Medicine and Health Sciences Commons^™

Antibiotics And The Wasting Disease In Neonatally Thymectomized Rats, Douglas M. Grignon

Loma Linda University Electronic Theses, Dissertations & Projects

The administration of the antibiotic, Chloramphenicol, to pregnant rats just prior to, and for four days after delivery, diminishes the incidence of the so-called "Wasting Disease" in neonatally thymectomized rats.

A total of 50 rats were divided into the following groups:

1. Thymectomy only---nonmedicated 17 rats
2. Thymectomy only---medicated 12 rats
3. Thymectomy-adrenalectomy---nonmedicated 5 rats
4. Thymectomy-adrenalectomy---medicated 8 rats
5. Controls---nonmedicated 4 rats
6. Controls---medicated 4 rats

Chloramphenicol was administered in the drinking water to the mothers of groups 2, 4 and 6 for about 2 days prior to delivery and 4 days after. On the day of birth or within three days after birth, the …

The Effect Of Varying Protein Intake On Trichinella Spiralis Infection In Mice, Clare K. Kwan

Loma Linda University Electronic Theses, Dissertations & Projects

Three hundred Swiss Webster albino mice three weeks of age were placed on low (8%), medium (24%), high (48%) protein levels and a commercial laboratory animal feed, Purina Chow for various lengths of time: (1) simultaneously with infection, and four weeks thereafter, (2) three weeks before infection and throughout the four-week infection period, and (3) six weeks prior to infection and during the infection period. The protein source was casein. Sixty of the 300 mice used served as noninfected controls, and the other 240 were each infected with 400 washed, suspended Trichinella spiralis larvae obtained from a rat by the …

A Study Of The Effect Of Varying Serum Phenylalanine Levels On Changes In Intelligence Quotient, Darlene Imai Manullang

Loma Linda University Electronic Theses, Dissertations & Projects

Data from thirty medical records of phenylketonuric children under treatment were investigated to determine at which serum phenylalanine level (0-3.9 mg. %, 4-7.9 mg %, 8-11.9 mg. %, greater than 12 mg. %) there would be the greatest increase in intelligence. The children involved in the study were divided into the following groups according to the age dietary treatment was initiated: 0 through 5 months, 6 through 11 months, 12 through 23 months, and over 2 years of age.

Among 6 patients who were placed on the diet during the first 5 months of life, it appears that the optimal …

Effect Of 9 Α-Fluorohydrocortisone Acetate On Gastric And Salivary Electrolytes Of Normal Fasting Subjects, Ardis Stern Beckner

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of 9α-FF on the Na:K ratio, chloride, and pH of saliva and gastric secretions, and on the total and free acid of gastric juice in normal human subjects was investigated. This study was designed to investigate whether conditions could be produced in the normal human subject similar to those present in patients with primary aldosteronism by using large doses of 9α-FF. August and others found a change in salivary electrolytes when cortisone, desoxycortisone, or ACTH were given to normal subjects. In these cases as in primary aldosteronism there was a decreased Na:K ratio and potassium excretion, with sodium …

A Review Of Drug Addiction And A Study Of Its Relation To Carbohydrate Metabolism, Eppie Chung Hartsuiker

Loma Linda University Electronic Theses, Dissertations & Projects

The specter of addiction eventually involves everyone of the community. It is a three-fold problem of socio-economic, psychological, and physiological factors. The least understood is the physiological or biochemical aspect of addiction.

It has been postulated that an upset in carbohydrate metabolism may be a biochemical cause of addiction. Several avenues were employed to investigate this possible cause of addiction.

1. A diet survey was conducted and revealed a greater consumption of refined carbohydrates, confections and alcoholic beverages in addicts.

2. Five-hour oral glucose tolerance tests were performed on 7 addicts and 12 non-addicts. These tests revealed that there were decreased glucose …

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Some Supplementary Studies With Wheat Proteins, Gerald G. Porter

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

Introduction The importance of selecting only foods containing proteins of high nutritive value has been somewhat over-emphasized in the past because of the failure to recognize the possibility of supplementary relationships among proteins that are not of high quality. Hart (11) has wisely suggested that a food should not be relegated to an inferior class because its proteins, when fed alone, are not of high biological value. Sherman (31) has reminded us that with a knowledge of the nutritional chemistry of the proteins of various foods, it becomes relatively easy to utilize their supplementary relationships so that …

Intravenous Procaine During Thoracic Surgery, Forrest E. Leffingwell

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

Surgery on the heart and paracardial structures or traction on the hilus of the lung may initiate serious arrhythmias which can result in death if not promptly controlled. Procedures involving the pericardium are particularly apt to be followed by severe derangements of rhythm. Thus anesthesiology is faced with another challenge.

It is now evident that the intravenous administration of procaine has become a valuable addition to the armamentarium of the anesthesiologist in his endeavor to preserve the integrity of the thread of life while the surgeon carries out his heroic assignment without restrictions.

The Central Action Of Procaine, Clarence W. Olsen

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

Procaine was introduced as a local anesthetic with advantage over cocaine, especially as regards relative freedom from dangerous central effects. It [now] appears that when procaine hydrochloride is injected intravenously, the indications of a central effect are more emphatic when the solution is given rather rapidly.

Probably some of the central effects of procaine can be obtained with local infiltration. This is, of course, generally admitted when untoward results occur, but it should also be considered in connection with the favorable effects. Macpherson recently expressed the idea that in some cases we are getting the beneficial effects of procaine injection …

A Resume Of Intravenous Procaine Therapy, Fred B. Moor

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

Summary:

1. The intravenous injection of procaine hydrochloride for a variety of clinical conditions constitutes a surprising new chapter in therapeutics.

2. With adequate precautions as to dosage and rate of administration, procaine can be safely given by the intravenous route in concentrations of 0.1 to 1 per cent.

It has been used successfully for serum sickness, the pruritis of jaundice, trauma of soft tissues, bones and joints, in the prevention and treatment of cardiac arrhythmias during intrathoracic surgery, for the relief of pain in osteoarthritis, for the control of pain during the dressing of burns, for postoperative pain, and …

The Circulatory Effects Of Histamine, Fred B. Moor

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

No abstract provided.

Cerebral Anoxia And Its Residuals: I. Historical Introduction, Cyril B. Courville

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

No abstract provided.