Medicine and Health Sciences Commons^™

Optimizing The Design And Potency Of Diterpenic Acid Derivatives To Improve Cell Membrane Permeability And Hsp27 Targeting Characteristics, Aicha Quamine

Undergraduate Research Posters 2015

Heat shock protein 27 (Hsp27) acts as a protective protein allowing it to play an integral role in aiding cancer cell resistance. Stress-induced Hsp 27 overexpression aids in the stabilization of partially denatured proteins to establish protein refolding resulting in thermotolerance, inhibition of apoptosis, cytoprotection, etc. As a result of rapid proliferation and general instability, cancer cells exhibit increased dependency on the support of Hsp 27 and it’s chaperone proteins, therefore generating an ideal target for anticancer therapy. Copalic acid, a clerodane diterpenoid, has already been confirmed in effective chaperone inhibition and antiproliferative synergistic effect. We hypothesize that by optimizing …

Dual Stimuli Response Frequency And Stimulus Choice Of The African Clawed Frog, Xenopus Laevis, When Presented With Two Stimuli, Mingo Rolince, Heidi Pignolet, Alexa Hoy

Undergraduate Research Posters 2015

This preliminary study examines responses of African Clawed Frogs to simultaneous presentation of two stimuli. Frogs were tested in a round arena with water 4 cm deep. Four stimulus rods driven via computer-controlled stepper motors were concealed in a screen suspended above the water. These rods could present a lateral line stimulus, a visual stimulus, or a combination of both. Overall, reactions and no reactions were evenly distributed--51.1% and 48.9%, respectively. Frogs responded more frequently to rostral than caudal stimuli (chi-squared 20.8, df=11, p < 0.04). Frogs reacted more to stimuli between -90° and 90°. Turn angle depended linearly on stimulus angle (e.g., Turn angle = 0.44 + 0.64 x Stimulus angle; pslope < 0.0001; R2adj = 69.5%). (The distributions of stimulus angles appear slightly skewed as often the same stimulus rod was retested after the frog responded and partially oriented towards it, prompting a second test with smaller angles.) Two stimuli did not elicit more responses than one stimuli (P=0.25). The frogs’ choice of stimulus depended primarily on stimulus proximity and angle, not stimulus type. When presented with two stimuli, the frog chose the nearer stimulus and the more rostral stimulus (p < 0.0001). The largest factor in predicting the frog’s choice of stimuli seems to be the linear distance from the stimuli to the frog.

Enhancement Of Solar Energy Conversion In Bio-Derived Cells Via Side Selective Modification Of Photosystem I, Uchechukwu Obiako, Evan Gizzie

Undergraduate Research Posters 2015

Deleterious effects of some methods used to harness energy from the environment today have garnered the exploration of safer and more reliable options, specifically solar energy conversion. Current solar cell technology has yielded quantum efficiencies commonly in the range of 10-20% but is limited by extensive processing methods, high cost, and need for rare materials. However, bio-derived solar cells containing Photosystem I (PSI) address these problems as PSI is highly abundant, very efficient, and low-cost. PSI acts as a biomolecular photodiode through rapid photoexcited charge separation, making it very promising for use as an integral element in solar cells. To …

Investigating Rhoptry Gene Conservation Between Plasmodium Yoelii And Plasmodium Falciparum Using The Polymerase Chain Reaction For Dna Amplification, Brooke Burkhalter

Undergraduate Research Posters 2015

In order to obtain a tangible basis for vaccine targets, it is crucial to understand the role of proteins at the site of invasion. In previous study, 27 novel rhoptry proteins were identified by MudPIT analysis and immunoelectron microscopy. In this investigation, the conservation of rhoptry genes between Plasmodium yoelii and Plasmodium falciparum was assessed. From the previously identified rhoptry genes, 14 were investigated with the orthologues/paralogues of the Plasmodium falciparum, Plasmodium yoelii, Plasmodium chabaudi, and Plasmodium berghei. Also, primers designed for the 14 Plasmodium yoelli rhoptry genes were used to test DNA amplification with the PCR. Amplification of Plasmodium …

Cultural Differences In Coping And Depression Between Individuals Of Middle-Eastern And Non-Arab Backgrounds, Khadeja Najjar

Undergraduate Research Posters 2015

The Middle Eastern (Arab) demographic is a growing, yet neglected cultural group in mental health research. While Arabs are more predisposed to depression than other ethnic groups in US, little is known about mechanisms that account for this risk. One set of mechanisms may be the use of ineffective (maladaptive) coping or insufficient use of effective (adaptive) coping responses, which are robust predictors of depression in US samples, but virtually unexamined in Arabs. Further, the effect of a coping is influenced by culture, which, for Arabs, may change as a function of acculturation. Thus, the present study aimed to examine …

Normalizing For Noise Removal From Electrocardiogram Signals, Dominique Diamond Brooks, Daniel J. Simon

Undergraduate Research Posters 2012

Electrocardiography (ECG) measures the electrical impulse of the heart over time using electrodes that attached to the body. Designing a computational program using a synthetic ECG to test Normalized Least Mean Square (NLMS) filter serves as a basis to remove noise from the signal.

2011 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Mark Tebeau

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Mark Tebeau was the guest speaker

2009 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Michael Schwartz Ph.D.

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Michael Schwartz was the honored guest.

2008 Scholars And Artists Bibliography, Rajshehkar G. Javalgi Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Rajshekhar Javalgi was the guest speaker.

2007 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Joanne E. Goodell Ph.D.

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Joanne Goodell was the guest speaker.

2006 Scholars And Artists Bibliography, Daniel J. Simon, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Dan Simon was the guest speaker.

2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr, Steve Slane was the guest speaker.

2004 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

2003 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

2002 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

2001 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1999 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1998 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1997 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1994 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1992 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1991 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

The Gamut: A Journal Of Ideas And Information, No. 32, Spring 1991, Cleveland State University

The Gamut Archives

CONTENTS OF ISSUE NO. 32, SPRING, 1991

Editorial

Louis T. Milic: The Cynic’s New Word Book, 2

Jane Ware: The Bones of Fort Laurens, 4

Excavating Ohio’s only Revolutionary War fort

Lawrence Martin: The Pickwickian Syndrome, 12

A deadly combination of obesity and too shallow breathing

Donald Dewey: Let’s Reorganize Major League Sports!, 25

Shouldn’t major league membership be based on performance?

Barbra Cunliffe Singleton: Walking the Wrong Way Around the Monastery, 31

Tibet’s cultural heritage is being erased under Chinese rule

John A.C. Greppin: The Language of the Babylonians and Assyrians, 37

Deciphering …

1990scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

1989 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti