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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Bioaccumulation Of As, Cd, Cr, Cu, Pb, Zn In Ambrosia Artemisiifolia L. In The Polluted Area By Enterprise For The Production And Processing Of Batteries, Ryzhenko Nataliia, El Amrani Abdelhak, Michelle Giltrap, Furong Tian, Volodymyr Laptev Jul 2022

Bioaccumulation Of As, Cd, Cr, Cu, Pb, Zn In Ambrosia Artemisiifolia L. In The Polluted Area By Enterprise For The Production And Processing Of Batteries, Ryzhenko Nataliia, El Amrani Abdelhak, Michelle Giltrap, Furong Tian, Volodymyr Laptev

Articles

In this paper, the concentration of As, Cd, Cr, Cu, Pb, Zn was investigated in soil and Ambrosia artemisiifolia L. sampling from polluted cite near the enterprises for the production and processing of batteries in the city of Dnipro in Ukraine. The obtained results of the study provided to assess plants regarding bio-monitoring and phytoremediation. Although Ambrosia artemisiifolia L. is a weed that causes serious allergic reactions in humans, this species can also have a high bioaccumulative capacity regarding metals. The metals’ concentration in roots was scientifically higher than in inflorescence part. Zn and Cu had the highest …


In Vitro Toxicological Evaluation Of Mesoporous Silica Microparticles Functionalised 1 With Carvacrol And Thymol, Cristina Fuentes, Ana Fuentes, Hugh Byrne, José Barat, María José Ruiz Feb 2022

In Vitro Toxicological Evaluation Of Mesoporous Silica Microparticles Functionalised 1 With Carvacrol And Thymol, Cristina Fuentes, Ana Fuentes, Hugh Byrne, José Barat, María José Ruiz

Articles

The cytotoxicity of carvacrol- and thymol- functionalised mesoporous silica microparticles (MCM-41) was assessed in the human hepatocarcinoma cell line (HepG2). Cell viability, lactate dehydrogenase (LDH) activity, reactive oxygen species (ROS) production, mitochondrial membrane potential (ΔΨm), lipid peroxidation (LPO) and apoptosis/necrosis analysis were used as endpoints. Results showed that both materials induced cytotoxicity in a time and concentration-dependent manner, being more cytotoxic than free essential oil components and bare MCM-41. This effect was caused by the cell-particle interactions and not from degradation products released to the culture media, as demonstrated in the extract dilution assays. LDH release was seen to be …