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Physiology Commons

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Journal of Undergraduate Research

Journal

2016

Biophysical actions

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Full-Text Articles in Physiology

Biophysical Actions Of Nsaids And Volatile Anesthetics, David D. Busath Mar 2016

Biophysical Actions Of Nsaids And Volatile Anesthetics, David D. Busath

Journal of Undergraduate Research

This award led to a wonderful confluence of mentored research experiences for 9 undergraduates and 1 graduate student. The academic goal was to evaluated the role of NSAIDs and general anesthetics in modulating lipid bilayer mechanics, particularly as they influenced pressure area curves and dye absorption rates in purified lipid vesicles. The studies were augmented and informed by molecular dynamics simulations of such molecules being positioned at different levels in the lipid bilayer and measuring the average normal force on the molecules.