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Full-Text Articles in Physiology
Elucidating The Role Of The Transcriptional Co-Activator Camta1 In Cardiac Development, Nate Batey, Zach Frederich, Morgan Fronk, Nate Jenkins, Jonathon Hill
Elucidating The Role Of The Transcriptional Co-Activator Camta1 In Cardiac Development, Nate Batey, Zach Frederich, Morgan Fronk, Nate Jenkins, Jonathon Hill
Journal of Undergraduate Research
Congenital Heart Disease (CHD) is the most common type of birth defect in the United States, causing more first-year infant deaths than any other birth defect (1). While the causes of CHD are varied, genetic defects are known to play a significant role. Identifying and studying genes involved in embryonic heart development can enhance understanding of the genetic factors in CHDs. The camta1 gene is a promising candidate due to its transient expression in heart morphogenesis and its relationship to camta2 , the only other member of its family in vertebrates and a known player in adult heart failure (2,3).