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Full-Text Articles in Medicine and Health Sciences

Baseline Mmp Expression In Periapical Granuloma And Its Relationship With Periapical Wound Healing After Surgical Endodontic Treatment, Muhammad Adeel Ahmed, Muhammad Faraz Anwar, Khalid Ahmed, Marziya Aftab, Fizza Nazim, Muhammad Furqan Bari, Mohammed Mustafa, Fahim Vohra, Ali Alrahlah, Muhammad Nouman Mughal, Syed Hani Abidi Nov 2021

Baseline Mmp Expression In Periapical Granuloma And Its Relationship With Periapical Wound Healing After Surgical Endodontic Treatment, Muhammad Adeel Ahmed, Muhammad Faraz Anwar, Khalid Ahmed, Marziya Aftab, Fizza Nazim, Muhammad Furqan Bari, Mohammed Mustafa, Fahim Vohra, Ali Alrahlah, Muhammad Nouman Mughal, Syed Hani Abidi

Department of Biological & Biomedical Sciences

Background: Matrix metalloproteinases (MMPs) catalyzes the degradation of the extracellular matrix components and have a major role in many physiological processes including wound healing. In the current study, we examined the correlation of baseline MMPs 1, 2, 7, and 9 expressions with periapical wound healing after surgical endodontic treatment.
Methods: 27 patients aged between 15 and 57 years presenting with chronic apical periodontitis or chronic apical abscess of an anterior tooth with previously attempted or failed root canal treatment were included in this study. During surgical endodontic treatment, tissue from the periapical lesion sample was collected and used for gross …


Soft Tissue Profile Response In Extraction Versus Non-Extraction Orthodontic Treatment, Munizeh Khan, Mubassar Fida Jul 2010

Soft Tissue Profile Response In Extraction Versus Non-Extraction Orthodontic Treatment, Munizeh Khan, Mubassar Fida

Section of Dental-Oral Maxillofacial Surgery

Objective: To compare changes occurring in the soft tissue profile with orthodontic treatment in extraction versus nonextraction cases, and to determine the hard and soft tissue parameters that show significant correlations to understand the factors influencing the response to tooth movement. Study Design: Quasi-experimental. Place and Duration of Study: Dental Section, The Aga Khan University Hospital, Karachi, from 2005 to 2008. Methodology: Pre- and post-treatment lateral cephalographs of 34 subjects were assessed. For half of the patients (n=17), treatment included the extraction of 4 premolars, whereas the other half were treated by the non-extraction approach. Incisal and soft tissue effects …


Frequency And Distribution Of Endodontically Treated Teeth, Hina Ahmed, Durr E. Sadaf, Munawar Rahman Oct 2009

Frequency And Distribution Of Endodontically Treated Teeth, Hina Ahmed, Durr E. Sadaf, Munawar Rahman

Section of Dental-Oral Maxillofacial Surgery

Objective: To determine the distribution and pattern of carious teeth involvement in permanent teeth requiring endodontic treatment. Study Design: Cross-sectional study. Place and Duration of Study: Dental Section of The Aga Khan University Hospital, Karachi, from September 2004 to March 2005. Methodology: Data was collected from the dental records of patients. Tooth was the unit of evaluation. Variables studied were demographics, tooth type, etiology of endodontic treatment and pattern of caries involvement. Data was analyzed using chi-square test and Fischer’s exact test. Results: The total number of patients was 190; total number of teeth involved were 235. Females had more …