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Full-Text Articles in Physiology
Circadian Regulation Of The Timing Of Pre-Ovulatory Luteinizing Hormone Surge In Mice And Hamsters, Ajay Kumar
Circadian Regulation Of The Timing Of Pre-Ovulatory Luteinizing Hormone Surge In Mice And Hamsters, Ajay Kumar
Doctoral Dissertations
Endogenous daily (circadian) oscillators ensure the proper timing of physiological and behavioral processes that are essential to health. A set of core clock genes and their protein products function in transcriptional/translational feedback loops (TTFLs) that time and coordinate vital homeostatic, cognitive, and hormonal processes. A master pacemaker in the suprachiasmatic nucleus (SCN) coordinates circadian function throughout the organism. Investigating the causal role of genetically defined cell types in the suprachiasmatic nucleus for circadian rhythms is essential to understand how an animal’s physiology is temporally organized. This thesis explores the role of molecular clocks within particular cell types in regulating physiology. …