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Full-Text Articles in Medicine and Health Sciences
Functional Characterization Of A High-Throughput In Vitro Model To Predict Faecal Microbiota Transplantation (Fmt) Donor Success, Catherine M. Andary
Functional Characterization Of A High-Throughput In Vitro Model To Predict Faecal Microbiota Transplantation (Fmt) Donor Success, Catherine M. Andary
Undergraduate Student Research Internships Conference
Faecal microbiota transplantation (FMT) involves the administration of donor faecal matter to a diseased recipient with the goal of remodeling the host microbiome to provide health benefits. In recent years, FMT has emerged as a potential therapy for a variety of microbiome-associated diseases such as atherosclerosis. Trimethylamine (TMA) is an atherosclerosis-linked metabolite generated by the gut microbiota from dietary precursors which is then oxidized to trimethylamine N-oxide (TMAO) by the liver, contributing to increased gut permeability. It has been shown that FMT may alter or restore the gut microbiome of recipients to reduce plasma TMAO levels. Despite its potential, the …
Analysis Of The Gut-Brain Axis In Aging: Implications In Alzheimer Disease, Molly Martin, Mary Austin, Denah Appelt
Analysis Of The Gut-Brain Axis In Aging: Implications In Alzheimer Disease, Molly Martin, Mary Austin, Denah Appelt
Research Day
The gut microbiome is comprised of the shared genome of the trillions of microorganisms residing in the gastrointestinal ecosystem. The interaction between the host and its gut microbiome, the Gut-Bran Axis (GBA), is a complex relationship whose management could prove critical to preventing or treating not only various gut disorders, like irritable bowel syndrome (IBS) or behavioral health disorders such as general depression and anxiety, but also central nervous system (CNS) disorders, such as Alzheimer's (AD) and Parkinson's (PD) diseases. The purpose of this review is to summarize what is currently known about the gut microbiome, how it is connected …