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Full-Text Articles in Medicine and Health Sciences
The Icr Mouse: An Mhc Matched Control For The Non-Obese Diabetic Mouse Model, Pillar Of Type 1 Diabetes Research, Jeremy T. Richardson, Heidi M. Batdorf, Thomas M. Martin, Susan J. Burke, David H. Burk, J. Jason Collier
The Icr Mouse: An Mhc Matched Control For The Non-Obese Diabetic Mouse Model, Pillar Of Type 1 Diabetes Research, Jeremy T. Richardson, Heidi M. Batdorf, Thomas M. Martin, Susan J. Burke, David H. Burk, J. Jason Collier
Medical Student Research Poster Symposium
Type 1 diabetes (T1D) affects approximately 9 million individuals and accounts for 5-10% of diabetes worldwide. Furthermore, the global incidence of T1D has in recent years starkly increased and is generally attributed to an exacerbated interplay between polygenic and environmental risk factors. The precise etiology of the disease is to this day unknown; However, a growing body of evidence suggests that viruses and other environmental stressors may disrupt an already fragile pancreatic milieu, trigger autoimmune events, and impede restoration to a homeostatic state once the challenge removed. Still, much of the mechanisms leading to abnormal immune cell infiltration of the …
Racial Disparity In Glycemic Outcome During Real World Use Of An Advanced Hybrid Closed Loop System (Ahcl) Among Youth With Type 1 Diabetes (T1d), Nicholas Christakis, Marcella Gioe, Stuart Chalew
Racial Disparity In Glycemic Outcome During Real World Use Of An Advanced Hybrid Closed Loop System (Ahcl) Among Youth With Type 1 Diabetes (T1d), Nicholas Christakis, Marcella Gioe, Stuart Chalew
Medical Student Research Poster Symposium
Introduction. African-American (B) youth with Type 1 Diabetes consistently have higher A1c than White (W) patients, even when using open-loop insulin pumps. AHCL technology utilizes glucose sensor data to guide automatic adjustments of insulin by the pump throughout the day to mitigate hyper and hypoglycemia. Potentially AHCL could reduce or eliminate disparity in glycemic outcome in high-risk patient populations Methods and Results. We performed a retrospective chart review of clinic patients who were using Tandem Control IQ (CIQ) AHCL system. Patients were trained in AHCL use by the manufacturer’s representative and then followed routinely in diabetes clinic at the Children’s …