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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Toxicity Of Tolyltriazole To Bacillus Microorganisms, Christopher J. Leonard
Toxicity Of Tolyltriazole To Bacillus Microorganisms, Christopher J. Leonard
Theses and Dissertations
The safety of air travel in cold weather depends upon the use of aircraft deicing fluids (ADAF). The environmental and toxic effects of the ADAF component tolyltriazole are not well understood. Tolyltriazole is a potential human carcinogen and has exhibited microbial toxicity in Microtox test. This research used two methods to investigate the toxicity of tolyltriazole on bacillus shaped microorganisms. The first method compared the dissolved oxygen uptake of microcosms exposed to varying concentrations of tolyltriazole. When exposed to 1000 ppm tolyltriazole, all isolated species showed inhibition in respiration. There was no evidence that tolyltriazole at
Chromate Dissociation From Primer Paint In Simulated Lung Fluid, Tiffany J. R. Morgan
Chromate Dissociation From Primer Paint In Simulated Lung Fluid, Tiffany J. R. Morgan
Theses and Dissertations
OSHA has proposed a new strontium chromate exposure standard that would potentially cause Air Force paint facilities to be in violation of the proposed standard if adopted. This proposed reduction make the continued use of chromate containing primer paints very difficult. There is currently no acceptable replacements for chromate containing primer paints on AF aircraft. This study suggests that paint particles with chromate bound in primer paint may be unavailable for bodily absorption if inhaled and a reduced standard for painting applications may be unnecessary. Primer paint overspray was collected into simulated lung fluid (SLF) and allowed 6 hr, 24 …
A Pharmacokinetic Study Of The Effects Of Stress On Chemical Exposure, Sierra H. Suhajda
A Pharmacokinetic Study Of The Effects Of Stress On Chemical Exposure, Sierra H. Suhajda
Theses and Dissertations
Following the Gulf War there were many concerns raised about human exposure to the combination of chemicals and stress. Stress causes several changes in basic functions of a human body, from breathing and blood flow changes to hormonal and enzyme changes, and increased permeability of the blood-brain barrier. Each of these changes can strongly influence chemical uptake, distribution, and accumulation in the body. The purpose of this thesis was to model and predict the changes that will occur when stress is combined with chemical exposure. Physiologically-based pharmacokinetic (PBPK) modeling is one tool that can be used to visualize, predict, and …