T. Lysaker

Faculty Publications

Research using the integrated model of metacognition has suggested that the construct of metacognition could quantify the spectrum of activities that, if impaired, might cause many of the subjective disturbances found in psychosis. Research on social cognition and mentalizing in psychosis, however, has also pointed to underlying deficits in how persons make sense of their experience of themselves and others. To explore the question of whether metacognitive research in psychosis offers unique insight in the midst of these other two emerging fields, we have offered a review of the constructs and research from each field. Following that summary, we discuss …

The Efficacy Of Combination Of Psychosocial Interventions And Pharmacotherapeutic Intervention Compared To Standard Care In Patients Age 16-40 Diagnosed With Schizophrenia When Looking At Functional Capacity, Lisa Roth

Capstone Showcase

Introduction: Schizophrenia is a complex mental illness that arises from a combination of genetic factors, brain chemistry, substance use and environmental factors that affects the way a person behaves, thinks, and perceives. Schizophrenia has no cure, but it has several options for treatment including antipsychotic medications, psychotherapy, and education. Medication is frequently prescribed, and there is little evidence of how often psychotherapy is practiced to properly treat negative symptoms. The combination of these symptoms can have an impact on the functional capacity of an individual; this means that they may have less of an ability to proceed in a typical …

Barriers To Psychosocial Support And Quality Of Life For Patients With Inflammatory Bowel Disease: A Survey Study, Rebecca Lawrence, Md, Cuckoo Choudhary, Md

Department of Medicine Faculty Papers

Background: Psychological comorbidities are common among people with inflammatory bowel disease (IBD) and are associated with worse disease outcomes. Evidence-based psychotherapy is an effective means to increase psychosocial support. This study aimed to identify the barriers to attending psychotherapy.

Methods: This electronic survey study included a demographic, quality of life, and barriers to psychotherapy questionnaire. Quality of life was assessed using the Short Inflammatory Bowel Disease Questionnaire (SIBDQ). Barriers were assessed using the Perceived Barriers to Psychological Treatments scale (PBPT). Linear regression was used to identify participant characteristics associated with higher PBPT scores.

Results: One hundred eighty-seven …

Indicators Of Psychological Distress And Body Image Disorders In Female Patients With Breast Cancer, Helena Van Oers, Lourens Schlebusch

Journal of Mind and Medical Sciences

Breast cancer patients are vulnerable to elevated stress related to receiving the diagnosis, unfamiliar and invasive treatment, and coping with the side-effects of treatment, which may find various forms of expression. Another common feature of this patient population is body image dysphoria. Both the disease and treatment lead to impairments in physical appearance and general bodily functioning. This study aimed to explore the differential manifestations of stress and the nature of body image dysphoria within a sample of female breast cancer patients (n=80), compared to female patients with other sites of disease (n=80) in order to examine differences in the …

Psilocybin-Assisted Psychotherapy: Treating Depression And Anxiety With Mushrooms, Sofia Beck

Physician Assistant Studies | Student Articles

Depression and anxiety are debilitating mental health conditions that affect a large portion of the United States. Current pharmacological treatments for these disorders require daily administration, are associated with a number of side effects, and can be ineffective for some. Emerging evidence in novel treatment options may necessitate a shift toward how we treat these psychiatric disorders.

Studies involving the psychedelic serotonin agonist, psilocybin, are currently experiencing a resurgence as an alternative for patients who are unresponsive to traditional treatments. Clinical trials using psilocybin in combination with psychotherapy have demonstrated sustained reductions in depression and/or anxiety symptoms. When used in …

Evaluating The Effectiveness And Implementation Of Evidence-Based Treatment: A Multisite Hybrid Design., Jamile A Ashmore, Kirk W Ditterich, Claire C Conley, Melissa R Wright, Peggy S Howland, Kelly L Huggins, Jena Cooreman, Priscilla S Andrews, Donald R Nicholas, Lind Roberts, Larissa Hewitt, Joan N Scales, Jenny K Delap, Christine A Gray, Lynelle A Tyler, Charlotte Collins, Catherine M Whiting, Brittany M Brothers, Marlena M Ryba, Barbara L Andersen

Articles, Abstracts, and Reports

The gap between treatment development and efficacy testing to scaled up implementations of evidence-based treatment (EBT) is an estimated 20 years, and hybrid research designs aim to reduce the gap. One was used for a multisite study in cancer control, testing coprimary aims: (a) determine the feasibility and utility of a flexible EBT implementation strategy and (b) determine the clinical effectiveness of an EBT as implemented by newly trained providers. Therapists from 15 diverse sites implemented the biobehavioral intervention (BBI) for cancer patients (N = 158) as part of standard care. For implementation, therapists determined treatment format, number of …

The Quest For Self: Using Mandala Art In Reflective Practice Journaling, Kathleen Quinn

Comparative Woman

This article is a nexus of research, personal journaling reflections, and mandala creation from the authors own journals and focuses on the use of Mandalas as part of a reflective practice journaling process. Attention to mandala usage within reflective practice considering depth interiority, engaging and sharing with others. The authors approach to mandala construction is included followed by an exercise for observation and assessment of mandalas. The structure for reflective practice helps shape transformational leaders, using expressive arts, narratives in journaling. This transformational Discovery pathway and narrative exercises can be used for creating professional learning communities. This form of reflective …

Prevention Of Recurrent Affective Episodes Using Extinction Training In The Reconsolidation Window: A Testable Psychotherapeutic Strategy., Robert M Post, Robert Kegan

Psychiatry and Behavioral Sciences Faculty Publications

Stressors may initially precipitate affective episodes, but with sufficient numbers of recurrences, episodes can occur more autonomously. It is postulated the memory engram for these recurrent depressions moves from the conscious representational memory system to the unconscious habit memory system encoded in the striatum. If this were the case, cognitive behavior therapy targeted toward extinction of habit memories could be an effective maneuver for helping reverse the automaticity of affective episode recurrence. Extinction training in the reconsolidation window (which opens about 5 min to 1 h after active memory recall) can revise, reverse, or eliminate the long term memories associated …

Psychotherapy: Skills And Resilience Through Self-Knowledge, Gilana Finogenov

Family Medicine Clerkship Student Projects

At least 20% of all primary care visits are related to mental health. A limited number of patients are being referred to therapy, even though therapy is shown to be as effective as medication for disorders like depression and anxiety. A pamphlet was designed to explain what psychotherapy is to patients and to describe several common therapy modalities.

Low Vision Depression Prevention Trial In Age-Related Macular Degeneration: A Randomized Clinical Trial., Barry W. Rovner, Robin J Casten, Mark T Hegel, Robert W Massof, Benjamin E Leiby, Allen C Ho, William S Tasman

Department of Psychiatry and Human Behavior Faculty Papers

PURPOSE: To compare the efficacy of behavior activation (BA) + low vision rehabilitation (LVR) with supportive therapy (ST) + LVR to prevent depressive disorders in patients with age-related macular degeneration (AMD).

DESIGN: Single-masked, attention-controlled, randomized, clinical trial with outcome assessment at 4 months.

PARTICIPANTS: Patients with AMD and subsyndromal depressive symptoms attending retina practices (n = 188).

INTERVENTIONS: Before randomization, all subjects had 2 outpatient LVR visits, and were then randomized to in-home BA+LVR or ST+LVR. Behavior activation is a structured behavioral treatment that aims to increase adaptive behaviors and achieve valued goals. Supportive therapy is a nondirective, psychological treatment …

Improving Sexual Health In Men With Prostate Cancer: Randomised Controlled Trial Of Exercise And Psychosexual Therapies, Prue Cormie, Suzanne K. Chambers, Robert U. Newton, Robert A. Gardiner, Nigel Spry, Dennis R. Taaffe, David Joseph, M Akhlil Hamid, Peter Chong, David Hughes, Kyra Hamilton, Daniel A. Galvão

Research outputs 2014 to 2021

Background: Despite being a critical survivorship care issue, there is a clear gap in current knowledge of the optimal treatment of sexual dysfunction in men with prostate cancer. There is sound theoretical rationale and emerging evidence that exercise may be an innovative therapy to counteract sexual dysfunction in men with prostate cancer. Furthermore, despite the multidimensional aetiology of sexual dysfunction, there is a paucity of research investigating the efficacy of integrated treatment models. Therefore, the purpose of this study is to: 1) examine the efficacy of exercise as a therapy to aid in the management of sexual dysfunction in men …

On The Technical Error Of The Psychotherapist, Satoshi Tamiya M.D., Tetsuro Takahashi M.D.

Jefferson Journal of Psychiatry

The authors present a psychotherapy case where the therapist's countertransference-based technical error and his way of dealing with it remarkably influenced the course of treatment. The authors emphasize that appropriate training, including supervision and personal psychotherapy or psychoanalysis, is imperative, especially so that the beginning therapist can learn to manage countertranference appropriately. Since technical errors cannot always be avoided, it is important for the therapist to deal with them therapeutically, without feeling ashamed or guilty.

Case Report: Failure Of Group Therapy With Elderly Russian-Jewish Immigrants (An Exploratory Analysis), Gennady Berezkin M.D.

Jefferson Journal of Psychiatry

This paper is a description of an unsuccessful attempt to carry out group therapy with elderly Russian-Jewish immigrants.

An attempt was made to conduct group therapy following general principals of traditional psychotherapy with geriatric populations.

In the final analysis, we conclude that culturally based preconceptions toward psychotherapy, culturally based stereotypes of interpersonal relationships and culturally-based transference to the therapist were the primary reasons for the development of negative transference and resistance which culminated in the ultimate failure of group psychotherapy with this group of elderly immigrants.

The Role Of Group Psychotherapy In Psychiatric Residency Training, Shahbaz R. Khan M.D., Katherine A. Cowan M.D., Pedro Ruiz M.D.

Jefferson Journal of Psychiatry

Group psychotherapy has become a well-recognized treatment modality in the mental health field. Educationally, however, group psychotherapy has not reached the priority level it deserves. We described our experiences in using group psychotherapy as a training tool at the University of Texas at Houston. In describing our program, we used case illustrations to better demonstrate the richness of our training experiences. Group psychotherapy should be more extensively used in the training of tomorrow’s mental health professionals.

An Automated Internet Application To Help Patients With Bipolar Disorder Track Social Rhythm Stabilization., Daniel Z Lieberman, Susan Swayze, Frederick K Goodwin

Psychiatry and Behavioral Sciences Faculty Publications

This column describes a pilot study of a fully automated, Internet-based program that provides a key element of interpersonal and social rhythm therapy, a form of psychotherapy shown to be effective in the treatment of bipolar disorder when combined with mood-stabilizing medication. Participants (N=64) recorded the time they completed activities of daily living and their mood at the time of each entry. After 90 days they demonstrated a 31% increase in social rhythm stability and a small, though statistically significant, decrease in symptoms of abnormal mood. Internet-based programs can enhance access to a best practice in the management of bipolar …

Psychotherapy Or Pseudotherapy?, Lawson R. Wulsin, Md

Jefferson Journal of Psychiatry

What is psychotherapy? I wish I knew . Thick books and long talks still leave me wondering. Hours of patients and almost as many hours of supervision leave the question hanging. I know what ECT is and how to give a good trial of arnitryptiline, but I am never quite sure if what I am offering is true psychotherapy. Admittedly I am young and have only been wet for five years. But I have had one experience in my short time that put the question in perspective by putting it backwards, that is, what is notpsychotherapy, or what is pseudotherapy?

Oncolog, Volume 56, Number 03, March 2011, Bryan Tutt, Joe Munch

OncoLog MD Anderson's Report to Physicians (All issues)

• Glioblastoma Cure Remains Elusive Despite Treatment Advances: Aggressive surgery followed by radiation therapy and chemo-therapy offers hope of long-term survival for some patients with glioblastoma, but for most glioblastoma patients, the prognosis is poor
• Assessing and Addressing the Biological Effects of Stress in Cancer Patients: Stress has long been linked to cancer progression. But the precise mechanisms by which stress exacts its pro-tumor effects are not fully understood
• MD Anderson One of Four Centers to Test Cancer Cell Detection Chip: A new test that could monitor the effectiveness of cancer treatment
• HOUSE CALL: Yoga and Tai Chi: Two distinct disciplines …

Psychotherapy As A Treatment Modality For Psychiatric Disorders: Perceptions Of General Public Of Karachi, Pakistan, Abdul Mueed Zafar, Ali Jawaid, Hiba Ashraf, Ambreena Fatima, Rubina Anjum, Salah U. Qureshi

Department of Psychiatry

Background: Psychiatric disorders affect about 450 million individuals worldwide. A number of treatment modalities such as psychotropic medications, psychotherapy and electroconvulsive therapy can be used to treat these disorders. Attitudes of general public play a pivotal role in effective utilization of mental health services. We explored the perceptions of general public of Karachi, Pakistan regarding psychotherapy. Methods: A cross-sectional study was conducted in Karachi, Pakistan during July-August, 2008. A three-step sampling strategy and a structured questionnaire were employed to survey knowledge and perceptions of adult general public about psychotherapy. Descriptive statistics were used for baseline characteristics. Logistic regression models were …

Oncolog Volume 53, Number 06, June 2008, Karen Stuyck, Virginia M. Mohlere, David Stouter, David Jenkins

OncoLog MD Anderson's Report to Physicians (All issues)

• Psychotherapy Extends Cancer Care Beyond the Physical
• House Call: Understanding How Cancer Spreads
• DiaLog: Teaming Spiritual and Medical Care, by Rev. David Stouter, Chaplain, Department of Chaplaincy and Pastoral Education, and Rev. David Jenkins, Director, Department of Chaplaincy and Pastoral Education
• Radical Trachelectomy: A Fertility-Sparing Option for Invasive Cervical Cancer

Effects Of A Personified Guide On Adherence To An Online Program For Alcohol Abusers., Daniel Z Lieberman

Psychiatry and Behavioral Sciences Faculty Publications

The quality of the therapeutic alliance has robust effects on the outcome of psychotherapy and psychopharmacologic interventions. Automated behavioral health programs that are being developed to increase access to mental health treatment are administered in the absence of direct human participation, thereby precluding the development of a traditional therapeutic relationship. The aim of this study was to develop a personified guide designed to stimulate reactions similar to those experienced in a therapeutic relationship, and evaluate the effect of the guide on adherence to and satisfaction with an online alcohol use evaluation program. After completing a battery of four standard questionnaires …

Comparison Of Pretreatment Characteristics And Treatment Outcomes For Alcohol-, Cocaine-, And Multisubstance-Dependent Patients., Ashwin A. Patkar, Charles C. Thornton, Paolo Mannelli, Kevin P. Hill, Edward Gottheil, Michael J. Vergare, Stephen P. Weinstein

Department of Psychiatry and Human Behavior Faculty Papers

We investigated whether pretreatment characteristics and measures of outcome differed for alcohol-, cocaine-, and multisubstance-dependent patients receiving outpatient substance abuse treatment. One hundred and forty substance dependent individuals (32 alcohol, 76 cocaine, and 32 multisubstance) enrolled in a 12-week outpatient treatment program were compared across measures of addiction severity, personality, and treatment-readiness at admission. In-treatment, end-of-treatment and 9-month follow-up assessments of treatment outcome were then compared across the three groups. Outcome measures included reduction in problem severity, abstinence, retention, number of sessions attended, dropout, and counselor and patient ratings of treatment benefit. At admission, the multisubstance group had a higher …

Representations Of Therapists By Patients With Personality Disorders, Donna S. Bender, Barry A. Farber, Charles A. Sanislow, Ingrid R. Dyck, Jesse D. Geller, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

The purpose of this study was to investigate attributes of mental representations of therapists by patients with specific personality disorders (PDs), schizotypal (STPD), borderline (BPD), avoidant (AVPD), and obsessive-compulsive (OCPD), and a comparison group with Major Depressive Disorder and no PD (MDD). The Therapist Representation Inventory-II (TRI) measured characteristics of participants' extra-session thoughts about their therapists. Results showed that patients with STPD had the highest level of mental involvement with therapy outside the session, missing their therapists and wishing for friendship, while also feeling aggressive or negative. Patients with BPD exhibited the most difficulty in creating a benign image of …

Pre-Verbal Trauma, Dissociation And The Healing Process, Dorothy Dreier Scotten

Educational Studies Dissertations

This qualitative research study examines some of the ways in which the healing process takes place in adults who have experienced dissociation, and who have most likely been psychologically traumatized before full language development. The impact of early trauma on human cognitive, socio-emotional, and spiritual development are explored within the context of participant narratives in order to develop an understanding of what may be helpful in developing effective teaching strategies for clinical and teacher education. In-depth interviews were conducted with four adult persons who had been diagnosed with Dissociative Identity Disorder. All had histories of infant psychological trauma and all …

Oncolog, Volume 47, Number 10, October 2002, Sunni Hosemann, Mariann Crapanzano, Stephen P. Tomasovic Phd

OncoLog MD Anderson's Report to Physicians (All issues)

• A Natural Progression: M. D. Anderson Cancer Center Promotes the Study and Integration of Complementary Therapies
• New AJCC Staging System for Hepatocellular Carcinoma Reflects Patient Prognosis After Surgical Resection
• DiaLog: Complementary Medicine: Research, Education, and Communication, by Stephen P. Tomasovic, PhD, Professor of Molecular and Cellular Oncology and Vice President for Educational Programs
• House Call: Making the Cancer Journey Easier

Relation Of Therapeutic Alliance And Perfectionism To Outcome In Brief Outpatient Treatment Of Depression, David C. Zuroff, Sidney J. Blatt, Stuart M. Sotsky, Janice L. Krupnick, Daniel J. Martin, Charles A. Sanislow, Sam Simmens

Charles A. Sanislow, Ph.D.

Prior analyses of the National Institute of Mental Health Treatment of Depression Collaborative Research Program demonstrated that perfectionism was negatively related to outcome, whereas both the patient's perception of the quality of the therapeutic relationship and the patient contribution to the therapeutic alliance were positively related to outcome across treatment conditions (S. J. Blatt, D. C. Zuroff, D. M. Quinlan, & P. A. Pilkonis, 1996; J. L. Krupnick et al., 1996). New analyses examining the relations among perfectionism, perceived relationship quality, and the therapeutic alliance demonstrated that (a) the patient contribution to the alliance and the perceived quality of the …

Short And Long-Term Effects Of Medication And Psychotherapy In The Brief Treatment Of Depression: Further Analyses Of Data From The Nimh Tdcrp, Sidney J. Blatt, David C. Zuroff, Colin M. Bondi, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

Prior analyses of data from the NIMH sponsored Treatment for Depression Collaborative Research Program (TDCRP; e.g., I. Elkin, 1994) indicated greater reduction of symptoms at midtreatment (8th wk) with Imipramine (IMI-CM) than with Cognitive-behavioral therapy (CBT) and Interpersonal therapy (IPT), but no significant differences in symptom reduction among these 3 active treatments at termination. Current analyses of previously unanalyzed data from ratings by therapists, clinical evaluators, and 162 patients (mean age 35 yrs) at termination and at 18-mo follow-up also indicated no significant differences among these treatments in symptom reduction or ratings of current clinical condition. But significant treatment differences …

Vulnerability To Depression: Reexamining State Dependence And Relative Stability, David C. Zuroff, Sidney J. Blatt, Charles A. Sanislow, Colin M. Bondi, Paul A. Pilkonis

Charles A. Sanislow, Ph.D.

Treatment-related decreases in Dysfunctional Attitudes Scale (DAS; Weissman & Beck, 1978) scores have been interpreted as evidence that dysfunctional attitudes are state-dependent concomitants of depression. Data from the National Institute of Mental Health Treatment of Depression Collaborative Research Program were used to reexamine the stability of dysfunctional attitudes. Mean scores for Perfectionism, Need for Approval, and total DAS decreased after 16 weeks of treatment. However, test-retest correlations showed that the DAS variables displayed considerable relative stability. Structural equation models demonstrated that dysfunctional attitudes after treatment were significantly predicted by initial level of dysfunctional attitudes as well as by posttreatment depression. …

When And How Perfectionism Impedes The Brief Treatment Of Depression: Further Analyses Of The Nimh Tdcrp, Sidney J. Blatt, David C. Zuroff, Colin M. Bondi, Charles A. Sanislow, Paul A. Pilkonis

Charles A. Sanislow, Ph.D.

Perfectionism has previously been identified as having a significant negative impact on therapeutic outcome at termination in the brief (16-week) treatment of depression (S. J. Blatt, D. M. Quinlan, P. A. Pilkonis, & T. Shea, 1995) as measured by the 5 primary outcome measures used in the National Institute of Mental Health Treatment of Depression Collaborative Research Program (TDCRP). The present analyses of other data from the TDCRP indicated that this impact of perfectionism on therapeutic outcome was also found in ratings by therapists, independent clinical evaluators, and the patients and that this effect persisted 18 months after termination. In …

Oncolog, Volume 28, Number 02, April - June 1983, The University Of Texas Md Anderson Cancer Center, Donna R. Copeland Phd, Jorge R. Quesada Md, David A. Swanson, Antonio Trindade, Jordan U. Gutterman Md

OncoLog MD Anderson's Report to Physicians (All issues)

• Advanced Staging Procedures Promote Survival in Patients with Hodgkin's Disease
• Implantable Pump Allows Unlimited Treatment Without Extended Periods of Hospitalization
• Hypnotherapy Offers Relief from Discomfort and Anxiety for Receptive Pediatric Patients
• Leukocyte Interferon Potential Therapy for Patients with Metastatic Renal Cell Carcinoma