Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- Virginia Commonwealth University (20)
- Children's Mercy Kansas City (15)
- University of North Dakota (9)
- Cleveland State University (6)
- HCA Healthcare (5)
-
- Chapman University (4)
- University of Vermont (3)
- Thomas Jefferson University (2)
- University of Alabama in Huntsville (2)
- University of Nevada, Las Vegas (2)
- University of Southern Maine (2)
- CentraCare Health (1)
- Department of Primary Industries and Regional Development, Western Australia (1)
- Dominican University of California (1)
- Georgia Southern University (1)
- Himmelfarb Health Sciences Library, The George Washington University (1)
- Kutztown University (1)
- Misericordia University (1)
- Old Dominion University (1)
- Pittsburg State University (1)
- Portland State University (1)
- University of Louisville (1)
- University of New England (1)
- University of South Alabama (1)
- University of Texas at Tyler (1)
- Keyword
-
- Children (6)
- Biology (3)
- Depression (3)
- Teenagers (3)
- Vermont (3)
-
- AUD (2)
- Alcohol (2)
- Anxiety (2)
- Chemistry (2)
- Chemotherapeutics (2)
- ER (2)
- Ethanol (2)
- Forensic Science (2)
- PK/PD (2)
- Pharmacodynamics (2)
- Pharmacokinetics (2)
- Psychology (2)
- ADHD (1)
- AKI (1)
- AML (1)
- AMPK (1)
- ATP (1)
- Acetaldehyde (1)
- Acetyl indole (1)
- Acute Myeloid Leukemia (1)
- Acute hyperkalemia (1)
- Acute hyperkalemia managementZS-9 (1)
- Addiction Treatment (1)
- Adverse effects; cannabinoid addiction; cannabinoids; chronic pain; efficacy; medical marijuana; pain management (1)
- Aerosol (1)
- Publication Year
- Publication
-
- Undergraduate Research Posters (17)
- Posters (13)
- Physician Assistant Scholarly Project Posters (9)
- Undergraduate Research Posters 2012 (4)
- Family Medicine Clerkship Student Projects (3)
-
- Pharmacy Faculty Books and Book Chapters (3)
- Central & West Texas Research Day 2024 (2)
- Continental, MidAmerica, & Mountain Divisions Research Day 2024 (2)
- Finding Aids (2)
- Graduate Research Posters (2)
- Maine Collection (2)
- Master of Science in Physician Assistant Studies Capstone Presentations (Center City) (2)
- Summer Community of Scholars Posters (RCEU and HCR Combined Programs) (2)
- Undergraduate Research Symposium Posters (2)
- Bulletins 4000 - (1)
- College of Sciences Posters (1)
- Dental Hygiene Student Scholarship (1)
- Faculty Posters (1)
- Neuroscience Student Research Posters (1)
- Nurse Presentations (1)
- Nursing | Student Research Posters (1)
- Pharmacy Faculty Data Sets (1)
- Pharmacy Posters (1)
- Population Reports (1)
- Poster Presentations (1)
- Presentations (1)
- Sikaiana Ethnography (1)
- Student Research Poster Presentations 2020 (1)
- Systems Science Friday Noon Seminar Series (1)
- Undergraduate Arts and Research Showcase (1)
Articles 1 - 30 of 84
Full-Text Articles in Medicine and Health Sciences
Sdrnas Participate In The Maintenance And Onset Of Prostate Cancer, Neil Chaudhary
Sdrnas Participate In The Maintenance And Onset Of Prostate Cancer, Neil Chaudhary
Poster Presentations
What is an sdRNA? Noncoding RNA (ncRNA) is a class of RNA that includes microRNA (miRNA) and small nucleolar RNA (snoRNA). Fragments excised from ncRNAs are known as noncodingderived RNA (ndRNA). A certain class of ndRNAs that are derived from snoRNAs have been denoted as Small Nucleolar Derived RNAs (sdRNAs). Our lab has previously hypothesized and demonstrated that sdRNAs display regulatory functions on target genes, similar to the functions of miRNAs. sdRNAs are almost identical to microRNAs and differ mainly in their source of origin.
Our lab has shown that sdRNA-93 is frequently misexpressed in breast cancer cell lines and …
A Retrospective Study Of Procalcitonin Utilization In Clinical Practice, Tanner Norris, Matthew Yurkewicz, Patrick Jenkins, Beth Hicks, Dmitriy Scherbak
A Retrospective Study Of Procalcitonin Utilization In Clinical Practice, Tanner Norris, Matthew Yurkewicz, Patrick Jenkins, Beth Hicks, Dmitriy Scherbak
Continental, MidAmerica, & Mountain Divisions Research Day 2024
No abstract provided.
Pharmacoepidemiology Of Glp-1 Receptor Agonists, Nicholas E. Woessner
Pharmacoepidemiology Of Glp-1 Receptor Agonists, Nicholas E. Woessner
Continental, MidAmerica, & Mountain Divisions Research Day 2024
No abstract provided.
Pantoprazole Induced Pancytopenia In A Post-Chemotherapy Patient: A Case Report, Rohan Divecha, Caleb Nieves, Paul Mathew
Pantoprazole Induced Pancytopenia In A Post-Chemotherapy Patient: A Case Report, Rohan Divecha, Caleb Nieves, Paul Mathew
Central & West Texas Research Day 2024
No abstract provided.
Cortisol In Elderly Trauma Patients, Sophia Jimenez, Ernest Gonzalez, Leslee Keilty, Carol Wang
Cortisol In Elderly Trauma Patients, Sophia Jimenez, Ernest Gonzalez, Leslee Keilty, Carol Wang
Central & West Texas Research Day 2024
No abstract provided.
Reminiscence Therapy For Prevention Of Post-Stroke Anxiety And Depression In Adults, Carly Porter
Reminiscence Therapy For Prevention Of Post-Stroke Anxiety And Depression In Adults, Carly Porter
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Introduction
Anxiety and depression are prevalent after a stroke.1,2 Peer support is a non-pharmacologic intervention utilized to manage post-stroke anxiety and depression with inconsistent results.3 Reminiscence therapy is an intervention that has been studied in the dementia population but is a relatively new intervention for the stroke population and has the potential to impact the psychological care provided to stroke patients.4
Stimulant Medication Use In Children/Adolescent Athletes With Adhd Reduce The Recovery Time Of Concussions And Traumatic Brain Injury, Matthew Lee
Master of Science in Physician Assistant Studies Capstone Presentations (Center City)
Introduction
- Concussions and TBIs are well-known injuries occurring 30-50 million times a year worldwide and are commonly seen in sports.1 The majority of TBIs are mild yet still have the potential to cause lifelong detrimental effects.
- Short- and long-term complications include difficulty thinking, difficulty concentrating, changes in emotions and personality, decreased memory and sensation, and may lead to depression and dementia.2
- Especially in children and adolescents who are undergoing brain development.
- There are no known prophylactic medications, however, some studies have indicated that sympathomimetic drugs, MPH, may be neuroprotective in the setting of TBIs.
- The purpose of this …
The Role Of The Nlrp3 Inflammasome In Alzheimer's Disease, Ethan S. Terman
The Role Of The Nlrp3 Inflammasome In Alzheimer's Disease, Ethan S. Terman
Undergraduate Research Posters
This study examines the consequences of Alzheimer’s in rat and mice test subjects. The goal is to identify the effects of certain NLRP3 inhibiting drugs and to see if there are any noticeable effects in regards to impeding the pathological development of Alzheimer’s disease. The results are visualized by implementing the immunohistochemical process to identify neurodegeneration in the brain and to assess the expression levels of amyloid beta as an indicator of Alzheimer’s pathology. Other tests are also conducted on these transgenic mice to gauge cognitive functioning levels during the onset of their disease, those being behavior tests, but not …
Video Game Therapy For Adhd Managment, Wilhelm Alec Sison Beroncal
Video Game Therapy For Adhd Managment, Wilhelm Alec Sison Beroncal
Nursing | Student Research Posters
Attention Deficit Hyperactivity Disorder (ADHD) stands out as the most common childhood neurodevelopmental disorder, leading to functional challenges in various aspects of the daily lives of affected young individuals (Bul et al., 2016).
There is no current cure for ADHD, however effective treatments are available through medications. The FDA has authorized two types of medications for managing ADHD in children as young as 6 years old: stimulants, such as methylphenidate and amphetamine (e.g. Adderall), and non-stimulant options including Strattera, Intuniv, Kapvay, and Qelbree (U.S. Food and Drug Administration, 2023).
The choice of treatment is highly individualized to meet the specific …
Isoprenylation Inhibition Suppresses Fcεri-Mediated Mast Cell Function And Allergic Inflammation, Aditya Kotha, Jordan M. Dailey, Aslamuzzaman Kazi, Said Sebti, John J. Ryan
Isoprenylation Inhibition Suppresses Fcεri-Mediated Mast Cell Function And Allergic Inflammation, Aditya Kotha, Jordan M. Dailey, Aslamuzzaman Kazi, Said Sebti, John J. Ryan
Undergraduate Research Posters
Allergic disease is driven by cell signaling cascades that activate immune cells. One key player is mast cells, which is activated by IgE antibodies signaling through the high affinity IgE receptor, FceRI. Therefore, targeting FceRI-mediated cascades can offer for novel treatments for allergic disease. Statins have been demonstrated to reduce the severity of asthma, a common allergic airway disease. Statins are an FDA approved class of drugs with the intended purpose of lowering blood cholesterol. We previously found that while statins inhibit mast cell function in allergic disease, these anti-inflammatory effects vary widely amongst differing mouse strains and human donors, …
Proposing An Rna Interference (Rnai)-Based Treatment For Human Immunodeficiency Virus (Hiv) By Analyzing The Post-Transcriptional Gene Targeting Of Sars-Cov-2, Hepatitis C Virus, And A549 Lung Cancer Cells, Arjun Jagdeesh
Undergraduate Research Posters
Human Immunodeficiency Virus (HIV) is a retrovirus that infects CD4+ T cell lymphocytes in humans, leading to the development of Acquired Immunodeficiency Syndrome (AIDS) if left untreated. While current treatment methods, including antiretroviral combination treatments, effectively limit HIV replication, HIV can evade these treatments due to its high mutation rate. Long-term antiretroviral treatment can also be toxic to patients, meaning patients would benefit from a new mechanism of HIV treatment. RNA interference (RNAi) is an antiviral pathway found in mammals, plants, and insects that involves a small-interfering RNA that is incorporated into a protein complex called the RNA-induced Silencing Complex …
Over-The-Counter Approval Of Progestin-Only Pills, Hannah Grace Donovan
Over-The-Counter Approval Of Progestin-Only Pills, Hannah Grace Donovan
Family Medicine Clerkship Student Projects
Most women in the United States use contraception at some point in their life. While there are many types of short- and long-acting reversible birth control options available via prescription, the oral contraceptive pill (OCP) remains the most used reversible contraceptive agent. The proportion of those using an OCP is inversely proportional with age; more specifically, people who can get pregnant between the ages of 15 and 29 use OCPs most frequently. However, people in this age range may face increased barriers to obtaining contraception, such as cost, insurance, social and familial factors, policy, transportation, and access to healthcare. In …
Testing The Efficacy And Synergistic Components Of Sesamol And Black Rice Extract On Human Colon Cancer Cells, Sera Lim, Philip M. Gerk
Testing The Efficacy And Synergistic Components Of Sesamol And Black Rice Extract On Human Colon Cancer Cells, Sera Lim, Philip M. Gerk
Undergraduate Research Posters
Purpose: Systemic treatment of colorectal cancer involves chemotherapeutic agents which elicit serious and negative side effects from the toxicity of the drug. To address this issue, we are testing dietary supplements for their efficacy against human colon cancer cell lines and also their potential synergistic effects when combined with conventional chemotherapy. Dietary supplements (specifically sesamol and black rice extract) exhibit anticancer, anti-inflammatory, and chemo-preventive properties. Meanwhile, one of the cancer resistance mechanisms is the upregulation of drug elimination mechanisms, leading to multi-drug resistance. We hypothesize that dietary compounds will act as chemo-enhancers, thus enhancing potency of the chemotherapy drug(s) on …
Groundwater Remediation Using Modified Biochar, Kers Ung-Watson, Ismail Abdulraheem, Nikki Tibayan, Suraj Pochampally
Groundwater Remediation Using Modified Biochar, Kers Ung-Watson, Ismail Abdulraheem, Nikki Tibayan, Suraj Pochampally
Undergraduate Research Symposium Posters
Biochar, a lightweight black residue made of carbon, has proved to be an effective adsorbent to remove TCE from groundwater. Not only is it an economical substitute for conventional adsorbents but it can be created by using a variety of organic materials. For this project, it will rely on walnut shell feedstock to create biochar as this had the best ability to adsorb TCE.
Identification Of Lipid Species: Potential Biomarkers For Early Detection Of Hepatocellular Carcinoma, Kit Yee Leung, Kaylee Freitas
Identification Of Lipid Species: Potential Biomarkers For Early Detection Of Hepatocellular Carcinoma, Kit Yee Leung, Kaylee Freitas
Undergraduate Research Symposium Posters
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is associated with cirrhosis. Poor survival rate of HCC is due to diagnosis of HCC at late stage.
Hydroxyapatite Toothpaste On Caries Prevention In Children, Samantha Richardson, Kelly Vaughan
Hydroxyapatite Toothpaste On Caries Prevention In Children, Samantha Richardson, Kelly Vaughan
Dental Hygiene Student Scholarship
Are Hydroxyapatite Toothpastes The Answer To Fluoride Free Patients?
Richardson, Samantha 1 and Vaughan, Kelly 2
Dental Hygiene Program, Virginia Commonwealth University
Abstract:
Objectives/Aims: With the rising trend to become more clean with our ingredient lists, we are facing more patients refusing fluoride treatments and fluoridated toothpastes. This trend has been prevalent in our younger generations due to parents only wanting the purest natural ingredients for their children and now declining fluoride application. The goal of this literature is to find a safe alternative toothpaste that will be just as effective as fluoride.
Methods: This review of literature has been …
Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles
Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles
Graduate Research Posters
Background: We have shown modulations in glycogen synthase kinase 3 beta (GSK3B) abundance or activity regulate ethanol consumption, suggesting potential as a therapeutic target for alcohol use disorder (AUD). Here we report the GSK3B inhibitor tideglusib’s actions on ethanol consumption, basal behaviors, and modulation of GSK3B targets.
Methods: C57BL/6J males and females received i.g. 200mg/kg tideglusib, except drinking-in-the-dark (males;100mg/kg i.p.). Drinking-in-the-dark (DID): Mice given 20% ethanol 4-hours, 4-days/week x 3 weeks and then i.p. tideglusib or vehicle x 4 days in a Latin Square design with ethanol consumption measured daily. Light/Dark Box: Mice gavaged with tideglusib or vehicle …
Comparison Of Free Versus Encapsulated Drugs On 3t3 Differentiation, Simon H. Friedrich, Gabriel Volpe
Comparison Of Free Versus Encapsulated Drugs On 3t3 Differentiation, Simon H. Friedrich, Gabriel Volpe
Undergraduate Research Posters
The scope of this project was to design, synthesize and test targeted nanoparticles containing hydrophobic and hydrophilic drugs that promote browning in adipose tissue. For hydrophilic drugs the use of liposomes and their hydrophilic core is more useful than the PLGA nanoparticles which have hydrophobic cores. The inhibition of the FOXO1 pathway and modulation of autophagy in adipose tissue can promote browning of white adipose tissue, or an energy burning state where excess energy is burned as heat instead of stored in the cell. If successful, these drugs would offer an alternative treatment for obesity where changes to the patient's …
The Water Solubility Of Ursolic Acid Complexes At Different Choline Concentrations, Sera Lim, Renjie Zhan, Phillip M. Gerk
The Water Solubility Of Ursolic Acid Complexes At Different Choline Concentrations, Sera Lim, Renjie Zhan, Phillip M. Gerk
Undergraduate Research Posters
No abstract provided.
Modified Ysk12-Mend-Sirna In Dendritic Cells For Cancer Immunotherapy, Syed S. Alam
Modified Ysk12-Mend-Sirna In Dendritic Cells For Cancer Immunotherapy, Syed S. Alam
Undergraduate Research Posters
Tumors may induce tolerogenesis through signaling dendritic cells to produce tolerogenic molecules, such as indoleamine 2, 3-dioxygenase 1 (IDO1). Tumor-associated immunosuppression is associated with higher mortality in patients. Small interfering RNA (siRNA) has been shown to silence specific target genes in the target cell. The siRNA associated with these genes could support a gene knockdown of these immunosuppressors and reduce mortality. Delivery of these therapeutic nucleic acids is difficult in vivo because siRNA is easily broken down inside the cell and the bloodstream through present nucleases. Use of liposome polymers has been reviewed extensively in literature. YSK12-C4, a lipid nanoparticle …
Combine Cryo-Em Density Map And Residue Contact For Protein Structure Prediction: A Case Study, Maytha Alshammari, Jing He
Combine Cryo-Em Density Map And Residue Contact For Protein Structure Prediction: A Case Study, Maytha Alshammari, Jing He
College of Sciences Posters
Although atomic structures have been determined directly from cryo-EM density maps with high resolutions, current structure determination methods for medium resolution (5 to 10 Å) cryo-EM maps are limited by the availability of structure templates. Secondary structure traces are lines detected from a cryo-EM density map for α-helices and β-strands of a protein. A topology of secondary structures defines the mapping between a set of sequence segments in 1D and a set of traces of secondary structures in 3D. In order to enhance the accuracy in ranking secondary structure topologies, we propose a method that combines three sources of information …
Drug Loaded Mesoporous Nanocarriers For The Treatment Of Aspergilliosis, Madeline Brooks, Emily Hunt
Drug Loaded Mesoporous Nanocarriers For The Treatment Of Aspergilliosis, Madeline Brooks, Emily Hunt
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
Improving Purification Method Of The F-Plasmid Exclusion Protein Trat, Jazmyn Whitfield, Katelyn Lott, Victor Dunagan
Improving Purification Method Of The F-Plasmid Exclusion Protein Trat, Jazmyn Whitfield, Katelyn Lott, Victor Dunagan
Summer Community of Scholars Posters (RCEU and HCR Combined Programs)
No abstract provided.
The Inhibition Of Growth Of S. Cerevisiae, U. Maydis, And M. Lychinidis-Dioicae By Apiaecea Plant Extracts, Jackson M Hoffman, Jared Scott, David Schultz Phd
The Inhibition Of Growth Of S. Cerevisiae, U. Maydis, And M. Lychinidis-Dioicae By Apiaecea Plant Extracts, Jackson M Hoffman, Jared Scott, David Schultz Phd
Undergraduate Arts and Research Showcase
The Apiaceae family of plants contains over 3,500 species, many of which are used as food crops: vegetables (carrot, parsnip, celery, etc.), herbs (cilantro, fennel, dill, etc.), and spices (cumin, anise, caraway, etc.). Many spices have been shown to exhibit antimicrobial properties against both bacteria and fungi. We set out to determine if the Apiaceae spice extracts currently used in our lab for anticancer studies exhibit any antimicrobial properties. Ethanolic extracts were made from several Apiaceae seeds: Apium graveolens (celery), Cuminum cyminum (cumin), Anethum graveolens(dill), Foeniculum vulgare (fennel), Coriandrum satvium (coriander), Pimpinella ansium (anise), Trachyspermum ammi (ajwain), Carum carvi …
Transcriptional Repressor Protein Based Macrolide Biosensor Development With Improved Sensitivity, Jayani A. Christopher
Transcriptional Repressor Protein Based Macrolide Biosensor Development With Improved Sensitivity, Jayani A. Christopher
Graduate Research Posters
Macrolide antibiotics are in high demand for clinical applications. Macrolides are biosynthesized via giant assembly line polyketide synthases (PKS) which are arranged in a modular fashion. Combinatorial biosynthetic methods have been used to produce diversified macrolides by reprograming these modules and modifying tailoring enzymes required for post synthetic modifications. However it is challenging due to the size and complexity of PKSs. To overcome this challenge, new enzymes for macrolide diversification could be obtained by directed evolution where a large number of enzyme variants need to be screened. Therefore it is important to develop high throughput screening methods to identify the …
Wolfer Drug Store Collection, 1878-1884, Special Collections, Leonard H. Axe Library
Wolfer Drug Store Collection, 1878-1884, Special Collections, Leonard H. Axe Library
Finding Aids
A collection of ledgers from Wolfer Drug Store in Yates Center during the 1870s-1880s.
Wolfer Drug Store was started by James M. Wolfer (c1852-?), the first drug store in Yates Center, Kansas and was the third store in the town. Yates Center, the county seat of Woodson County, was founded in 1875 and named after the original owner of the town site, Abner Yates. In 1880, the store was sold to Dr. Samuel Jewett Bacon (1847-1908) who operated the store until the early 1900s.
Hailey-Hailey Disease Successfully Treated With Low-Dose Naltrexone, John Moesch, Richard Miller
Hailey-Hailey Disease Successfully Treated With Low-Dose Naltrexone, John Moesch, Richard Miller
West Florida Division Virtual Research Day 2020
Hailey-Hailey disease (HHD) is an uncommon autosomal dominant disorder resulting from a mutation in the ATP2C1 gene resulting in dysfunction of the Golgi apparatus calcium-associated ATPase, thus interfering with intercellular calcium signaling.
HHD presents clinically as flaccid blisters and erosions in intertriginous areas, especially the axillae and groin.
The major histologic finding is acantholysis throughout the spinous layer of the epidermis, commonly referred to as a “dilapidated brick wall” appearance.
The initial lesions and associated symptoms usually develop during the second or third decade of life.
Complications of HHD include infections (bacterial, fungal, and viral), and malignant transformation (cutaneous squamous …
Is There An Innovative Solution To The Opioid Epidemic?, Maggie Schray
Is There An Innovative Solution To The Opioid Epidemic?, Maggie Schray
Student Research Poster Presentations 2020
There are innovative ways and solutions to the current opioid epidemic. This affects people of every walk of life and is a huge problem in our country.
Pediatric Surgery Opioid Prescription Follow-Up, Gadison Quick, Nathaniel Aviles, Gabriel Melgarejo, Hunjung Choi, Elizabeth Edmundson
Pediatric Surgery Opioid Prescription Follow-Up, Gadison Quick, Nathaniel Aviles, Gabriel Melgarejo, Hunjung Choi, Elizabeth Edmundson
Posters
This quality improvement project is assisting general and orthopedic surgeons in gaining greater clarity when prescribing opioids for specific surgical procedures. Additional surgical services are being added to the project fall of 2019. Opioid prescribing patterns are, and will continue to be, key to all prescribing providers within our organization.
Optimizing Antibiotic Management Of Pediatric Acute Otitis Media In An Emergency Department, Alicia Daggett, Alaina N. Burns, Brian R. Lee, Nirav Shastri, Patricia Phillips, Rana E. El Feghaly
Optimizing Antibiotic Management Of Pediatric Acute Otitis Media In An Emergency Department, Alicia Daggett, Alaina N. Burns, Brian R. Lee, Nirav Shastri, Patricia Phillips, Rana E. El Feghaly
Posters
Problem
Children diagnosed with acute otitis media (AOM) at the Children's Mercy Hospital Kansas Emergency Department routinely get antibiotic prescriptions. There is rarely discussion with families about watchful waiting (defined as discussion of observation with parents and providing a safety-net antibiotic prescription that parents can ill if the patient is not improving or is worsening over the next 48 hours).
The aim of this quality improvement project is to increase watchful waiting for AOM at the CMK ED by 20% by March 2020, with an overall goal of decreasing antibiotic use for AOM.