Medicine and Health Sciences Commons^™

Relationship Between Gut Microbiota And Dementia, Saad Ahmed, Zackary Harris, Russell David Levi

Rowan-Virtua Research Day

This paper explores the complex relationship between gut microbiota, dietary habits, and dementia, focusing particularly on Alzheimer's disease (AD). Growing evidence suggests a significant link between the composition of gut bacteria, dietary choices, and susceptibility to dementia. Notably, individuals with dementia demonstrate a noticeable reduction in gut bacteria diversity, highlighting the crucial role of a balanced microbiome in maintaining cognitive health. Conversely, dietary preferences characterized by excessive consumption of processed foods and sugars are associated with an increased risk of dementia, emphasizing the critical influence of diet on shaping gut microbiota and subsequent neurocognitive outcomes. Importantly, dietary interventions featuring a …

Machine Learning As A Tool For Early Detection: A Focus On Late-Stage Colorectal Cancer Across Socioeconomic Spectrums, Hadiza Galadima, Rexford Anson-Dwamena, Ashley Johnson, Ghalib Bello, Georges Adunlin, James Blando

Community & Environmental Health Faculty Publications

Purpose: To assess the efficacy of various machine learning (ML) algorithms in predicting late-stage colorectal cancer (CRC) diagnoses against the backdrop of socio-economic and regional healthcare disparities. Methods: An innovative theoretical framework was developed to integrate individual- and census tract-level social determinants of health (SDOH) with sociodemographic factors. A comparative analysis of the ML models was conducted using key performance metrics such as AUC-ROC to evaluate their predictive accuracy. Spatio-temporal analysis was used to identify disparities in late-stage CRC diagnosis probabilities. Results: Gradient boosting emerged as the superior model, with the top predictors for late-stage CRC diagnosis being anatomic site, …

Multifactorial Exercise Intervention Decreases Falls Risk In High-Risk And Low-Risk Older Adults, Amanda Estep, Steven Morrison, Shane V. Caswell, Jatin P. Ambegaonkar, João R. Vaz, Nelson Cortes

Rehabilitation Sciences Faculty Publications

Background: Each year, 1 in 4 people over the age of 65 years of age will experience a fall. It is important to identify and address modifiable risk factors that are associated with falls in adults at high and low risk for falls.

Hypothesis: Falls risk improves in both high-risk and low-risk participants with the implementation of Stay Active and Independent for Life (SAIL).

Study Design: Cohort study.

Level of Evidence: Level 3.

Methods: Seventy-eight older adults (age, 70.9 ± 5.1 years) were included in this study and categorized into high risk and low risk for falling based on the …

Cell-Based Experimental Evidence To The Anti-Covid-19 Potential Of Ashwagandha And Honeybee Propolis Ingredients, Renu Wadhwa, Durai Sundar, Yoshiyuki Ishida, Keiji Terao, Sunil C. Kaul

Research Symposium

Background: The COVID-19 pandemic emerged in December 2019 by a novel strain of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has led to new endeavours in repurposing of existing drugs, anti-COVID-19 vaccine and drug development. Natural products, due to their general safety and wider availability, have attracted research and public attention. In this study, we report anti-COVID potential of compounds from honeybee propolis and Ayurvedic herb, Ashwagandha. Effect of active ingredients was studied on human cell surface receptors (ACE-2:Angiotensin Converting Enzyme-2/Spike protein and TMPRSS2:Transmembrane Protease Serine 2), critical for virus infection and virus main protease (Mpro, essential for virus replication), …

Effectiveness Of Intervention Studies Based On Diet And/Or Physical Activity In Treatment, Prevention, And Management Of Diabetes Among South Asians: A Systematic Review, Ishaan Arora

Theses and Dissertations

The purpose of this study was to describe diet and/or physical activity-based interventions and their control in cardiometabolic risk factors of diabetes for the South Asian (SA) population. A systematic review was conducted in accordance with the PRISMA guidelines. Seventeen randomized control trials meeting the inclusion criteria were included for analysis. Interventions with type-2 diabetic SA showed significant improvements in HbA1c% (4/5 studies), fasting blood glucose (3/4 studies), and postprandial glucose (2/2 studies). Interventions with at-risk/prediabetic and non-diabetic SA showed a modest change in overall outcomes, with significant change reported for post-prandial insulin (3/4 studies), BMI and weight (2/4 studies), …

Knowledge And Misconceptions Among Lebanese Community On Immunizations, Hala Ahmadieh, Tala Safa, Ihab Nahle, Yahya Obeid, Dalal Hariri, Etaf Rawass, Tala Kanaan, Ahmad Sabalbal

BAU Journal - Health and Wellbeing

Two centuries ago, immunization practices have become the greatest land mark in medical history as they significantly contributed to a decline in several major infectious diseases worldwide thus decreasing both the mortality and morbidity. Moreover, they have been able to eradicate small pox and eliminate poliomyelitis in most regions of the world. However, in recent years the general opinion towards vaccination began shifting due to the emergence of certain opposing views to it, questioning the vaccine's safety and efficacy. This study aims to shed light on the vaccination status in Lebanon by assessing the knowledge, attitude, awareness, and misconceptions among …

Towards A Globalised Vision Of Aquatic Competence, Rita F. Pinto, Juan Antonio Moreno Murcia

International Journal of Aquatic Research and Education

Human interaction with the aquatic environment has always taken different forms to meet the needs of pleasure, survival, therapy or performance. The diversity of existing aquatic spaces presents itself as a challenge, due to their variety, dynamism, unpredictability and unrepeatable conditions. These factors potentiate an infinite number of possibilities for human response in interaction with the aquatic environment, with aquatic competence being the one that will be able to sustain all types of interaction. Thus, the aim of the proposal has been to present a new approach to the contextualisation of aquatic competence. After a literature review on the concept …

Exploring Modern Trends And Prevention Strategies For Childhood Obesity: A Comprehensive Literature Review, Anya E. Bogen

Honors Theses

This literature review seeks to provide an overview of the current research on childhood obesity. The study examines the prevalence and causes of childhood obesity, including genetic, environmental, and behavioral factors. The review also discusses the health consequences associated with childhood obesity, such as the increased risk for chronic diseases and psychological and social problems. Additionally, the review explores the effectiveness of interventions designed to prevent childhood obesity, including individual lifestyle modifications, education from health practitioners and school programs, and global, national, and state programs to promote wellness. The literature review concludes that childhood obesity is a complex and multifactorial …

Access To And Utilization Of Primary Care: A Synthesis, Klaire M. Johnson

Kentucky Journal of Undergraduate Scholarship

Barriers to access and utilization of primary care affect nearly 9% of the nation’s population (USDHHS, n.d.a). These barriers are important to evaluate for members of the aging population due to increased need for health care as a result of chronic conditions and falls. Research indicates that access for the aging population is affected by a variety of factors, including: transportation, non-financial barriers, and internal factors. Issues surrounding current delivery of care, such as a workforce shortage of primary care physicians, have compounded the problem even further. While this issue has begun to be addressed through the Affordable Care Act, …

Survival Analysis And Prognostic Factors Of The Carcinoma Of Gallbladder, Zainab Feroz, Priyanka Gautam, Sonia Tiwari, Girish C. Shukla, Munish Kuma

Biological, Geological, and Environmental Faculty Publications

Background: The present study aims to evaluate the survival status of patients with gallbladder cancer (GBC) and explore the prognostic factors for the improvement and preventions.
Methods: The study consists of 176 patients with clinically diagnosed gallbladder cancer; the study was conducted between 2019 and 2021 registered at Kamala Nehru Memorial Cancer Hospital, Prayagraj, India. The survival rates were analyzed by the Kaplan-Meier method; survival rate difference was analyzed by log-rank test, prognosis factors; and hazard ratio for mortality outcomes was estimated using Cox regression method.
Results: The overall median survival time of patients was 5 months with the 1-year, …

The Emerging Epidemic Of Type 2 Diabetes And Obesity Amongst Young Children, Juliana Morales

Nursing | Senior Theses

Background:

In the past years childhood obesity has increased tremendously and currently ⅓ of children in the United States are obese today. Obesity and Type 2 Diabetes are illnesses that can later on lead to more severe health complications when as a child enters adulthood. Children who are obese have a greater risk of developing Type 2 diabetes, and currently more than 80% of children who already are diagnosed with Type 2 diabetes are obese. In school and often by health care providers we are told daily physical activity and healthy diet are the best ways to maintain optimal health, …

Psychophysiological Effects Of Increasing Awareness Of Nondual Consciousness In Young Adults With Depression And Anxiety, Milena Braticevic

CONSCIOUSNESS: Ideas and Research for the Twenty-First Century

Young adults increasingly suffer from anxiety and depression during the time of transition into adulthood. This research study examined the effects of increasing awareness of nondual consciousness in young adults who were experiencing various levels of anxiety and depression. The methodology was mixed-method and included four 1-hour group-based sessions over 4 weeks. Increasing awareness of nondual consciousness through educational, experiential, and behavioural components resulted in reduction in the average depression score from 19.4 (borderline clinical depression) to 10 (normal), and reduction in the average anxiety score from 12.7 (moderate anxiety) to 6.9 (mild). Participants reported increased mental, emotional, physical, and …

Webinars As A Tool For Increasing Awareness Of Diabetes Prevention And Management Programs, Cindy Jenkins, Carrie Durward, April Litchford, Catherine Hansen, Annette Prall, Caitlyn Jasumback

Outcomes and Impact Quarterly

Stakeholders sought to reduce the burden of preventable diabetes among adults in Utah via a “Food as Medicine” webinar series. The “Food as Medicine” webinar series sought to increase awareness of and enrollment in public diabetes programs. Evaluation results from the webinar series indicated an increase in awareness of diabetes programs and nutrition information needed to improve personal diabetes management.

Optimizing Prevention And Community-Based Management Of Severe Malnutrition In Children, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Zulfiqar A. Bhutta discusses prevention and treatment strategies for optimization of community-based management of severe acute malnutrition in children

Infectious Complications And Preventative Strategies Following Chimeric Antigen Receptor T-Cells (Car-T Cells) Therapy For B-Cell Malignancies, Alfadil Haroon, Ibrahim N. Muhsen, Muhammad Bilal Abid, Abdulwahab Albabtain, Ali Alahmari, Syed Osman Ahmed, Riad El Fakih, Mahmoud Aljurf

Hematology/Oncology and Stem Cell Therapy

Several chimeric antigen receptor T-cell constructs (CAR-T cells) are currently approved for the treatment of B-cell malignancies, including non-Hodgkin lymphoma and acute lymphoblastic leukemia. Additionally, multiple other products are being investigated and developed for other hematological malignancies and solid cancers. Patients receiving CAR-T cells are at increased risk of infectious complications that lead to increased morbidity and inferior mortality in these patients. In this review, we discuss the literature on the incidence and types of infection in patients in the early and late-phase after CAR-T cells infusion. Additionally, we summarize the current literature on prophylaxis against viral, bacterial, and fungal …

Lower Extremity Musculoskeletal Screening Tool Practices Among Athletic Trainers In Secondary School And Collegiate Settings, Megan B. Fowler, Elizabeth R. Neil, Cameron J. Powden

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Musculoskeletal (MSK) screening tools can allow athletic trainers (AT) to focus prevention efforts by providing patient risk information. The purpose of this study is to examine lower extremity MSK screening tool practices and perceptions of ATs in traditional settings. Methods: A cross-sectional online survey was distributed to 4,937 full- and part-time collegiate and secondary school ATs randomly selected by the NATA. MSK screening tools were grouped into 7 categories: Range of Motion (ROM), Strength, Balance, Drop and Jump Landing (D/J Land), Double- and Single-Leg Hopping (D/S Hop), Movement Quality (MQual), and Injury History (History). For each screening tool …

The Lifeguard Rescue Reporting System: Survey Results From A Collaborative Data Collection Method, William D. Ramos, Roy Fielding, Kristina R. Anderson, Peter G. Wernicki Md

International Journal of Aquatic Research and Education

Several water safety organizations have attempted to improve reporting regarding lifeguard actions in order to better understand the characteristics of successful, non-fatal rescues. In 2003, a collective effort initiated the Lifeguard Rescue Reporting System, an online survey distributed to lifeguards and facility managers across the United States and Canada to better understand rescue actions performed in pools/spas, water parks, and open water areas. After seven years of data collection, the online survey accumulated data reflecting 1,676 rescue actions, collecting information including location, victim characteristics and outcome, rescuer characteristics and strategies, and other general circumstances. Descriptive results indicated that at least …

Is The Acsm And Friend Metabolic Equations Valid For Assessing Cardiorespiratory Fitness Among 18-34 Aged Men? : Preliminary Results, Marc-Olivier Dugas, Laurie Simard, Tommy Chevrette, Martin Lavalliere

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 2: Issue 1, Article 2, 2021. Metabolic equations, such as ACSM and FRIEND, are used worldwide to indirectly measure the VO₂max in adults, but lack of accuracy seems to occur. 30 men of 18-34 years old performed a maximal incremental test on a treadmill during which direct VO₂max measurements was taken and then have been compared to ACSM and FRIEND metabolic equations. Point of application #1: Better evaluation and exercise prescription among athletic populations. Point of application #2: Act in prevention among sedentary and symptomatic populations. Point of application …

The Effect Of Warm-Up Protocols On The Occurrence Of Medial Tibial Stress Syndrome In High School Cross Country Athletes, Makayla Mack

Mahurin Honors College Capstone Experience/Thesis Projects

Medial Tibial Stress Syndrome (MTSS, i.e. shin splints) is among one of the most frequently reported running-related musculoskeletal injuries. Minimal research has investigated the prevention of MTSS with limited evidence supporting few preventative measures. The purpose of this study is to gain a better understanding of which method of warming up could yield the most promising results for the prevention of MTSS in high school cross country athletes and to use this information to further educate coaches and athletes on the most efficacious protocols to implement in the future. METHODS: Participants were recruited via communication with high school cross country …

Association Of Drowning Mortality With Preventive Interventions: A Quarter Of A Million Deaths Evaluation In Brazil, David Szpilman, Danielli B. Mello, Ana Catarina Queiroga, Rogerio Ferreira Emygdio Rfe

International Journal of Aquatic Research and Education

In 2015, drowning in Brazil was responsible for 6,043 deaths and was the second leading cause of death in children. Although several prevention strategies have been promoted to reduce drowning, most are still based on low levels of evidence. This study evaluated the effectiveness of prevention and water safety interventions in reducing drowning mortality. Data obtained from the National Mortality System for 36 years were split in two time periods to allow the comparison of drowning mortality numbers before and after implementation of SOBRASA’s drowning prevention and water safety programs and to check for any positive effects attributable to such …

Knowledge, Attitude And Practice For Healthcare Workers And Clinical Students About Infection Control Measures Awareness At Hospitals, Souhad Safadi, Esin Kavuran, Hanan Al Nuqiadan, Ahmad Tassi, Mirna Fawaz

BAU Journal - Health and Wellbeing

Healthcare-associated infections are a major global public health concern. Health care workers are on the front line of protecting themselves and clients from infection, through preventing the transmission of nosocomial infections and that is through the implementation of infection control measures. Therefore, the purpose of this study is to investigate the knowledge, attitude and practice of infection prevention among healthcare workers at Lebanese hospital. A descriptive cross-sectional research design was implemented in the study, where the sample included 240 participants (80 nurses, 80 medical lab, and 80 clinical students). Participants were surveyed using pre-tested self-administered questionnaire. The results showed that …

The Effect Of Educational Intervention On The Knowledge Of Nurses Regarding Catheter Indications And Catheter Associated Urinary Tract Infection Preventive Measures, Maryam Kbaysi, Esin Kavuran, Ahmad Tassi, Mirna Fawaz

BAU Journal - Health and Wellbeing

Catheter associated urinary tract infection (CAUTI) is the fourth leading cause of healthcare associated infections. The single most important predisposing factor for CAUTI is the insertion of urinary catheter. The aim of this study was to assess the effect of educational intervention on the knowledge of nurses regarding catheter indications and CAUTI preventive measures. A Pre-Post-test study design was utilized in this study which was conducted at two university hospitals one in Saida (South Lebanon) and the other one in Beirut in Lebanon. A self-reported questionnaire about catheter insertion and CAUTI prevention was used before and after the educational intervention, …

Midwife’S Role In The Mother-To-Child Transmission Prevention Program In Primary Health Care In Yogyakarta, Niken Meilani, Nanik Setiyawati, Sammy Onyapidi Barasa

Kesmas

Curing and eradicating Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) are to the core principles of the United Nations’ Sustainable Development Goals (SDGs). The incidence of HIV in the world remains high. Although midwives play a pivotal role in PMTCT implementation, the factors associated with midwives’ role in its implementation are not well understood. The aim of this study was to determine factors associated with midwives’ role in implementation of PMTCT. This study used a cross-sectional design. The subjects were 80 midwives at 14 primary health care in Yogyakarta City, Indonesia. The study was conducted from April to August 2017. …

Muscle Circumference And Tendon Width Correlation In Rotator Cuff Tears, Michael Marcinko, Michael Bamimore, Mark Ujevic

Research Day

Introduction: Rotator cuff tears are a common pathology presenting in much of the population especially those with repetitive overhead activity. There are many papers that looked at the supraspinatus as the most commonly torn rotator cuff muscle, however, there is a lack of research on the correlation between muscle morphology and injury. This was the framework for our anatomical study using cadavers, in which the circumference of the muscle bellies and tendon widths of the supraspinatus and infraspinatus muscles were measured.

Methods: 27 Cadavers provided by the Physician assistant program and first-year Osteopathic students in their respective anatomy …

Title: Efficacy Of A Food Parenting Intervention For Mothers With Low Income To Reduce Preschooler's Solid Fat And Added Sugar Intakes: A Randomized Controlled Trial., Jennifer O Fisher, Elena L Serrano, Gary D Foster, Chantelle N Hart, Adam Davey, Yasmeen P Bruton, Linda Kilby, Lisa Harnack, Karen J Ruth, Alexandria Kachurak, Hannah G Lawman, Anna Martin, Heather M Polonsky

Articles, Abstracts, and Reports

BACKGROUND: Few interventions have shown efficacy to influence key energy balance behaviors during the preschool years.

OBJECTIVE: A randomized controlled trial (RCT) was used to evaluate the efficacy of Food, Fun, and Families (FFF), a 12 week authoritative food parenting intervention for mothers with low-income levels, to reduce preschool-aged children's intake of calories from solid fat and added sugar (SoFAS).

METHODS: Mothers were randomly assigned to receive FFF (n = 59) or to a delayed treatment control (n = 60). The primary outcome was children's daily energy intake from SoFAS at the end of the 12 week intervention, controlling for …

Reducing Early Preterm Birth For 25 Cents A Day, Julie Quinlivan

Health Sciences Papers and Journal Articles

Editorial. No abstract available.

Field Testing Integrated Interventions For Schistosomiasis Elimination In The People's Republic Of China: Outcomes Of A Multifactorial Cluster-Randomized Controlled Trial, Gail M. Williams, Yue-Sheng Li, Darren J. Gray, Zheng-Yuan Zhao, Donald A. Harn, Lisa M. Shollenberger, Sheng-Ming Li, Xinglin Yu, Zeng Feng, Jia-Gang Guo, Jie Zhou, Yu-Lan Dong, Yuan Li, Biao Guo, Patrick Driguez, Marina Harvie, Hong You, Allen G. Ross, Donald P. Mcmanus

Biological Sciences Faculty Publications

Despite significant progress, China faces the challenge of re-emerging schistosomiasis transmission in currently controlled areas due, in part, to the presence of a range of animal reservoirs, notably water buffalo and cattle, which can harbor Schistosoma japonicum infections. Environmental, ecological and social-demographic changes in China, shown to affect the distribution of oncomelanid snails, can also impact future schistosomiasis transmission. In light of their importance in the S. japonicum, lifecycle, vaccination has been proposed as a means to reduce the excretion of egg from cattle and buffalo, thereby interrupting transmission from these reservoir hosts to snails. A DNA-based vaccine (SjCTPI) …

Postpartum Depression: Prevention And Multimodal Therapy, Anca Daniela Stanescu, Denisa Oana Balalau, Liana Ples, Stana Paunica, Cristian Balalau

Journal of Mind and Medical Sciences

A woman goes through many biological (hormonal, physical), psychological (emotional), and socio-cultural changes during pregnancy. Furthermore, changes also occur in the mother's familial and interpersonal world after childbirth. While some mothers have positive emotions at birth, such as joy and pleasure, others complain of negative experiences varying from sadness and depression to psychosis. Thus, the risk of depression is higher for women during the postpartum period, having a tendency to decrease in most cases over the first 2 weeks after delivery. Unfortunately, this favorable evolution does not happen in about 1 in 4-7 women, who develops postpartum depression. Postpartum depression …

Interventions For Afterschool Programs To Decrease The Likelihood Of Childhood Obesity, Anna R. Boyd, Lauren E. Hendricks, Elexus T. Morton, Kayleigh S. Phillips, Corie Vanarsdale, Msn

Nursing Undergraduate Work

This systematic research review (SRR) looked at the epidemic of childhood obesity and subsequent complications. Afterschool programs (ASPs) were targeted as a key area where children spend many hours each day and, therefore, an ideal place for obesity interventions. The purpose of this SRR was to search the current benefits ASPs can have on decreasing the risk and prevalence of childhood obesity and to answer the research question, "What are nursing interventions within ASPs that decrease the risk of obesity in children in the United States of America?" Childhood obesity influences nurses in many areas, including inpatient hospitals, schools, and …

The Effect Of Tackling Training On Head Accelerations In Youth American Football, Eric Schussler, Richard J. Jagacinski, Susan E. White, Ajit M. Chaudhari, John A. Buford, James A. Onate

Rehabilitation Sciences Faculty Publications

Background: Many organizations have introduced frameworks to reduce the incidence of football related concussions through proper equipment fitting, coach education, and alteration of tackling technique.

Purpose: The purpose of this study was to examine the effects of training in a vertical, head up tackling style on the number of head accelerations experienced while tackling in a controlled laboratory situation. The authors hypothesized that training in a head up tackling technique would reduce the severity of head acceleration experienced by participants.

Design: Controlled Laboratory Study.

Methods: Twenty-four participants (11.5 ± 0.6 years old, 60.5 ± 2.2 in, 110 ± 18.4 lbs.) …