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Articles 1 - 5 of 5
Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Human Health And Environmental Hazards Of Farmed Fish, Richard B. Philp
Human Health And Environmental Hazards Of Farmed Fish, Richard B. Philp
Richard B. Philp
Aquaculture, or fish farming, now provides a significant portion of the world's supply of fin-fish for human consumption. Since 1985, the production of farmed fish has nearly quadrupled. Associated problems include levels of persistent organic pollutants and heavy metals as compared to wild-caught fish, enviromnental problems from waste food and excrement, disease hazards for fish and humans and depletion of wild forage fish to produce food pellets for farmed fish. The recent introduction of genetically modified salmon has added another potential hazard for the environment and possible for human health. These and other problems are discussed with recommendations for human …
Predictors Of Safety-Related Enquiries About Psychotropic Medication In Young People And Families Accessing A Medicines Information Service, Angela Dean, Merryn Witham, Treasure Mcguire
Predictors Of Safety-Related Enquiries About Psychotropic Medication In Young People And Families Accessing A Medicines Information Service, Angela Dean, Merryn Witham, Treasure Mcguire
Treasure McGuire
Background: Many consumers express concerns about the safety of psychotropic medication for young people. Despite the increased use of psychotropic medication in children and adolescents, few studies have examined information needs of this group and predictors of safety-related concerns.
Methods: This study was conducted within a national, consumer-based medicines information service. Between September, 2002, and December, 2005, all calls relating to use of psychotropic medications in children and adolescents were identified and reviewed. Information extracted included call characteristics, reason for calling, prior information, and medication details. Calls related to safety were compared to calls about non-safety-related issues.
Results: A total …
Pharmacologic Responses Of The Mouse Urinary Bladder, A. Erdem, Christopher Chapple, Russ Chess-Williams
Pharmacologic Responses Of The Mouse Urinary Bladder, A. Erdem, Christopher Chapple, Russ Chess-Williams
Russ Chess-Williams
The aim of the study was to determine pathways involved in contraction and relaxation of the mouse urinary bladder. Mouse bladder strips were set up in gassed Krebs-bicarbonate solution and responses to various drugs and electrical field stimulation were obtained. Isoprenaline (b-receptor agonist) caused a 63% inhibition of carbachol precontracted detrusor (EC50=2nM). Carbachol caused contraction (EC50=0.3µM), responses were antagonised more potently by 4-DAMP (M3-antagonist) than methoctramine (M2-antagonist). Electrical field stimulation caused contraction, which was inhibited by atropine (60%) and less by guanethidine and α,β-methylene-ATP. The neurogenic responses were not potentiated by inhibition of nitric oxide synthase. Presence of an intact …
Pharmacologic Responses Of The Mouse Urinary Bladder, A. Erdem, Christopher Chapple, Russ Chess-Williams
Pharmacologic Responses Of The Mouse Urinary Bladder, A. Erdem, Christopher Chapple, Russ Chess-Williams
Russ Chess-Williams
The aim of the study was to determine pathways involved in contraction and relaxation of the mouse urinary bladder. Mouse bladder strips were set up in gassed Krebs-bicarbonate solution and responses to various drugs and electrical field stimulation were obtained. Isoprenaline (b-receptor agonist) caused a 63% inhibition of carbachol precontracted detrusor (EC50=2nM). Carbachol caused contraction (EC50=0.3µM), responses were antagonised more potently by 4-DAMP (M3-antagonist) than methoctramine (M2-antagonist). Electrical field stimulation caused contraction, which was inhibited by atropine (60%) and less by guanethidine and α,β-methylene-ATP. The neurogenic responses were not potentiated by inhibition of nitric oxide synthase. Presence of an intact …
A Law-Policy Proposal To Promote The Public Nature Of Science In An Era Of Academia-Industry Integration, Michael J. Malinowski
A Law-Policy Proposal To Promote The Public Nature Of Science In An Era Of Academia-Industry Integration, Michael J. Malinowski
Michael J. Malinowski
This article addresses the impact of integration of academia, industry, and government on the public nature of research. The article concludes that, while the integration has benefited science immensely, regulatory measures should be taken to restore the public nature of research in an age of integration.