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Full-Text Articles in Physiology
Ca2+ Entry Units In A Superfast Fish Muscle, James Matthew Kittelberger, Clara Franzini-Armstrong, Simona Boncompagni
Ca2+ Entry Units In A Superfast Fish Muscle, James Matthew Kittelberger, Clara Franzini-Armstrong, Simona Boncompagni
Biology Faculty Publications
Over the past two decades, mounting evidence has demonstrated that a mechanism known as store-operated Ca2+ entry (SOCE) plays a crucial role in sustaining skeletal muscle contractility by facilitating Ca2+ influx from the extracellular space during sarcoplasmic reticulum (SR) Ca2+ depletion. We recently demonstrated that, in exercised fast-twitch muscle from mice, the incidence of Ca2+ entry units (CEUs), newly described intracellular junctions between dead-end longitudinal transverse tubular (T-tubule) extensions and stacks of sarcoplasmic reticulum (SR) flat cisternae, strictly correlate with both the capability of fibers to maintain contractions during fatigue and enhanced Ca2+ influx via SOCE. Here, we tested the …
Navigating The “Covid Hangover” In Physiology Courses, Jennifer E. Schaefer
Navigating The “Covid Hangover” In Physiology Courses, Jennifer E. Schaefer
Biology Faculty Publications
Undergraduate educators and students must navigate lingering aftereffects of the COVID pandemic on education in the 2021–2022 academic year even as COVID continues to impact delivery of undergraduate science education. This article describes ongoing difficulties for undergraduate science, technology, engineering, and mathematics (STEM) students and educators and suggests strategies and easy-to-use resources that may help educators navigate the “COVID hangover” and ongoing COVID-related disruptions.