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Full-Text Articles in Physiology

Effect Of Estrogen Pretreatment On Glial-Like Cell Viability Following Stress Response Hormone Treatment, Bridget N. Smith, Kevin S. Burgess, Kathleen S. Hughes Nov 2021

Effect Of Estrogen Pretreatment On Glial-Like Cell Viability Following Stress Response Hormone Treatment, Bridget N. Smith, Kevin S. Burgess, Kathleen S. Hughes

Georgia Journal of Science

The role of steroid hormones is critical in cellular function. Previous studies have found a positive correlation between the endogenous estrogen 17β-estradiol and cellular protection. Conversely, exogenous conjugated equine estrogens provide less protective mechanisms than endogenous hormones, and little is known about the role of estrogens in cellular protection during a stress response. In the present study, we compare the effects of short-term estrogen pretreatments (alone and in combination) on cell viability when cells with glial cell morphology are exposed to either epinephrine or cortisol. Results showed that 1 µM 17β-estradiol resulted in decreased cell viability following the epinephrine treatment; …


The Effects Of Fluoride Ions On Neuromuscular Activity And Regeneration In Dugesia Tigrina, John Williams Jr. Jun 2017

The Effects Of Fluoride Ions On Neuromuscular Activity And Regeneration In Dugesia Tigrina, John Williams Jr.

Georgia Journal of Science

Fluoride ions have been implicated in numerous nervous system pathologies, though the association of these ions with these conditions has been controversial. The purpose of this research is to determine the effects that fluoride ions have on the nervous system development and function in planarians as a simple model for fluoride-nervous system interactions. In the first set of experiments, planarians were exposed to one of four concentrations of sodium fluoride: 0 mM, 1 mM, 1 mM, and 5 mM. In the second set of experiments, planarians were bisected and exposed to 1 mM of NaCl and NaF for regeneration purposes. …