Physiology Commons^™

Recycling Of Deuterium From Dideuterated Glucose During Moderate Exercise, Michael A. Horning, Sheri R. Colberg, Gretchen A. Casazza, George A. Brooks

Educational Foundations & Leadership Faculty Publications

A doubly labelled tracer molecule of glucose, [6,6^-2HJglucose, has been used to measure the rate of glucose appearance in blood due to endogenous glucose production (by the liver and kidneysj.^l,2 Considered 'non-recirculating', this tracer generally provides a realistic estimate of glucose kinetics.^2,3 Used as a dual tracer in conjunction with [l-¹³C]glucose, the extent of glucose recycling can be quantitated.^2-4 but the extent of possible recirculation of a single deuterium atom on newly formed glucose must then be considered.