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Pharmacology, Toxicology and Environmental Health Commons

Open Access. Powered by Scholars. Published by Universities.®

Toxicology

Eastern Kentucky University

2022

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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Chromatographic Studies Of Some Hormone And Metabolic Modulators Used For Doping In Sports, Ruth Marie Speidel Jan 2022

Chromatographic Studies Of Some Hormone And Metabolic Modulators Used For Doping In Sports, Ruth Marie Speidel

Online Theses and Dissertations

The World Anti-Doping Agency (WADA) is an international agency that monitors the use of Performance Enhancing Drugs (PEDs) in sports; their mission is “to lead a collaborative worldwide movement for doping-free sport” (Who We Are, 2022). For this mission, the WADA needs quick, sensitive, reproducible, and accurate methods for analyzing athletes’ biological fluids for possible PEDs. This research focuses on developing and validating simple, sensitive, rapid, and reliable gas chromatography- mass spectrometry (GC-MS) methods for the analysis of two hormone and metabolic modulators, toremifene and trimetazidine. Previously, there has been limited GC-MS methods used to analyze toremifene and trimetazidine. Quantification …