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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Low Dose Nerve Agent Sarin Causes Dilated Cardiomyopathy And Autonomic Imbalance In Mice, Swapnil Vijay Shewale Jan 2011

Low Dose Nerve Agent Sarin Causes Dilated Cardiomyopathy And Autonomic Imbalance In Mice, Swapnil Vijay Shewale

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Sarin, a lethal chemical nerve agent, may be a causative factor in multifactorial syndrome implicated in the Gulf War and Tokyo terrorist attacks. While high dose results in seizure and death, low dose exposure may lead to autonomic imbalance and chronic cardiac pathologies. In the present study, echocardiography and electrocardiography were used to examine the late onset effects of a low dose sarin on cardiac structure and function in mice. Stress responsiveness of the hypothalamic pituitary adrenal (HPA) axis was also tested. Findings demonstrate changes consistent with a dilated cardiomyopathy, including left ventricular dilatation, reduced contractility, and altered electrophysiological and …


Effects Of Dietary Supplementation Of The Acidifier Vitoxal-Mionix On Growth, Survival, Immune Response And Gut Microbiota Of The Pacific White Shrimp, Litopenaeus Vannamei, Ahmed Mustafa, Davies Anuta, Alehandro Buentello, Susmita Patnaik, Addison Lawrence, Michaele Hume, Delbert Gatlin, Maurice Kemp Dec 2010

Effects Of Dietary Supplementation Of The Acidifier Vitoxal-Mionix On Growth, Survival, Immune Response And Gut Microbiota Of The Pacific White Shrimp, Litopenaeus Vannamei, Ahmed Mustafa, Davies Anuta, Alehandro Buentello, Susmita Patnaik, Addison Lawrence, Michaele Hume, Delbert Gatlin, Maurice Kemp

Ahmed Mustafa Dr.

No abstract provided.


Feasibility Of Farming Nile Tilapia, Oreochromis Niloticus (L.), In Suboptimal Water Temperature, Ahmed Mustafa, Laura Randolph, Shree Dhawale Dec 2010

Feasibility Of Farming Nile Tilapia, Oreochromis Niloticus (L.), In Suboptimal Water Temperature, Ahmed Mustafa, Laura Randolph, Shree Dhawale

Ahmed Mustafa Dr.

No abstract provided.


Effects Of Indian Herbs On The Modulation Of Stress And Immune Response In Tilapia, Ahmed Mustafa, Brittany Byerley, Paul Mccain Dec 2010

Effects Of Indian Herbs On The Modulation Of Stress And Immune Response In Tilapia, Ahmed Mustafa, Brittany Byerley, Paul Mccain

Ahmed Mustafa Dr.

No abstract provided.