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Full-Text Articles in Medicine and Health Sciences

Transcriptome Sequencing Of The Blind Subterranean Mole Rat, Spalax Galili: Utility And Potential For The Discovery Of Novel Evolutionary Patterns, Assaf Malik, Abraham Korol, Sariel Hubner, Aaron Avivi, Alvaro Hernandez, Jyothi Thimmapuram, Shahjahan Ali, Mark Bond, Fabian Glaser, Arnon Paz Aug 2011

Transcriptome Sequencing Of The Blind Subterranean Mole Rat, Spalax Galili: Utility And Potential For The Discovery Of Novel Evolutionary Patterns, Assaf Malik, Abraham Korol, Sariel Hubner, Aaron Avivi, Alvaro Hernandez, Jyothi Thimmapuram, Shahjahan Ali, Mark Bond, Fabian Glaser, Arnon Paz

Cyber Center Publications

The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of S. ehrenbergi. cDNA pools from muscle and brain tissues isolated from animals exposed to hypoxic and normoxic conditions were sequenced using Sanger, GS FLX, and GS FLX Titanium technologies. Assembly of the sequences yielded over 51,000 isotigs with homology to ~12,000 mouse, rat or human genes. Based on these results, it was …


Orchardgrass (Dactylis Glomerata L.) Est And Ssr Marker Development, Annotation, And Transferability., B.S. Bushman, S.R. Larson, M Tuna, M.S. West, A.G. Hernandez, D Vullaganti, G Gong, J.G. Robbins, K. B. Jensen, Jyothi Thimmapuram Apr 2011

Orchardgrass (Dactylis Glomerata L.) Est And Ssr Marker Development, Annotation, And Transferability., B.S. Bushman, S.R. Larson, M Tuna, M.S. West, A.G. Hernandez, D Vullaganti, G Gong, J.G. Robbins, K. B. Jensen, Jyothi Thimmapuram

Cyber Center Publications

Orchardgrass, or cocksfoot [Dactylis glomerata (L.)], has been naturalized on nearly every continent and is a commonly used species for forage and hay production. All major cultivated varieties of orchardgrass are autotetraploid, and few tools or information are available for functional and comparative genetic analyses and improvement of the species. To improve the genetic resources for orchardgrass, we have developed an EST library and SSR markers from salt, drought, and cold stressed tissues. The ESTs were bi-directionally sequenced from clones and combined into 17,373 unigenes. Unigenes were annotated based on putative orthology to genes from rice, Triticeae grasses, other Poaceae, …


Identification And Analysis Of Common Bean (Phaseolus Vulgaris L.) Transcriptomes By Massively Parallel Pyrosequencing, Venu Kalavacharla, Zhanji Liu, Blake C. Meyers, Jyothi Thimmapuram, Kalpalatha Melmaiee Jan 2011

Identification And Analysis Of Common Bean (Phaseolus Vulgaris L.) Transcriptomes By Massively Parallel Pyrosequencing, Venu Kalavacharla, Zhanji Liu, Blake C. Meyers, Jyothi Thimmapuram, Kalpalatha Melmaiee

Cyber Center Publications

Common bean (Phaseolus vulgaris) is the most important food legume in the world. Although this crop is very important to both the developed and developing world as a means of dietary protein supply, resources available in common bean are limited. Global transcriptome analysis is important to better understand gene expression, genetic variation, and gene structure annotation in addition to other important features. However, the number and description of common bean sequences are very limited, which greatly inhibits genome and transcriptome research. Here we used 454 pyrosequencing to obtain a substantial transcriptome dataset for common bean.


Privacy-Preserving Assessment Of Location Data Trustworthiness, Chenyun Dai, Fang-Yu Rao, Gabriel Ghinita, Elisa Bertino Jan 2011

Privacy-Preserving Assessment Of Location Data Trustworthiness, Chenyun Dai, Fang-Yu Rao, Gabriel Ghinita, Elisa Bertino

Cyber Center Publications

Assessing the trustworthiness of location data corresponding to individuals is essential in several applications, such as forensic science and epidemic control. To obtain accurate and trustworthy location data, analysts must often gather and correlate information from several independent sources, e.g., physical observation, witness testimony, surveillance footage, etc. However, such information may be fraudulent, its accuracy may be low, and its vol-
ume may be insufficient to ensure highly trustworthy data. On the other hand, recent advancements in mobile computing and positioning systems, e.g., GPS-enabled cell phones, highway sensors, etc., bring new and effective technological means to track the location of …


Prox-Rbac: A Proximity-Based Spatially Aware Rbac, Michael Kirkpatrick, Maria Luisa Damiani, Elisa Bertino Jan 2011

Prox-Rbac: A Proximity-Based Spatially Aware Rbac, Michael Kirkpatrick, Maria Luisa Damiani, Elisa Bertino

Cyber Center Publications

As mobile computing devices are becoming increasingly dominant in enterprise and government organizations, the need for fine-grained access control in these environments continues to grow. Specifically, advanced forms of access control can be deployed to ensure authorized users can access sensitive resources only when in trusted locations. One technique that has been proposed is to augment role-based access control (RBAC) with spatial constraints. In such a system, an authorized user must be in a designated location in order to exercise the privileges associated with a role. In this work, we extend spatially aware RBAC systems by defining the notion of …