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Analytical, Diagnostic and Therapeutic Techniques and Equipment

William & Mary

Theses/Dissertations

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Full-Text Articles in Medicine and Health Sciences

Machine Learning In Healthcare: Improving The Diagnosis Of Pulmonary Embolism In Covid-19 Patients, Soheb Osmani Apr 2022

Machine Learning In Healthcare: Improving The Diagnosis Of Pulmonary Embolism In Covid-19 Patients, Soheb Osmani

Undergraduate Honors Theses

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created new challenges for clinicians diagnosing pulmonary embolism (PE). Clinicians currently rely on D-Dimer levels in conjunction with clinical prediction scores to rule out and diagnose PE. However, patients with COVID-19 (the disease caused by SARS-CoV-2) often present with elevated D-Dimer levels. D-Dimer levels in COVID-19 patients have been found to be positively correlated with the severity of disease. Symptoms of COVID-19 also often align with symptoms of PE. Therefore, it becomes more difficult for clinicians to identify which COVID-19 positive patients should undergo further testing for PE. This study evaluates …


On The Real-Time Performance, Robustness And Accuracy Of Medical Image Non-Rigid Registration, Yixun Liu Jan 2011

On The Real-Time Performance, Robustness And Accuracy Of Medical Image Non-Rigid Registration, Yixun Liu

Dissertations, Theses, and Masters Projects

Three critical issues about medical image non-rigid registration are performance, robustness and accuracy. A registration method, which is capable of responding timely with an accurate alignment, robust against the variation of the image intensity and the missing data, is desirable for its clinical use. This work addresses all three of these issues. Unacceptable execution time of Non-rigid registration (NRR) often presents a major obstacle to its routine clinical use. We present a hybrid data partitioning method to parallelize a NRR method on a cooperative architecture, which enables us to get closer to the goal: accelerating using architecture rather than designing …


Targeting The Sodium Iodide Symporter For In Vivo Detection And Characterization Of Mammary Tumors In The Murine Model Using A Novel Gamma Camera, Randall Eric Blue Jan 2009

Targeting The Sodium Iodide Symporter For In Vivo Detection And Characterization Of Mammary Tumors In The Murine Model Using A Novel Gamma Camera, Randall Eric Blue

Dissertations, Theses, and Masters Projects

No abstract provided.


A Versatile Imaging System For In Vivo Small Animal Research, Jianguo Qian Jan 2008

A Versatile Imaging System For In Vivo Small Animal Research, Jianguo Qian

Dissertations, Theses, and Masters Projects

In vivo small animal imaging has become an essential technique for molecular biology studies. However, requirements of spatial resolution, sensitivity and image quality are quite challenging for the development of small-animal imaging systems. The capabilities of the system are also significant for carrying out small animal imaging in a wide range of biological studies. The goal of this dissertation is to develop a high-performance imaging system that can readily meet a wide range of requirements for a variety of small animal imaging applications. Several achievements have been made in order to fulfill this goal.;To supplement our system for parallel-hole single …


Dual Energy Scanning Beam X -Radiography, Randolph Frank Wojcik Jan 2004

Dual Energy Scanning Beam X -Radiography, Randolph Frank Wojcik

Dissertations, Theses, and Masters Projects

Dual energy X-radiography is a method first developed in the mid-1970's by which one uses the information contained in the energy spectrum of the transmitted X-ray flux through an object. With this information one can distinguish the types of materials present in a radiograph and thus allow a computer to subtract them from the image enhancing the contrast of the remaining materials. Using this method, one can see details, which would have been hidden by overlying structures of other materials such as seen in radiographs of parts, made up of mixtures of metals and composites. There is also great interest …


Ultrasonographic Measurement Of Periodontal Attachment Levels, John Edward Lynch Jan 2001

Ultrasonographic Measurement Of Periodontal Attachment Levels, John Edward Lynch

Dissertations, Theses, and Masters Projects

Periodontal disease is one of the two major causes of tooth loss today, and has been associated with several systemic diseases, such as diabetes, cardiovascular disease, stroke, and adverse pregnancy outcomes. Unfortunately, the most widely used diagnostic tool for assessment of periodontal diseases, measurement of periodontal attachment loss with a manual probe, may overestimate attachment loss by as much as 2mm in untreated sites, while underestimating attachment loss by an even greater margin following treatment. Manual probing is also invasive, which causes patient discomfort.;This work describes the development and testing of an ultrasonographic periodontal probe designed to replace manual probing. …


Gamma-Ray Imaging Detector For Small Animal Research, Andrew Gerard Weisenberger Jan 1998

Gamma-Ray Imaging Detector For Small Animal Research, Andrew Gerard Weisenberger

Dissertations, Theses, and Masters Projects

A novel radiation imaging technology for in vivo molecular imaging in small mammals is described. The goal of this project is to develop a new type of imaging detector system suitable for real-time in vivo probe imaging studies in small animals. This technology takes advantage of the gamma-ray and x-ray emission properties of the radioisotope iodine 125 (125I) which is employed as the label for molecular probes. The radioisotope 125I is a gamma-ray emitting radioisotope that can be commercially obtained already attached to biomedically interesting molecules to be used as tracers for biomedical and molecular biology research.;The isotope 125I decays …


Calculations Of The Interactions Of Energetic Ions With Materials For Protection Of Computer Memory And Biological Systems, Myung-Hee Y. Kim Jan 1995

Calculations Of The Interactions Of Energetic Ions With Materials For Protection Of Computer Memory And Biological Systems, Myung-Hee Y. Kim

Dissertations, Theses, and Masters Projects

Theoretical calculations were performed for the propagation and interactions of particles having high atomic numbers and energy through diverse shield materials including polymeric materials and epoxy-bound lunar regolith by using transport codes for laboratory ion beams and the cosmic ray spectrum. Heavy ions fragment and lose energy upon interactions with shielding materials of specified elemental composition, density, and thickness. A fragmenting heavy iron ion produces hundreds of isotopes during nuclear reactions, which are treated in the solution of the transport problem used here. A reduced set of 80 isotopes is sufficient to represent the charge distribution, but a minimum of …