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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Investigating The Antiviral Effects Of Vig-3 From Rainbow Trout, Shanee Herrington-Krause
Investigating The Antiviral Effects Of Vig-3 From Rainbow Trout, Shanee Herrington-Krause
Theses and Dissertations (Comprehensive)
Rainbow trout is the most farmed fish in Ontario, and thus is economically important to the province. Despite this, there is a lack of understanding regarding fish innate immunity, specifically with regards to interferon-stimulated genes (ISGs) and their antiviral effector functions. ISGs are the workhorses of the innate antiviral response, operating together to limit each step of virus replication. The Viral Hemorrhagic Septicemia Virus (VHSV) induced gene (Vig)-3 is a newly identified ISG within many fish species and is homologous to ISG-15 in mammals. It is a small ubiquitin-like protein inducible by type I interferon (IFN-I), and is suggested to …
Potential Impact Of Northern Resource Development On Aquatic Biota: Toxicity Of Chromium And Rare Earth Element Processing Reagent, So Yeon Choi
Theses and Dissertations (Comprehensive)
Chromite and rare earth element development was identified in the 2015 Canadian Federal budget as a significant opportunity, however, key data gaps exist regarding the environmental concerns related to these resource developments. Chromium is essential in the production of stainless steel, and no suitable substitute is known. Rare earth elements (REEs) are a series of metals that are composed of 15 lanthanides, as well as scandium and yttrium. Uses for REEs range from electronic devices (i.e. cell phones, computers, televisions) to magnets and controlling nuclear reactors. While commercial production of REEs signify a great economic opportunity for Canada, key data …