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Full-Text Articles in Physiology
Rage Functions During Secondhand Smoke-Induced Bronchopulmonary Dysplasia, Brent Kimber, Dr. Paul Reynolds
Rage Functions During Secondhand Smoke-Induced Bronchopulmonary Dysplasia, Brent Kimber, Dr. Paul Reynolds
Journal of Undergraduate Research
Bronchopulmonary Dysplasia (BPD) is a common respiratory disease among pre-term infants or newborns exposed to harmful toxins during pregnancy or at birth. This leads to several respiratory diseases later in life such as chronic obstructive pulmonary disorder (COPD) or asthma. However, research on the effects of cigarette smoke in utero has many gaps. This project focuses on developing a transgenic mouse model that mimics the pulmonary morphologies and characteristics of BPD. This model will then be used for further research and potentially discover new therapeutic methods for BPD. The transgenic mouse was established using a modified genetic scheme whereby the …