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Pharmacology, Toxicology and Environmental Health Commons

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Journal

2010

Discipline
Institution
Keyword
Publication

Articles 1 - 18 of 18

Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Exhausted Or Unlicensed: Can Field-Of-Use Restrictions In Biotech License Agreements Still Prevent Off-Label Use Promotion After Quanta Computer?, Kristal M. Wicks Dec 2010

Exhausted Or Unlicensed: Can Field-Of-Use Restrictions In Biotech License Agreements Still Prevent Off-Label Use Promotion After Quanta Computer?, Kristal M. Wicks

The University of New Hampshire Law Review

[Excerpt] “In the biotechnology (biotech) industry, companies must be increasingly aware of their intellectual property and how their licensing strategies can impact their rights. When licensing patented technology, it is common practice for biotech companies to include restricted field-of-use provisions in their license agreements. Such provisions permit a licensee to only use licensed technology in a defined field and restrict use or development in another field. This licensing strategy plays an important role within the biotech industry because it allows companies to more effectively control their intellectual property and to more efficiently research and develop pharmaceutical products.

A problem that …


Role Stress, Emotional Exhaustion, And Job Satisfaction In The Hotel Industry: The Moderating Role Of Supervisory Support, Osman M. Karatepe Jan 2010

Role Stress, Emotional Exhaustion, And Job Satisfaction In The Hotel Industry: The Moderating Role Of Supervisory Support, Osman M. Karatepe

Hospitality Review

The purpose of this study is to investigate supervisory support as a moderator of the effects of role conflict and role ambiguity on emotional exhaustion and job satisfaction. This study also examines the moderating role of supervisory support on the relationship between emotional exhaustion and job satisfaction. Data were collected from a sample of frontline hotel employees in Northern Cyprus. The aforementioned relationships were tested based on hierarchical multiple regression analysis. The results demonstrate that supervisory support mitigates the impact of role conflict on emotional exhaustion and further reveal that supervisory support reduces the effect of emotional exhaustion on job …


Micelle Enhanced Spectrofluorimetric Method For The Determination Of Ofloxacin And Lomefloxacin In Human Urine And Serum, Kuldeep Kaur, Baldev Singh, Ashok Kumar Malik Jan 2010

Micelle Enhanced Spectrofluorimetric Method For The Determination Of Ofloxacin And Lomefloxacin In Human Urine And Serum, Kuldeep Kaur, Baldev Singh, Ashok Kumar Malik

The Thai Journal of Pharmaceutical Sciences

A spectrofluorimetric method for the determination of two fluoroquinolone drugs, ofloxacin and lomefloxacin in biological fluids has been developed. The method is based on native fluorescence of these drugs in micellar medium of sodium dodecyl sulfate (S...


Studies On Formulation Development Of Apoorly Water - Soluble Drug Through Solid Dispersion Technique, Sunita Dahiya Jan 2010

Studies On Formulation Development Of Apoorly Water - Soluble Drug Through Solid Dispersion Technique, Sunita Dahiya

The Thai Journal of Pharmaceutical Sciences

An attempt has been made to enhance dissolution of aceclofenac (AC) by solid dispersion technique using water soluble carriers PEG 6000 and β-cyclodextrin (β-CD). Solid dispersions of AC with PEG 6000 were prepared by melting solvent method and with β...


Use Of Charge Transfer Complexation Reaction For The Spectrophotometric Determination Of Bupropion In Pharmaceuticals And Spiked Human Urine, Kanakapura Basavaiah, Sameer A. M. Jan 2010

Use Of Charge Transfer Complexation Reaction For The Spectrophotometric Determination Of Bupropion In Pharmaceuticals And Spiked Human Urine, Kanakapura Basavaiah, Sameer A. M.

The Thai Journal of Pharmaceutical Sciences

This is the first report on use of two visible spectrophotometric methods for the determination of bupropion hydrochloride (BUPH) in pharmaceuticals and spiked human urine. Bupropion is a second-generation antidepressant agent which is also used in the m...


Simultaneous Spectrophotometric Determination Of Iron (Ii) And Copper (Ii) In Tablets By Chemometric Methods, Melisew Tadele Alula, Abdel-Maaboud I., Adnan A. Bekhit Jan 2010

Simultaneous Spectrophotometric Determination Of Iron (Ii) And Copper (Ii) In Tablets By Chemometric Methods, Melisew Tadele Alula, Abdel-Maaboud I., Adnan A. Bekhit

The Thai Journal of Pharmaceutical Sciences

The significant spectral overlap (Di)0.5 = 0.5667 which is about 75.3% overlapping of the UV/Visible absorption spectra of iron (II) and copper (II) complexes necessitates chemometric assisted methods for simultaneous analysis of these ions in the pharma...


Anticonvulsant Activity Of Methanolic Extract Of Clerodendron Infortunatum Linn, In Swiss Albino Mice, Sudipta Das, Pallab K., Goutam Pramanik, Siva P. Panda, Samit Bera Jan 2010

Anticonvulsant Activity Of Methanolic Extract Of Clerodendron Infortunatum Linn, In Swiss Albino Mice, Sudipta Das, Pallab K., Goutam Pramanik, Siva P. Panda, Samit Bera

The Thai Journal of Pharmaceutical Sciences

The present study was designed to investigate the anticonvulsant and sleep potentiation effect of methanolic extract of C lerodendron info rtun atum Linn. (MECI) leaves in Swiss albino mice. The anticonvulsant effect of the MECI (250, 500 mg/kg body weig...


Sensitive Ultraviolet Spectrophotometric Determination Of Quetiapine Fumarate In Pharmaceuticals, K. Basavaiah, N. Rajendraprasad, P.J. Ramesh, K.B. Vinay Jan 2010

Sensitive Ultraviolet Spectrophotometric Determination Of Quetiapine Fumarate In Pharmaceuticals, K. Basavaiah, N. Rajendraprasad, P.J. Ramesh, K.B. Vinay

The Thai Journal of Pharmaceutical Sciences

Quetiapine fumarate (QTF) is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives indicated for the treatment of schizophrenia. It is a selective monoaminergic antagonist with high affinity for the serotonin type 2 (5HT2), an...


Conjugation Of Some Nsaids With 5-Phenyl-2-Aminothiazole For Reduced Ulcerogenicity, Abhilasha Verma, Nirupam Das, Meenakshi Dhanawat, Sushant K. Shrivastava Jan 2010

Conjugation Of Some Nsaids With 5-Phenyl-2-Aminothiazole For Reduced Ulcerogenicity, Abhilasha Verma, Nirupam Das, Meenakshi Dhanawat, Sushant K. Shrivastava

The Thai Journal of Pharmaceutical Sciences

Analgesic drugs containing free acidic group were reacted with N, N' carbonyldiimidazole to prepare the acylimidazole derivatives. They were further reacted with 5-phenyl-2-amino thiazole nucleus to obtain the corresponding amides. All the compounds were...


Comparative Study Of Extraction, Purification And Estimation Of Bromelain From Stem And Fruit Of Pineapple Plant, S. S. Gautam, S. K., V. Dash, Amit K. Goyal, G. Rath Jan 2010

Comparative Study Of Extraction, Purification And Estimation Of Bromelain From Stem And Fruit Of Pineapple Plant, S. S. Gautam, S. K., V. Dash, Amit K. Goyal, G. Rath

The Thai Journal of Pharmaceutical Sciences

Bromelain is a major proteinase, isolated from pineapple (Ananas comosus). In the plant, bromelain is accumulated in the entire plant to different extent and properties depending on its source. The objective of present study was to compare the amount and...


Patients’ Opinion And Practice Toward Unused Medication Disposal In Malaysia : A Qualitative Study, Redhwan Ahmed Al-Naggar, Adel Alareefi Jan 2010

Patients’ Opinion And Practice Toward Unused Medication Disposal In Malaysia : A Qualitative Study, Redhwan Ahmed Al-Naggar, Adel Alareefi

The Thai Journal of Pharmaceutical Sciences

This study was conducted to explore the opinion and practice toward disposal of unused medication among patients in Malaysia. An in-depth interview conducted during the period from December 2009 until February 2010. A total of 28 patients participated in...


Improvement In The Dissolution Of Poorly Water Soluble Drug Using Media Milling Technique, Dhaval J. Patel, Jayvadan K., Vikram M. Pandya Jan 2010

Improvement In The Dissolution Of Poorly Water Soluble Drug Using Media Milling Technique, Dhaval J. Patel, Jayvadan K., Vikram M. Pandya

The Thai Journal of Pharmaceutical Sciences

The rate of dissolution is rapidly becoming the leading hurdle in formulation development of poorly water-soluble drugs. In the present work, media milling was employed to formulate nanoparticles of a poorly water-soluble anti-ulcer drug, famotidine (FAM...


Author Index, Keyword Index, N/A Jan 2010

Author Index, Keyword Index, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Antitumour Activities Of Some Schiff Bases Derived From Benzoin, Salicylaldéhyde, Amino Phenol And 2,4 Dinitrophenyl Hydrazine, M. Jesmin, M.M. Ali, J.A. Khanam Jan 2010

Antitumour Activities Of Some Schiff Bases Derived From Benzoin, Salicylaldéhyde, Amino Phenol And 2,4 Dinitrophenyl Hydrazine, M. Jesmin, M.M. Ali, J.A. Khanam

The Thai Journal of Pharmaceutical Sciences

Three schiff bases PDH [N-(1-phenyl-2-hydroxy-2phenyl ethyledine)-2', 4' dinitrophenyl hydrazine], PHP [N-(1 -phenyl, 2-hydroxy-2-phenyl ethylidine)-2' hydroxy phenyl imine] and HHP [N-(2-hydroxy benzylidine)-2' hydroxy phenyl imine] have been studied ag...


Antioxidant And Neuroprotective Effects Of Standardized Extracts Of Mangifera Indica Leaf, Kanistha Kawpoomhae, Monrudee Sukma, Tanasait Ngawhirunpat, Praneet Opanasopit, Areerut Sripattanaporn Jan 2010

Antioxidant And Neuroprotective Effects Of Standardized Extracts Of Mangifera Indica Leaf, Kanistha Kawpoomhae, Monrudee Sukma, Tanasait Ngawhirunpat, Praneet Opanasopit, Areerut Sripattanaporn

The Thai Journal of Pharmaceutical Sciences

Standardized methanol and aqueous extracts of Mangifera indica L. (mango) leaf were analyzed for antioxidant and neuroprotective activities. Antioxidant activities were evaluated by 2, 2-azinobis 3-ethylbenzothiazoline 6-sulfonate (ABTS), 1,1-diphenyl-2-...


Inhibitory Effect Of 2,5-Bis(4-Hydroxy-3-Methoxybenzylidene) Cyclopentanone On Mast Cell Histamine Mediated-Rat Paw Edema, Agung Endro Nugroho, Sardjiman, Kazutaka Maeyama Jan 2010

Inhibitory Effect Of 2,5-Bis(4-Hydroxy-3-Methoxybenzylidene) Cyclopentanone On Mast Cell Histamine Mediated-Rat Paw Edema, Agung Endro Nugroho, Sardjiman, Kazutaka Maeyama

The Thai Journal of Pharmaceutical Sciences

2,5-Bis(4-hydroxy-3-methoxybenzylidene)cyclopentanone, known as pentagamavunon-0 (PGV-0), is a benzylidene cyclopentanone analog of curcumin. This compound posses stronger pharmacological activities such as anti-inflammatory, antioxidative and antibacter...


Full Issue: Volume 3, Number 1 Jan 2010

Full Issue: Volume 3, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.


Full Issue: Volume 4, Number 1 Jan 2010

Full Issue: Volume 4, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.