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Full-Text Articles in Physiology

Integrative Physiology-Coupled Pilot-Centered Flight Simulation, Shawn C. Harrison Dec 2022

Integrative Physiology-Coupled Pilot-Centered Flight Simulation, Shawn C. Harrison

Electrical & Computer Engineering Theses & Dissertations

Maintaining the pilot’s physiological performance envelope within the limits of human capabilities may be crucial for avoiding hazardous physiological episodes in fighter aircraft that compromise safety. The main physiological episode of interest is impaired pilot respiration, better known as hypoxia caused by a high fraction of inspired oxygen (FiO2) at high altitudes and variation in accelerative gravitational forces (g-forces). Integrated into fighter aircraft is an Onboard Oxygen Generating System (OBOGS) developed to mitigate the necessity of gaseous and liquid oxygen cannisters [1]. OBOGS act as a life support in hypoxic environments by providing oxygen-rich air, thereby oxygenating the …


Engineering Of Ideal Systems For The Study And Direction Of Stem Cell Asymmetrical Division And Fate Determination, Martina Zamponi Aug 2022

Engineering Of Ideal Systems For The Study And Direction Of Stem Cell Asymmetrical Division And Fate Determination, Martina Zamponi

Biomedical Engineering Theses & Dissertations

The cellular microenvironment varies significantly across tissues, and it is constituted by both resident cells and the macromolecules they are exposed to. Cues that the cells receive from the microenvironment, as well as the signaling transmitted to it, affect their physiology and behavior. This notion is valid in the context of stem cells, which are susceptible to biochemical and biomechanical signaling exchanged with the microenvironment, and which plays a fundamental role in establishing fate determination and cell differentiation events. The definition of the molecular mechanisms that drive stem cell asymmetrical division, and how these are modulated by microenvironmental signaling, is …


The Associations Of Cardiovascular Disease, Physical Activity Intensities, And Measures Of Obesity On Static Balance In Middle-Aged And Older Adults, Hannah Martha Twiddy May 2022

The Associations Of Cardiovascular Disease, Physical Activity Intensities, And Measures Of Obesity On Static Balance In Middle-Aged And Older Adults, Hannah Martha Twiddy

Human Movement Sciences & Special Education Theses & Dissertations

The burden of falls is widely known in older adults, though less research has targeted middle-aged adults (40-64 years of age), particularly at the population level. The purpose of this dissertation was to explore the roles of cardiovascular disease, physical activity (PA) intensity, and body anthropometrics on balance among middle-aged adults. Study 1 sought to determine if balance was impaired in middle-aged adults with poor ankle-brachial pressure index (ABPI), a marker of cardiovascular disease. Study 2 determined the associations between PA intensity with odds of having good static balance. Study 3 explored how strongly a variety of anthropometric measures, including …