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Capsular Hyaluronic Acid-Mediated Adhesion Of Pasteurella Multocida To Turkey Air Sac Macrophages, Ingrid M. Pruimboom, Richard B. Rimler, Mark R. Ackermann, Kim A. Brogden
Capsular Hyaluronic Acid-Mediated Adhesion Of Pasteurella Multocida To Turkey Air Sac Macrophages, Ingrid M. Pruimboom, Richard B. Rimler, Mark R. Ackermann, Kim A. Brogden
Mark R. Ackermann
Serogroup A strains of Pasteurella multocida, the major cause of fowl cholera, are resistant to phagocytosis in nonimmunized birds. Adherence studies with a capsulated strain of P multocida (serotype A:3) and turkey air sac macrophages in culture showed that the bacteria were capable of adhering in large numbers to the macrophages but were not internalized. A noncapsulated variant of the bacteria (serotype -:3) showed little or no adherence and was not internalized. These data indicated that the adhesive properties were caused by the presence of a capsule on the bacteria. The role of capsular hyaluronic acid in adherence to macrophages …
Comparison Of The Effect Of Different Opsonins On The Phagocytosis Of Fluorescein-Labeled Staphylococcal Bacteria By Chicken Heterophils, Claire B. Andreasen, James R. Andreasen Jr., Anita E. Sonn, Julie A. Oughton
Comparison Of The Effect Of Different Opsonins On The Phagocytosis Of Fluorescein-Labeled Staphylococcal Bacteria By Chicken Heterophils, Claire B. Andreasen, James R. Andreasen Jr., Anita E. Sonn, Julie A. Oughton
Claire B. Andreasen
Heterophil phagocytosis of fluorescein-labeled staphylococcal bacteria was analyzed by flow cytometry. Opsonization with two types of normal pooled sera and staphylococcal antisera significantly increased bacterial phagocytosis compared to samples without an opsonin. The staphylococcal antisera did not significantly increase bacterial phagocytosis compared to the normal pooled sera. Opsonization appears to increase bacterial phagocytosis but specific antisera may not increase phagocytosis beyond that caused by pooled normal sera.