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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Opioids Disrupt Sleep And Wakefulness In C57bl/6j Mice, Clarence E. Locklear
Opioids Disrupt Sleep And Wakefulness In C57bl/6j Mice, Clarence E. Locklear
Masters Theses
Opioid use disorder (OUD) is a major public health burden. According to the National Institutes of Health (NIH), studies helping to understand the mechanisms of OUD will help improve prevention and treatment. Opioids long have been shown to disrupt sleep and sleep disruption enhances the likelihood of addiction relapse in humans. The NIH refers to the mouse as one of the most powerful animal systems to study because of the genetic homologies between human and mouse. Prior to the present research, no studies have quantified the effect of opioids on states of sleep and wakefulness in mice. The current study …
Seasonal Temperature Changes In Three Midwestern Wastewater Streams And The Effects On Fish Assemblages And Physiology, Ryan William Sparks
Seasonal Temperature Changes In Three Midwestern Wastewater Streams And The Effects On Fish Assemblages And Physiology, Ryan William Sparks
Masters Theses
Midwestern United States undergo extreme temperature and precipitation fluctuations throughout the year, which leads to changing habitats within Illinois river systems. Wastewater treatment facilities have long been used to treat sewage and reduce the organic products in sewage before releasing it into aquatic environments. Wastewater treatment facilities must maintain optimal conditions, especially temperature, for reproduction and growth of facilitated bacteria that break down organic materials in wastewater. The objectives for this study were to determine the thermal effects of wastewater treatment facilities on receiving waters; and secondly, to investigate the influence of these wastewater facilities on fish abundance and assemblages. …