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Full-Text Articles in Medicine and Health Sciences
Identification Of Biomarkers Associated With Rous Sarcoma Virus-Induced Tumors In Two Divergently Selected Chicken Lines, Ashley Hayden
Identification Of Biomarkers Associated With Rous Sarcoma Virus-Induced Tumors In Two Divergently Selected Chicken Lines, Ashley Hayden
Graduate Theses and Dissertations
Poultry has become especially important to genetic research due to breeding feasibility, short generation turnover, and ease of maintaining large populations. The discovery of virus induced cancer has paved the way for further genetic studies. Rous Sarcoma Virus (RSV) is a tumor-causing virus that infects poultry. While not prevalent today, it can serve as a model for virus-induced cancer in humans and create additional insight to marker assisted selection in poultry. Genetically selected Arkansas Progressor (AP) and Arkansas Regressor (AR) chicken lines have been established and maintained at the Arkansas Experimental Station (AES) in Fayetteville, AR. Previous research has investigated …
Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson
Effect Of Passive Heating On Males And Females With Elevated Arterial Stiffness, Forrest Blake Robinson
Graduate Theses and Dissertations
Context: Cardiovascular disease (CVD) is one of the leading causes of mortality in the United States, accounting for about 1 in every 4 deaths annually. Studies have shown that passive heating does have some degree of effect on arterial stiffness, but not much is known about populations with higher stiffness. Objective: To examine the independent effect of core temperature increase during passive heating on arterial stiffness. Methods: Participants visited the lab three times; one familiarization and two experimental trials. The experimental trials consisted of subjects being passively heated in an environment of 40°C / 40% relative humidity (HEAT) or normal …
A Descriptive Case Study Of Individuals With Presumed Ocular Histoplasmosis Syndrome Utilizing A Facebook Support Group, Lisa Aimee Thompson
A Descriptive Case Study Of Individuals With Presumed Ocular Histoplasmosis Syndrome Utilizing A Facebook Support Group, Lisa Aimee Thompson
Graduate Theses and Dissertations
This dissertation describes the experiences of people diagnosed with presumed ocular histoplasmosis syndrome as they participate in an online peer-support group on Facebook. This is a descriptive case study of factors related to adjustment, treatment, emotional distress, access to services, and online peer support. Participants were interviewed and observed, and documents were collected to describe this phenomenon.
In Vitro Analysis Of Short Chain Fatty Acids And Human Fecal Microbiota Stimulated By Pectin Sources, Byungjick Min
In Vitro Analysis Of Short Chain Fatty Acids And Human Fecal Microbiota Stimulated By Pectin Sources, Byungjick Min
Graduate Theses and Dissertations
As interest increases for colonic health, various studies have been conducted to investigate functional ingredients for host health and prevention of chronic disease in humans such as colon cancer and Type 2 diabetes. In particular dietary fiber has been reported to have beneficial effects on colonic health. More recently, dietary fiber has been categorized based on its characteristics and numerous studies have been conducted to determine correlations with chronic diseases. Pectin is a naturally occurring biopolymer that has been used in various applications for purposes of pharmaceutical and biotechnology. Pectin is a soluble dietary fiber and can be entirely fermented …
Characterization Of Host Immune Responses To Eimeria Adenoeides Infection In Turkey Poults, Ujvala Deepthi Gadde
Characterization Of Host Immune Responses To Eimeria Adenoeides Infection In Turkey Poults, Ujvala Deepthi Gadde
Graduate Theses and Dissertations
Coccidiosis is a common enteric disease of turkeys that is caused by protozoan parasites belonging to the genus Eimeria. There are about seven species of Eimeria that affect turkeys and of these E. adenoeides is the most pathogenic and commonly recognized. Infection with Eimeria is known to induce a long lasting protective immunity in chickens, but nothing is known regarding the acquisition of immunity to Eimeria in turkeys. The experiments reported here were aimed at investigating the biological and cellular immune response to E. adenoeides in turkey poults under different conditions of exposure. In experiment 1 (Chapter II), 20 …
Proteomic Studies Of The Influenza Virus-Human Cell Interactions: The Responses Of Host Cell Protein Expression To Viral Infection And The Novel Host Proteins That Interact With Virus Protein Ns1, Yimeng Wang
Graduate Theses and Dissertations
Influenza A viruses (IAVs) continue to be a threat to human health. Despite extensive studies, the mechanisms underlying the IAVs-host interactions during IAV infection remain elusive. We employed quantitative proteomic methods to systematically explore the host cell protein expression responses to IAV infection and examine the function of a critical IAV protein called NS1 by identifying its host binding partners. Specifically, we used a 2-dimentional gel electrophoresis (2-DE) based proteomic method to screen host proteins whose expression was substantially altered by IAV. One critical protein named IκB kinase-gamma (IKKγ) was found to be significantly down-regulated during IAV infection. Functional studies …
Efficacy Of Selected Disinfectants Against Salmonella Isolates From Broiler Breeders, Arslan Aslam
Efficacy Of Selected Disinfectants Against Salmonella Isolates From Broiler Breeders, Arslan Aslam
Graduate Theses and Dissertations
Salmonella have been causing huge losses in the poultry industry and have been a major cause food borne illness for many years. Salmonella infections in humans from poultry have been increasing. Good hygiene and biosecurity measures can reduce the incidence of Salmonella infections at poultry farms. Disinfection is a most important measure taken to prevent Salmonellosis in poultry. This research was conducted to determine the efficacy of 12 disinfectants against seven Salmonella isolates in the presence and absence of organic matter. A bacterial solution of a specific optical density value was prepared and .05x, .1x and .2x concentrations of disinfectants …
Investigation Of A Locus On Chromosome 9 For Contributions To Pulmonary Hypertension Syndrome In Broilers, Sriram Krishnamoorthy
Investigation Of A Locus On Chromosome 9 For Contributions To Pulmonary Hypertension Syndrome In Broilers, Sriram Krishnamoorthy
Graduate Theses and Dissertations
Although the ascites syndrome in chickens has been investigated for years, it continues to inflict financial losses to the world poultry industry. It is estimated that 8% of the 361 million broiler deaths are due to ascites leading to losses of millions of dollars annually. Efforts to curb the incidence of ascites are typically designed to slow early growth. This limits the birds' ability to show its true genetic potential and impacts later yields. In 1994 lines divergent for susceptibility to ascites were established from a commercial sire line through sibling selection of birds reared at local altitude after testing …
A Role Of Environmental Components In Autoimmune Vitiligo Of Smyth Line Chickens, Lei Dong
A Role Of Environmental Components In Autoimmune Vitiligo Of Smyth Line Chickens, Lei Dong
Graduate Theses and Dissertations
The Smyth line (SL) of chickens is a well-established animal model for the study of spontaneous autoimmune vitiligo, displaying all the characteristics of human vitiligo. In humans, phenolic derivative 4-tertiary butyl phenol (4-TBP) has been shown to trigger vitiligo in susceptible individuals. In vitiligo-prone SL-chickens, live turkey herpesvirus (HVT) infection at hatch was identified as the most effective trigger of SL-vitiligo expression. This dissertation examined the role of the environmental factors 4-TBP and HVT in the etiology of SL-vitiligo. Specifically, the generation of reactive-oxygen-species by melanocyte-containing feather tissue (MC-FT) and cultured melanocytes in response to 4-TBP exposure in vitro (Study …
Interactions Of Nitric Oxide And Superoxide Pathways In Hyperglycemic Endothelial Cells, Steven Clay Rogers
Interactions Of Nitric Oxide And Superoxide Pathways In Hyperglycemic Endothelial Cells, Steven Clay Rogers
Graduate Theses and Dissertations
Cardiovascular complications arising from diabetic hyperglycemia represents one of the leading causes of death and greatest public health challenges of modern societies. Despite state-of-the-art glucose control, diabetic patients remain at a markedly increased risk of cardiovascular disease. The loss of endothelial function (the development of diabetic endothelial dysfunction) has been implicated in the development of numerous diabetic cardiovascular diseases. The endothelial cell produces many vasoactive substances, hormones and cytoprotective biological factors. Endothelial cells are also involved in and affected by the initiation of inflammatory responses through the release and interaction of cytokines and other immune system molecules. Therefore, regulation of …
Can Antioxidant-Rich Berries Improve Risk Factors Associated With Cardiovascular Disease In Postmenopausal Smokers?, Jordan Alaine Teeple
Can Antioxidant-Rich Berries Improve Risk Factors Associated With Cardiovascular Disease In Postmenopausal Smokers?, Jordan Alaine Teeple
Graduate Theses and Dissertations
The purpose of this study was to examine the effects of smoking on risk factors associated with cardiovascular disease (CVD) and determine the efficacy of antioxidant-rich berries in ameliorating these risk factors in postmenopausal smokers. Menopause and cigarette smoking have been identified as major risk factors for CVD due to a decrease in antioxidant protection, increase in inflammation and oxidative stress, and adverse changes in serum lipids. Antioxidants, specifically flavonoid compounds found in blackberries and blueberries, have been shown to prevent low-density lipoprotein cholesterol oxidation and thus prevent downstream inflammation and oxidative stress. Healthy, postmenopausal nonsmokers (n=14) and smokers (n=31) …
Evaluation Of The Pilot Program, Pediatric Early Warning Sentinel Surveillance Program (Pewss), And Its Efficacy In Monitoring Pediatric Illness In Clark County, Nevada, Michelle Lee Lutman
Evaluation Of The Pilot Program, Pediatric Early Warning Sentinel Surveillance Program (Pewss), And Its Efficacy In Monitoring Pediatric Illness In Clark County, Nevada, Michelle Lee Lutman
UNLV Theses, Dissertations, Professional Papers, and Capstones
The influenza outbreak that occurred during 2009 stimulated the formation of several surveillance programs throughout the country. The majority monitor only influenza; however, there are several other circulating respiratory pathogens, especially within the pediatric community. These other respiratory pathogens cause a variety of illnesses, such as bronchitis, pneumonia, croup, etc. Prior research has provided the medical community with valuable information about respiratory illnesses, especially those which afflict pediatric patients. Areas of knowledge including seasonality, demographics, signs and symptoms, prevention measures, and pathogenicity, have been greatly expanded over the years. This information has been of tremendous help to the medical community …
Methodological Quality Of Quantitative Nursing Lesbian, Gay, Bisexual, And Transgender Research From 2000 To 2010, Michael Johnson
Methodological Quality Of Quantitative Nursing Lesbian, Gay, Bisexual, And Transgender Research From 2000 To 2010, Michael Johnson
UNLV Theses, Dissertations, Professional Papers, and Capstones
Lesbian, gay, bisexual, and transgender (LGBT) people constitute one of the largest underserved populations in any nursing setting. Despite the large LGBT populations, very little nursing research has been conducted on these populations. Nurse researchers have recommended that nursing researchers end the silence on LGBT research. To accomplish this, the methodological rigor of LGBT nursing research must be evaluated and improved upon. Currently, no literature examines the methodological quality of quantitative nursing LGBT research. Using a cross-sectional design, it was the purpose of this study to evaluate the methodological quality of quantitative nursing LGBT research from 2000 to 2010 using …
The Relationship Between Health Attitudes, Beliefs, Health Locus Of Control And Use Of Breast Cancer Screening Modalities In Elderly Hispanic Women, Debra Kay Gillett, Rosamaria Ortiz
The Relationship Between Health Attitudes, Beliefs, Health Locus Of Control And Use Of Breast Cancer Screening Modalities In Elderly Hispanic Women, Debra Kay Gillett, Rosamaria Ortiz
Theses and Dissertations - UTB/UTPA
A non-experimental design was used to examine the relationship between health attitudes, beliefs, locus of control and the use of breast cancer screening modalities in elderly Hispanic women in this pilot study. Leininger's Theory of Culture Care Diversity and Universality and the Health Belief Model were the supporting theoretical frameworks. Research was conducted at the Amigos del Valle senior centers in Hidalgo County and included 52 English-speaking elderly Hispanic volunteer participants. Instruments used for data collection were the Health Care Attitudes and Beliefs Scale and the Multidimensional Health Locus of Control Scale. Results of this study revealed that there appears …
A Comparison Of The Effects Of Moderate- And High-Carbohydrate Diets On Coronary Heart Disease Risk Factors: A Pilot Study, Margaret Helen Fernandez, Julia Ava Niehaus Soper
A Comparison Of The Effects Of Moderate- And High-Carbohydrate Diets On Coronary Heart Disease Risk Factors: A Pilot Study, Margaret Helen Fernandez, Julia Ava Niehaus Soper
Theses and Dissertations - UTB/UTPA
This pilot study compared the effects of two diets on total cholesterol to high- density lipoprotein cholesterol ratio, body mass index, and waist circumference. A diet of 15% protein, 55% or more carbohydrate, and 30% or less fat was compared to a diet of 30% protein, 40% carbohydrate, and 30% fat. Lipid levels and anthropometric measurements were obtained on 18 adult males with moderately elevated lipid levels before and after 12 weeks of dietary intervention. Analyses showed variances between and within the study groups in the areas of anthropometric measurements and lipid levels; no statistically significant differences between the groups …