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Mechanisms Of T Helper Cell Modulation In A Simulated Space Radiation Environment, Asma Rizvi
Mechanisms Of T Helper Cell Modulation In A Simulated Space Radiation Environment, Asma Rizvi
Loma Linda University Electronic Theses, Dissertations & Projects
Exposure to solar particle events (SPEs) poses the most serious threat to astronaut health. Due to this radiation environment, exploration of the solar system beyond Earth’s orbit entails many risks for the crew on these deep space missions. Depression or dysfunction of the immune system is a major concern due to its high radio-sensitivity; potential consequences include overwhelming infection, development of cancer, fibrosis, and poor wound healing. Astronauts are also exposed to low dose/low dose rate (LDR) radiation. A three month stay at the international space station exposes them to ~ 0.05 Gy of radiation.
C57BL/6 mice received LDR gamma-radiation …