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Selected Works

2014

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Articles 151 - 155 of 155

Full-Text Articles in Medicine and Health Sciences

Developing A Risk Model For In-Hospital Adverse Events Following Implantable Cardioverter-Defibrillator Implantation.Pdf, Michael Mirro Dec 2013

Developing A Risk Model For In-Hospital Adverse Events Following Implantable Cardioverter-Defibrillator Implantation.Pdf, Michael Mirro

Michael Mirro, MD

Objectives: To better inform patients and physicians of the expected risk of adverse events, and
to assist hospitals’ efforts to improve the outcomes of patients undergoing implantable
cardioverter defibrillation (ICD) implantation, we developed and validated a risk model using data
from the National Cardiovascular Data Registry’s (NCDR®) ICD Registry™.

Background: ICDs prolong life in selected patients, but ICD implantation carries risk of
periprocedural complications.
Methods: We analyzed data from 240,632 ICD implantation procedures between 4/2010 and
12/2011 in the Registry. The population was divided into a derivation (70%) and a validation
(30%) cohort. Multivariable logistic regression was used to identify …

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How Are We Going To Live With Alzheimer's Disease?, Jason Karlawish Dec 2013

How Are We Going To Live With Alzheimer's Disease?, Jason Karlawish

Jason Karlawish

No abstract provided.

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A Tool To Assess The Signs And Symptoms Of Catheter-Associated Urinary Tract Infection: Development And Reliability, Thomas Blodgett, Sue Gardner, Nicole Blodgett, Lisa Peterson, Melissa Pietraszak Dec 2013

A Tool To Assess The Signs And Symptoms Of Catheter-Associated Urinary Tract Infection: Development And Reliability, Thomas Blodgett, Sue Gardner, Nicole Blodgett, Lisa Peterson, Melissa Pietraszak

Thomas Blodgett

The purpose of this pilot study was to determine the inter-rater reliability of four clinical manifestations of catheter-associated urinary tract infections (CAUTI) among hospitalized adults with short-term indwelling urinary catheters using a tool developed for this purpose: the CAUTI Assessment Profile (CAP). Study participants included 30 non-pregnant English-speaking adults, recruited from 2 community hospitals. Three nurses assessed each participant for fever, suprapubic tenderness, flank tenderness, and delirium using standardized techniques. Based on the generalized kappa statistic and 95% confidence intervals, there was evidence of strong inter-rater reliability for fever (kappa = 1.00, 0.793 – 1.207), suprapubic tenderness (kappa = 0.39, …

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Anticonvulsant Potencies Of The Enantiomers Of The Neurosteroids Androsterone And Etiocholanolone Exceed Those Of The Natural Forms, Dorota Zolkowska, Ashish Dhir, Kathiresan Krishnan, Douglas F. Covey, Michael A. Rogawski Dec 2013

Anticonvulsant Potencies Of The Enantiomers Of The Neurosteroids Androsterone And Etiocholanolone Exceed Those Of The Natural Forms, Dorota Zolkowska, Ashish Dhir, Kathiresan Krishnan, Douglas F. Covey, Michael A. Rogawski

Michael A. Rogawski

RATIONALE: Androsterone [(3α,5α)-3-hydroxyandrostan-17-one; 5α,3α-A] and its 5β-epimer etiocholanolone [(3α,5β)-3-hydroxyandrostan-17-one; 5β,3α-A)], the major excreted metabolites of testosterone, are neurosteroid positive modulators of GABA-A receptors. Such neurosteroids typically show enantioselectivity in which the natural form is more potent than the corresponding unnatural enantiomer. For 5α,3α-A and 5β,3α-A, the unnatural enantiomers are more potent at GABA-A receptors than the natural forms. OBJECTIVES: The aim of this study was to compare the anticonvulsant potencies and time courses of 5α,3α-A and 5β,3α-A with their enantiomers in mouse seizure models. METHODS: Steroids were administered intraperitoneally to male NIH Swiss mice 15 min (or up to 6 …

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The Use Of A Kiosk-Model Bilingual Self-Triage System In The Pediatric Emergency Department, Madhumita Sinha, Kai-Ning Khor, Ashish Amresh, David Drachman, Alan Frechette Dec 2013

The Use Of A Kiosk-Model Bilingual Self-Triage System In The Pediatric Emergency Department, Madhumita Sinha, Kai-Ning Khor, Ashish Amresh, David Drachman, Alan Frechette

Ashish Amresh

Streamlining the triage process is the key to improving emergency department (ED) workflow. Our objective was to determine if parents of pediatric ED patients in, low-literacy, inner-city hospital, who used the audio-assisted bilingual (English/Spanish) self-triage kiosk, were able to enter their child's medical history using a touch screen panel with greater speed and accuracy than routine nurse-initiated triage.

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