Physiology Commons^™

Evaluating A Current Athlete Assessment Program, David Fish

Electronic Theses and Dissertations

The primary purpose of this dissertation is to evaluate the effectiveness of a questionnaire designed to assess coaches’ perceptions of an athlete monitoring program. There are four reasons for this examination of perceptions: 1) it may serve as a check for understanding of how the coach takes in the information presented to them, 2) identify any gaps in the knowledge of the coach which the sport scientist may help to fill, 3) can serve to open a dialog with the coach for ways in which the information may be better tailored to help them improve their decision-making, and 4) the …

Effects Of Blood Flow Restriction During Acute Multi-Joint Eccentric Exercise On Muscle Recovery, Cody Fisher

All Graduate Reports and Creative Projects, Fall 2023 to Present

Blood flow restriction (BFR) exercise has become an increasingly common modality due to evidence that it may yield positive muscle-related effects from low-intensity exercise. However, eccentric-only exercise in a multi-joint format has not yet been investigated in regard to the BFR influence on muscle recovery characteristics. The purpose of this study was to assess muscle recovery responses via isometric peak force (PF), soreness (i.e., VAS, PPT, PPD), and functional power (i.e., SLHD) following a 5-minute low-load multi-joint eccentric exercise bout with or without blood flow restriction. Thirty participants were randomly assigned into either an eccentric-only (CON) or an eccentric BFR …

Asymmetries In Ncaa Division I Tennis Players Compared To An Athletic Control Group, Elizabeth Cafferty

All Graduate Reports and Creative Projects, Fall 2023 to Present

Limb asymmetries are an expected adaptation to years of training for athletes participating in dominant-sided sports. Previous research on this topic lacks an athletic control group. PURPOSE: To determine the magnitude of upper limb asymmetries in dominant-sided athletes (tennis players) compared to nondominant-sided athletes (cross-country runners). METHODS: Male and female NCAA Division I athletes (10 tennis, 11 cross-country) participated. Dual-energy x-ray absorptiometry (DXA) was used to measure bone mineral content (BMC), bone mineral density (BMD), and lean mass (LM) of the whole body, upper extremities, and forearms. Circumference measurements were taken at mid-biceps and the widest part of the forearms. …

Cultivating Excellence: A Literature Review On Harnessing The Power Of The Gut Microbiome For Athletic Performance, Maya Katharine Dean

Honors Projects

The interplay between our gut microbiome and health is immense. This literature review analyzes the current research assessing the interplay between gut microbiome and athletic performance. Knowing how to improve gut microbial diversity via nutrition and supplementation can take athletic performance to the next level; namely improvements in immune, mental, and physical health.

The Effect Of Step Rate Training On Running Economy And Biomechanics, Nahir Negron-Fernandez

All NMU Master's Theses

It is known that running economy is a determinant of running performance. Increased step rate has been correlated with improved running economy, but it is unknown whether these improvements can be maintained with chronic training. The purpose of this study was to determine if a step rate training intervention improves running economy and improves lower body kinetic factors in distance runners. Nine participants were randomly assigned to either an intervention group (n = 7) undergoing a 6-week supplemental training program, or a non-training control group (n = 2). The intervention group trained three times a week, running at a higher …

Effect Of Metabolic Rate On Mitochondrial Efficiency During Exercise In Human Skeletal Muscle In Vivo, Muhammet Enes Erol

Masters Theses

Introduction: Recent evidence in isolated mitochondria and permeabilized muscle fibers in ex vivo using simultaneous measurements of O₂ consumption and ATP production suggest that mitochondrial efficiency provides an additional mechanism to fine-tune oxidative phosphorylation rate to ATP demand in skeletal muscle. However, in the absence of a direct measurement of both VO₂ and ATP synthesis from the same region of the contracting muscle, whether this mechanism plays a role in the skeletal muscle in vivo is still unknown. Purpose: Using a noninvasive approach combining phosphorus and proton magnetic resonance spectroscopy (³¹P/¹H-MRS), the present study …

Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz

Health, Exercise, and Sports Sciences ETDs

Aging and excess post-exercise oxygen consumption (EPOC) is something that has not been adequately studied. Studies looking at EPOC mostly are compiled of young college age individuals. Aging in humans is a topic of much research with still more to be learned. The study in this paper attempts to answer the question of whether age affects EPOC when performing a certain exercise. Preliminary findings based on general age-related research suggest the possibility. This thesis will explore the current research related to age and EPOC, analyze the findings, and discuss additional avenues for future research.

Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian

Master's Theses

As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …

The Effects Of Resistance Exercise Training On Insulin Resistance Development In Female Rodents With Type 1 Diabetes, Mitchell James Sammut

Electronic Thesis and Dissertation Repository

The etiology of insulin resistance (IR) development in type 1 diabetes mellitus (T1DM) remains unclear; however, impaired skeletal muscle metabolism may play a role. While IR development has been established in male T1DM rodents, female rodents have yet to be examined in this context. Resistance exercise training (RT) has been shown to improve IR and is associated with a lower risk of hypoglycemia onset in T1DM compared to aerobic exercise. Additionally, the molecular mechanisms mediating RT-induced improvements in insulin sensitivity remain unclear. Therefore, the purpose of this study was to investigate the effects of RT on IR development in female …

Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii

Doctoral Dissertations

Muscle size does not fully explain variations in muscle strength. Fat content has been implicated in muscle weakness, though this relationship remains unclear. The relationship between fat and strength may vary between scales (e.g., cellular, organ, and organism). The goal of this dissertation was to clarify the role of fat in the structure and function of muscle using in vitro and in vivo techniques across multiple scales in adults 21-45 years old. Study 1 tested the agreement of intramyocellular lipid (IMCL) content between oil red o (ORO) and magnetic resonance spectroscopy (MRS) techniques. These measures of IMCL were also compared …

The Sympathetic Neural Control Of The Circulation At Rest And During Exercise: Effects Of Age, Biological Sex, And Sex Hormones, Andrew W. D'Souza

Electronic Thesis and Dissertation Repository

The overall objective of this dissertation was to determine the impact of age, sex, and sex hormones on the discharge behaviours of muscle sympathetic action potentials (APs) as well as the corresponding changes in peripheral vasoconstriction and blood pressure at rest and during exercise. The microneurographic technique was employed to record multi-unit muscle sympathetic nerve activity (MSNA), with a continuous wavelet transform applied post-hoc to evaluate APs within the recorded neurogram. Study One examined the impact of aging on the central and peripheral arcs of the sympathetic baroreflex under resting conditions. This study revealed that middle-aged-to-older adults demonstrated heightened sympathetic …

Does Acute Maximal Exercise Or Chronic Physical Activity Affect Circulating Angiotensin (1-9) Concentrations?, Kyle R. Weiman

Electronic Thesis and Dissertation Repository

Introduction: Epidemiological evidence suggests physical inactivity can increase the likelihood of hospitalization from the SARS-COV-2 virus. Further, some data indicate a greater ratio of angiotensin 1-9 to angiotensin I helps prevent severe outcomes during infection. Moreover, related hormones can enhance potentially both physical activity and health. The purpose of this study was to determine whether plasma concentrations of angiotensin (1-9) are modified after a single exhaustive exercise bout and whether sex or chronic physical activity is associated with greater plasma concentrations.

Methods: Participants (n=14) performed a graded exercise test on a cycle ergometer. Antecubital area venipunctures were performed before, immediately …

Resistance Training And Running Performance And Economy: A Literature Review, James Bottrill

University Honors Theses

Running performance is largely determined by maximal oxygen uptake (VO₂ max), velocity at VO₂ max, fractional utilisation of VO₂ max and running economy. Running economy is relatively under-researched and could be improved by resistance training because of its neuromuscular underpinnings. However, existing research on this topic is quite unorganised and inconclusive and is yet to prove a direct linkage between resistance training, running economy and performance. This literature review aimed to provide an organised overview of the existing literature, identify and address confounding variables and provide recommendations for future research. A search for studies was conducted via …

Comparing Calculated And Perceived Energy Needs In Collegiate Student-Athletes, Lyndsey T. Reed

Honors Theses

The purpose of this study was to evaluate NCAA student-athletes' level of knowledge related to their energy needs. The participants were 75—42 male and 33 female—NCAA Division I student-athletes enrolled at the University of Mississippi (UM) from a variety of sports. In-person data collection took place at UM Athletics facilities by sports registered dietitians during team talks. The names of the athletes were used to find their pre-existing calculated energy, resting metabolic rate (RMR) and total energy expenditure (TEE) using the Nelson equation and the appropriate activity factor. Questionnaire and RMR/TEE data were analyzed and compared to assess knowledge related …

The Effects Of Acute Exercise On Memory: Considerations Of The Testing Effect, Philip Christian

Honors Theses

This study had three main objectives. The first objective was to determine whether or not there was evidence of a testing effect being present when a short-term memory assessment is included along with a long-term memory assessment. The second objective was to determine whether acute exercise can improve long-term memory recall over a control condition. The third objective was to determine if the potential effects of acute exercise on long-term memory are confounded by the inclusion of a short-term memory assessment. Participants were 54 undergraduate students at the University of Mississippi, with an age range of 18-22 years old. Participants …

Transcutaneous Electrical Stimulation Does Not Decrease Torque Loss Over High Intensity Repetitions, Ian Koskinen

All NMU Master's Theses

Transcutaneous Electrical Stimulation, TENS, has been used widely as an analgesic and ergogenic aid for many years. Compared to other modalities of electrical stimulation, TENS has been shown to provide some benefits in exercise performance by reducing pain and increasing endurance in low intensity applications, such as time trial cycling or isometric endurance. While TENS has been shown to have a significant effect on exercise induced pain in individuals performing endurance activities, to my knowledge it has not been examined in high intensity contractions. 18 active young adults (age: 23.11 years ± 2.08, resistance training experience: 7.08 years ± 3.79, …

Beyond The Fat: Protein Metabolism And Muscle Function As Part Of The Migratory Syndrome Of Songbirds, Cory R. Elowe

Doctoral Dissertations

Migration allows animals to seasonally exploit favorable habitats that are geographically disparate, and migratory animals have a suite of adaptations to complete their extraordinary journeys. This “migratory syndrome” of traits is comprised of seasonally-responsive adaptations that together result in changes to metabolism, body composition, and reproductive status, all of which act to increase the probability of a successful migration. The focus of my dissertation is to investigate the suite of changes in metabolism and muscle function that enable birds to undertake long-duration flights. In chapter 1, I compare fuel use in flight between two related migratory warbler species that migrate …

Sit Less, Move More: A National Study Of Physical-Activity Behavior And Cancer, Stella O. Nwogugu

Dissertations, Theses, and Capstone Projects

Background: Physical activity is associated with lower risks of cancer, the second leading cause of death among Americans. Yet, sedentary behavior is the prevailing lifestyle for about 80% of American adults. Additionally, cancer survivors remain significantly inactive, even though physical activity has been shown to decrease risk of cancer and cancer recurrence, improve tolerance of cancer therapy, and reduce mortality. This research explores the relative impact of personal agency, social support, and key demographic variables on physical-activity behavior for a national sample of adults as well as how these relationships differ for cancer survivors and their counterparts.

Methods: Using the …

Enhancing The Quality Of Life For Senior Citizens: A Facilitator’S Guidebook For Mindful Music And Movement, Shannon Sexton

Mindfulness Studies Theses

Music appreciation and enjoyment enhance well-being throughout the lifespan. The challenges and constraints that people experience as they age can lead to lack of access to music, decreased physical activity, and fewer avenues for creative expression. Group music and movement interventions created for older populations offer opportunities for social connection and improved quality of life. Mindful practices add further benefit when combined with these interventions. Current available programs are scarce and most often do not encompass mixed modalities. In addition, the benefits of these programs do not show long-term sustainability. The purpose of this thesis is to explore the effects …

Association Between Baseline Field Test Performance And Match Physical Performance In D1 Female Soccer Players, Benito Joel Cecenas

Graduate Student Theses, Dissertations, & Professional Papers

Background: Fitness testing is utilized by numerous soccer programs as a means for evaluation of player physical capacity. Previous literature has shown Yo-Yo Intermittent Recovery Test Level 1 (YYIR1) performance is associated with match physical performance in elite adult and youth soccer players. Until now, these relationships have not been investigated in the collegiate soccer setting, despite the YYIR1 being regularly utilized at the collegiate level to determine eligibility for competition, influence playing time, and to assess adaptation to training programs. For these reasons the association between the YYIR1 and match physical performance was investigated in women’s collegiate soccer.

Aims: …

Longitudinal Sport Science Implementation In American Collegiate Men’S Basketball, Jason Stone

Graduate Theses, Dissertations, and Problem Reports

The expanding opportunities to implement sport science frameworks in elite-level basketball environments coincide with the sport’s increasing global prominence. Concomitant to these opportunities is the continual growth of the sport technology market (e.g., wearables, force plates) and computational power (e.g., data management tools, coding capabilities), which yields solutions and challenges for both athletes and practitioners. Due to the rapid influx of new sport technologies in high performance environments, particularly American Collegiate Men’s Basketball, more formal and ecologically valid research on how to effectively utilize data derived from them, particularly over long periods of time (i.e., multiple seasons) is needed. To …

A Comparison Of Barriers To Traditional And Home-Based Cardiopulmonary Rehabilitation Participation: Potential Implications For The Maintenance Phase, Erin Rose Madison

Graduate Student Theses, Dissertations, & Professional Papers

Cardiac rehabilitation provides medically supervised therapeutic exercise and multifaceted risk factor modification as a form of secondary prevention for cardiovascular disease, a persistent leading cause of morbidity and mortality in the United States and internationally. Despite robust evidence of compelling patient outcomes, decreased disease recurrence, and the indications from the ACC/AHA endorsing phase II cardiac rehabilitation (CR) as a crucial aspect of recovery from cardiac events and qualifying conditions, CR is widely underutilized. A variety of patient barriers can serve as mitigating factors to CR referral, enrollment, participation, and completion contributing to, in part, the underutilization of CR. Barriers to …

Return-To-The-Platform: The Case Of A Collegiate Level Weightlifter Recovering From A Meniscus Injury, Nicholas Harden

Electronic Theses and Dissertations

The purpose of this study was to observe physiological metrics relative to training-induced adaptations in conjunction with laboratory- and competition-based performances in a super-heavyweight weightlifter recovering from a meniscus injury. A retrospective analysis was conducted on a collegiate level male weightlifter (23.2 yrs; 131.9 kg; 187.3 cm) over the course of 21-weeks post-meniscus surgery. Body mass, body fat percentage, hydration status, vastus lateralis muscle cross-sectional area, jump performance, and isometric midthigh pull were regularly assessed as part of an ongoing athlete monitoring program. Pre-injury baseline (T0) measurements were collected relative to a major national competition (COMP1). Post-injury measurements took place …

Voltage-Gated Potassium Channel Dependent Mechanisms Of Cardiovascular Adaptation To Chronic Exercise., Sean Raph

Electronic Theses and Dissertations

Exercise increases cardiac workload, escalating the demand for oxygen. The myocardial vasculature responds to the greater demand for oxygen by increasing blood flow to match the needs of the heart during augmented work. Increasing blood flow requires the coronary arteries dilate (a.k.a. vasodilation); this is mediated predominantly by vascular smooth muscle cell relaxation. Vasodilation is driven through inhibition of calcium influx into vascular smooth muscle cells. The prevention of calcium influx is largely mediated by efflux of potassium via potassium channels causing membrane hyperpolarization, which in turn closes voltage-dependent (or gated) calcium channels (VDCC). Changes in vascular smooth muscle cell …

Metabolic Foundations Of Exercise-Induced Cardiac Growth., Kyle Fulghum

Electronic Theses and Dissertations

Regular aerobic exercise promotes physiological cardiac growth, which is an adaptive response thought to enable the heart to meet higher physical demands. Cardiac growth involves coordination of catabolic and anabolic activities to support ATP generation, macromolecule biosynthesis, and myocyte hypertrophy. Although previous studies suggest that exercise-induced reductions in cardiac glycolysis are critical for physiological myocyte hypertrophy, it remains unclear how exercise influences the many interlinked pathways of metabolism that support adaptive remodeling of the heart. In this thesis project, we tested the general hypothesis that aerobic exercise promotes physiological cardiac growth by coordinating myocardial metabolism to promote glucose-supported anabolic pathway …

Unraveling The Effects Of Aerobic Exercise And Erk5 Signaling In The Solid Tumor Microenvironment Using Murine Models, Hannah Savage

Dissertations & Theses (Open Access)

Solid tumors are comprised of multiple cell types which communicate and work together to promote tumor progression. Advances in the treatment of solid tumors have armed clinicians with more efficacious pharmacologic agents and combinations. However, a focus on drug adjuvants in the treatment of solid cancer has left gaps in knowledge regarding non-pharmacologic treatment adjuvants, like aerobic exercise. The current dissertation investigates pharmacologic and non-pharmacologic based approaches to remodel the solid tumor microenvironment landscape and alter therapeutic efficacy. We disassemble compartments of the tumor microenvironment, including tumor vasculature and immune infiltrate, using mouse models and single cell techniques, to elucidate …

Heat Stress And The Control Of Skeletal Muscle Mass, Zachary J. Fennel

Health, Exercise, and Sports Sciences ETDs

PURPOSE: 1) Compare the effects of whole-body heat stress (HS) and resistance exercise (RE) on thermoregulatory responses and skeletal muscle heat shock and hypertrophy related signaling. 2) Examine the effects of acute heat stress (HEAT) on myotube growth and fusion compared to controls (CON), hypertrophy (HYPER), and atrophy (RAPA) treatments in-vitro. METHODS: 1) Eight healthy, physically active and resistance trained individuals (18-45 years) completed RE and HS. 2) 48 hours following treatments, C2C12 myotubes were assessed for myotube area and nuclear fusion index. RESULTS: 1) RE and HS similarly increased muscle but not core temperatures. HS but not RE increased …

The Effect Of Breathing Patterns Common To Competitive Swimming On Gas Exchange And Muscle Deoxygenation During Heavy-Intensity Fartlek Exercise, Kevin J. Grossman

Electronic Thesis and Dissertation Repository

The purpose of this study was to compare the respiratory and muscle deoxygenation (HHb) responses of regulated breathing versus free-breathing, during continuous exercise (CONLD) and intermittent 5s breath holds (BH) (CONLD-BH), intermittent 5s sprint (FLK) and combined 5s BH and sprint (FLK-BH) followed by 25s of free-breathing. Oxygen uptake(V̇O₂)was unchanged between CONLD (2.12±0.35L/min) and CONLD-BH (2.15±0.42L/min; p=0.116), and FLK (2.24±0.40L/min) and FLK-BH (2.20±0.45L/min; p=0.861). Δ[Hb_tot]: CONLD (3.3±1.6µM) > CONLD-BH (-2.5±1.2µM; ∆177%; p<0.001), but unchanged between FLK (2.0±1.6µM) and FLK-BH (0.82±1.4µM; p=0.979). Δ[HHb]: CONLD (7.3±1.8µM) > CONLD-BH (7.0±2.0µM; ∆4%; p=0.011), and FLK (6.7±1.8µM) < FLK-BH (8.7±2.4µM; p<0.001). It is suggested that the unchanged V̇O₂ between CONLD and CONLD-BH was supported by increased deoxygenation, reflected by decreased ∆[Hb_tot] and blunted …

The Effect Of Covid-19 On Exercise Performance, Elizabeth Crockett

Undergraduate Theses and Capstone Projects

The purpose of this study was to determine if a history of COVID-19 affects exertion rates during exercise. 16 subjects (8 with a history of COVID-19 and 8 without) completed the Ebbeling Submaximal Treadmill Test during which ratings of perceived exertion (RPE), heart rate, blood pressure, breath rate, and estimated VO2max were assessed. Previous physical activity habits and exercise participation were assessed prior to the exercise test. Following exercise, subjects were asked to compare exertion levels during the treadmill test to previous exertion levels prior to COVID-19 infection. We found that those with a history of COVID-19 may experience a …

The Effects Of Carbonyl Iron Vs Ferrous Sulfate On Blood Iron Markers In Male Division Iii Cross-Country Athletes, Sam Gunter

Undergraduate Theses and Capstone Projects

Competitive distance runners are often predisposed to developing iron deficiency. This study aimed to determine if carbonyl iron was more effective at maintaining blood iron markers and minimizing overall fatigue and GI stress than ferrous sulfate. In this randomized, independent groups study, 7 male, division III cross-country athletes were supplemented with either carbonyl iron or ferrous sulfate for 6 weeks. Blood hemoglobin, hematocrit, subjective GI distress, subjective fatigue, and relative exertion of recent training were assessed at baseline, 3 and 6 weeks. Results were analyzed via one -way and repeated measures analyses of variance (ANOVA) to determine significant differences in …