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Articles 181 - 181 of 181
Full-Text Articles in Medicine and Health Sciences
The Chemical State Of The Calcium Reacting In The Coagulation Of Blood, Armand J. Quick, Mario Stefanini
The Chemical State Of The Calcium Reacting In The Coagulation Of Blood, Armand J. Quick, Mario Stefanini
Biomedical Sciences Faculty Research and Publications
1. The widely accepted theory that calcium participates in the coagulation mechanism in the form of Ca++ and acts as a catalyst is not in accord with several important experimental findings:
(a) The anticoagulant action of sodium oxalate is much slower than the precipitation of ionized calcium as the oxalate salt.
(b) Sodium citrate begins to depress prothrombin activity at a concentration at which ionized calcium is still present. The inability of tricalcium phosphate to adsorb prothrombin from citrated plasma indicates that citrate forms a complex with prothrombin and it is postulated that prothrombin is …