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Full-Text Articles in Medicine and Health Sciences

Vampires And Other Diseases: Stochastic Infection Dynamics Of Small Populations, Marijn Jaarsma Apr 2022

Vampires And Other Diseases: Stochastic Infection Dynamics Of Small Populations, Marijn Jaarsma

Honors Projects in Science and Technology

Mathematical models are powerful tools often applied in the field of epidemiology. The type and shape of the model will differ between different types of diseases. In this study, stochastic dynamical models are applied to the entertaining example of vampires, and the results of this analysis are compared to real-life diseases with small populations of infected. The data used comes from pop-culture depictions of vampires in literature, television shows, movies, and fan pages associated with these depictions. The aim of this study is to serve as an educational tool for modeling diseases with small populations to predict and control the …


The Hiv Epidemic In Dominican Republic: Local Issues With A Global Effect, Brianna Sutherland Apr 2019

The Hiv Epidemic In Dominican Republic: Local Issues With A Global Effect, Brianna Sutherland

Honors Projects in Science and Technology

The island of Hispaniola, consisting of the vastly different nations of Haiti and Dominican Republic, creates an interesting dichotomy to study, especially because they rank amongst the top fifty highest seroprevalence rates for human immunodeficiency virus (HIV) globally. To date, little has been done to analyze the contributing factors that lead to the observed high rates of HIV in the population because most literature has focused on Sub-Saharan Africa. Therefore, the goal of this project was to review literature and global data in order to explore the unique factors contributing to the HIV epidemic in the Dominican Republic. Key communities …


Predicting The Effects Of Medicaid's Sobriety Requirements On The Spread Of Hepatitis C In Rhode Island, Mary Cate Gallagher Apr 2019

Predicting The Effects Of Medicaid's Sobriety Requirements On The Spread Of Hepatitis C In Rhode Island, Mary Cate Gallagher

Honors Projects in Science and Technology

Hepatitis C (HCV) is the most prevalent infectious disease in America (1). This virus is spread through blood to blood contact, and disproportionally affects the People Who Inject Drugs (PWID) community. There is a 99% effective curative treatment available. However, Rhode Island Medicaid stipulates that a patient must be six months sober before accessing this treatment. Because of this barrier, less than 16% of people infected with HCV are able to access the curative treatment and the disease continues to run rampant throughout the state. Using SIS disease spread modeling techniques fit to current published Rhode Island Department of Health …


Time Of Year Affects Surgical Outcome Of Pediatric Congenital Heart Disease, Krystin Sinclair Apr 2016

Time Of Year Affects Surgical Outcome Of Pediatric Congenital Heart Disease, Krystin Sinclair

Honors Projects in Science and Technology

Approximately 35,000 children are born in the US each year with Congenital Heart Disease (CHD). Surgical timing for many of these conditions is elective, and the distribution of surgical cases, therefore, varies with time of year. The hypothesis of this project is that time of the year for surgery is associated with mortality, length of hospital stay (LOS), and total hospital costs. A retrospective, cohort study was performed, using the Pediatric Health Information Systems (PHIS) Database to investigate these relationships.


An In-Depth Look At Recent Influenza Seasons And Vaccine Effectiveness, Ariana Ricci Apr 2013

An In-Depth Look At Recent Influenza Seasons And Vaccine Effectiveness, Ariana Ricci

Honors Projects in Science and Technology

This paper aims to present an in-depth exploration of immunology, the influenza virus, vaccination, and vaccination’s effectiveness with respect to influenza. It also delves into the possible causes behind the large increase in early childhood deaths during the 2003-2004 influenza season, which was a turning point in terms of influenza incident reporting. Finally, data analysis on the relationship between childhood flu vaccine coverage and childhood outpatient ILI (influenza-like illness) visits by region is presented as a measurement of vaccine effectiveness and identifier of trends. Although this relationship was not statistically significant (alpha=0.05) regionally, this simply points to alternate factors that …


Effects Of Clostridium Difficile On The Human Immune Response, Mike Mcgovern Apr 2013

Effects Of Clostridium Difficile On The Human Immune Response, Mike Mcgovern

Honors Projects in Science and Technology

Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics. By studying the way in which the pathogen interacts with the human immune system, it is possible to better understand how the body naturally fights off the disease. This knowledge can allow medical professionals to develop treatments that can help curtail the infection before serious symptoms occur. Working under a grant program alongside Professors Kirsten Hokeness and Chris Reid, I was able to research the effects that exposure to the C. …