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Full-Text Articles in Physiology
Effects Of Single Weekly Bout Of Exercise On Cell Proliferation During The Rat Colon Carcinogenesis, Tassiana Marini, Cleverson Rodrigues Fernandes, Fernando Tadeu Frajacomo, Marcelo Marcos Piva Demarzo
Effects Of Single Weekly Bout Of Exercise On Cell Proliferation During The Rat Colon Carcinogenesis, Tassiana Marini, Cleverson Rodrigues Fernandes, Fernando Tadeu Frajacomo, Marcelo Marcos Piva Demarzo
International Journal of Exercise Science: Conference Proceedings
There is evidence that the risk of colon cancer is reduced by appropriate levels of physical exercise. However, the effects of single weekly bout of exercise are largely unknown. Our aim was to verify the effects of exercise once a week (1d-wk-1) and daily exercise training (5d-wk-1) in rats treated with the carcinogen 1-2- Dimethyl-hydrazine (DMH). Forty-two Wistar rats were used in the experiment. The groups G1 and G2 were sedentary (controls), the groups G1A and G2A were submitted 1d-wk-1 of swimming, and G1B and G2B were submitted 5d-wk-1 of swimming training for 8 weeks. The groups G2, G2A and …
Continuous Light Reverts Physical Exercise Effects On Colon Carcinogenesis Induced By 1,2-Dimethyl-Hydrazine In Rats, Fernando Tadeu Trevisan Frajacomo, Cleverson Rodrigues Fernandes, Ana Paula Farnesi, Tassiana Marini
Continuous Light Reverts Physical Exercise Effects On Colon Carcinogenesis Induced By 1,2-Dimethyl-Hydrazine In Rats, Fernando Tadeu Trevisan Frajacomo, Cleverson Rodrigues Fernandes, Ana Paula Farnesi, Tassiana Marini
International Journal of Exercise Science: Conference Proceedings
Colon cancer risk is reduced by appropriate levels of physical exercise. Light exposure during the night conveys endocrine changes on melatonin rhythm produced by pineal gland. This hormone is considered as a potent anti-oxidant with oncostatic properties. Both factors are related to colon cancer, which risk can be estimated by the evaluation of pre-malignant factors of colonic mucosa such as the Aberrant Crypt Foci (ACF). This study aims to verify whether the beneficial effects of physical exercise are related to the activity of the pineal gland. Thus, 40 rats were divided into 5 groups: G0, G1 and G2 were sedentary, …
Exercise In Colon Cancer Modulation: An Experimental Approach, Marcelo M. P. Demarzo, Sérgio B. Garcia, Sérgio E. A. Perez
Exercise In Colon Cancer Modulation: An Experimental Approach, Marcelo M. P. Demarzo, Sérgio B. Garcia, Sérgio E. A. Perez
International Journal of Exercise Science: Conference Proceedings
Carcinogenesis is a complex process best characterized as an accumulation of alterations in genes regulating cellular homeostasis. The whole process can be divided into three main stages: initiation, promotion, and progression. It has been observed that moderate and regular physical activity (PA) may prevent cancer, mainly colon cancer (CC), up to 50% in humans. The evidence that PA protects against colon cancer is convincing. Also, PA probably protects against postmenopausal breast cancer and cancer of the endometrium. On the other hand, exhaustive exercise increases free radical DNA oxidative damage, inflammation and depresses immune function, events also related to the increased …