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Full-Text Articles in Physiology
The Long Haul: Migratory Flight Preparation And Performance In Songbirds, Morag F. Dick
The Long Haul: Migratory Flight Preparation And Performance In Songbirds, Morag F. Dick
Electronic Thesis and Dissertation Repository
Migration requires birds to sustain high intensity endurance exercise for periods lasting from hours to days. Similar to athletes, preparation and nutrition is key to success. Birds seasonally prepare for migration, which includes increasing the capacity to oxidize fat in the flight muscles. Beyond fuelling migration, n-3 long-chain polyunsaturated fatty acids (PUFA) are hypothesized to be natural doping agents and increase endurance and fatty acid oxidative capacity. I examined how birds prepare for and sustain migratory flight and directly tested the role of n-3 PUFA. Using yellow-rumped warblers (Setophaga coronata) as a model species, I first examined the …
On The Origin Of Superoxide Dismutase: An Evolutionary Perspective Of Superoxide-Mediated Redox Signaling., Adam J. Case
On The Origin Of Superoxide Dismutase: An Evolutionary Perspective Of Superoxide-Mediated Redox Signaling., Adam J. Case
Journal Articles: Cellular & Integrative Physiology
The field of free radical biology originated with the discovery of superoxide dismutase (SOD) in 1969. Over the last 5 decades, a plethora of research has been performed in species ranging from bacteria to mammals that has elucidated the molecular reaction, subcellular location, and specific isoforms of SOD. However, while humans have only begun to study this class of enzymes over the past 50 years, it has been estimated that these enzymes have existed for billions of years, and may be some of the original enzymes found in primitive life. As life evolved over this expanse of time, these enzymes …