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Articles 1 - 8 of 8
Full-Text Articles in Physiology
Examining The Function Of Protein Acyltransferase Via The Dhhc Domain Of The Paz5 Protein In The Organism Dictyostelium Discoideum, George M. Stuart-Ranchev
Examining The Function Of Protein Acyltransferase Via The Dhhc Domain Of The Paz5 Protein In The Organism Dictyostelium Discoideum, George M. Stuart-Ranchev
Electronic Theses and Dissertations
Protein S-palmitoylation plays a crucial role in many biological systems. S-palmitoylation involves the post-translational attachment of palmitate to a cysteine residue through a reversible thioester linkage. S-Palmitoylation is used to modify both integral and membrane proteins, many of which are involved in intracellular trafficking, membrane localization, and signal transduction pathways. Intracellular palmitoylation is mediated by a family of protein acyltransferases (PATs). PAT mutations are associated with neurological diseases and cancer progression. Proteins in the PAT family are defined by the presence of a 51-amino acid cysteine-rich domain (CRD), which contains a highly conserved aspartate-histidine-histidine-cysteine (DHHC) motif. The …
Biophysical And Stable Isotopic Profiles Of The Salmon Louse Lepeophtheirus Salmonis (Krøyer, 1837), Emma Taccardi
Biophysical And Stable Isotopic Profiles Of The Salmon Louse Lepeophtheirus Salmonis (Krøyer, 1837), Emma Taccardi
Electronic Theses and Dissertations
The salmon louse Lepeophtheirus salmonis is a parasitic copepod that infects wild and farmed salmonids throughout the northern hemisphere. L. salmonis represents the largest economic hurdle of the Atlantic salmon (Salmo salar) industry, with an estimated annual cost of nearly $1 billion globally due to production losses and anti-parasitic control measures. Salmon farming in Maine has existed for decades and is a critical economic driver, yet the region is underrepresented in global sea lice research. The aim of this work was to examine parasites in the context of animal trophic transfer and characterize physiological condition by quantifying the …
Zebrafish As A Model To Understand The Impact Of Inactivity And Neuromuscular Electrical Stimulation On Duchenne Muscular Dystrophy, Elisabeth Kilroy
Zebrafish As A Model To Understand The Impact Of Inactivity And Neuromuscular Electrical Stimulation On Duchenne Muscular Dystrophy, Elisabeth Kilroy
Electronic Theses and Dissertations
Skeletal muscle plasticity is imperative for functional adaptation to changing demands in activity. Although a great deal is known about the structural and functional plasticity of healthy skeletal muscle, far less is known about plasticity in diseased muscle. Here, we combined the power of the zebrafish model with the adaptability of neuromuscular electrical stimulation (NMES) to study the basic mechanisms of plasticity in the zebrafish model of Duchenne Muscular Dystrophy (DMD). Four NMES paradigms, defined by their frequency, delay, and voltage, were designed to emulate the repetition and load schemes of human resistance training programs. Additionally, two inactivity paradigms were …
Bilateral Muscle Oxygenation Kinetics In Response To Repeat Sprint Cycling In Strong And Weak Individuals, John Abbott
Bilateral Muscle Oxygenation Kinetics In Response To Repeat Sprint Cycling In Strong And Weak Individuals, John Abbott
Electronic Theses and Dissertations
Repeat sprint ability has been investigated thoroughly, however optimal training methodology to improve RSA remains elusive. Both kinetic and physiological viewpoints have been used to scrutinize aspects of RSA including, initial sprint performance (anaerobic power), maximal cardiorespiratory fitness (VO2max), lactate threshold, anaerobic capacity (mean power), muscle activation (EMG), and local muscle oxygenation kinetics. To our knowledge no study has utilized maximal strength levels as a separate factor among a homogenous group of cardiorespiratory fitness individuals (as determined by peak VO2 during RSA). The purpose of this study was to better understand the relationship between maximal strength, muscular characteristics, and cycling …
Compensatory Inactivity In Female Collegiate Soccer Players, Caylee Costello
Compensatory Inactivity In Female Collegiate Soccer Players, Caylee Costello
Electronic Theses and Dissertations
Objective: To measure the physical activity levels of Division I collegiate female soccer players with the use of accelerometers to help determine compensatory changes and help establish appropriate training rhythms through the course of a season.
Design: 25 female Division I soccer players volunteered to participate in a 7-day observational study. Players wore an ActiGraph GT3X+ accelerometer during waking hours. Five second epochs were recorded and age appropriate physical activity cut points were used to determine the minutes of sedentary time (ST), light physical activity (LPA), moderate physical activity (MPA), vigorous physical activity (VPA) and moderate to vigorous physical activity …
Plasticity And The Impact Of Increasing Temperature On A Tropical Ectotherm, Adam A. Rosso
Plasticity And The Impact Of Increasing Temperature On A Tropical Ectotherm, Adam A. Rosso
Electronic Theses and Dissertations
Organisms may respond to climate change through behavior, genetic adaptation, and/or phenotypic plasticity. Tropical ectotherms are thought to be especially vulnerable to climate change because most have a narrow range of thermal tolerance while living close to their upper thermal tolerance limits. Additionally, many tropical species live in closed-canopy forests, which provide homogenous thermal landscapes that prevent behavioral compensation for stressfully warm temperatures. Finally, tropical ectotherms are thought to have decreased capacity for phenotypic plasticity because they have evolved in thermally stable environments. We tested gene expression patterns and phenotypic plasticity in the Panamanian slender anole by a) measuring changes …
Physiological Response Of Elasmobrachs During Propofol Immersion, Matthew Levendosky
Physiological Response Of Elasmobrachs During Propofol Immersion, Matthew Levendosky
Electronic Theses and Dissertations
Sensory experiments require anesthesia so the animal is immobilized, however fish anesthetics have shown to depress sensory responses. Newer anesthetics may offer similar anesthetic relief, but differ in means of action so sensory responses may be unaffected. Propofol has been used intravenously on small elasmobranchs but may provide prolonged effects if used as an immersion anesthetic. Objectives of this study were 1. Determine appropriate concentration of anesthetic to minimize induction and recovery for animals anesthetized at a surgical plane of anesthesia and 2. Measure physiological response of the pupil to light stimuli during anesthetic immersion. To address these objectives, I …
Characterization And Effects Of Systemic And Ovarian Gnrh In Beef Cattle, Jerica J. J. Rich
Characterization And Effects Of Systemic And Ovarian Gnrh In Beef Cattle, Jerica J. J. Rich
Electronic Theses and Dissertations
Previous studies evaluating single and multiple GnRH injections at time of CIDR removal/prostaglandin injection using the 7-day CO-Synch + CIDR protocol have reported decreased interval to estrus and increased expression of estrus, or increased conception rates, respectively. Thus, the objective of experiment 1 (Chapter 3) was to compare the effects of supplementing GnRH at prostaglandin injection on expression of estrus and conception rates in beef cows and heifers synchronized with different protocols. The objective was conducted in two parts, in study 1, Beef cows (n = 161) and heifers (n = 1803) from 16 herds over three years were synchronized …