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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Morphologic Comparisons Of Recrystallized And Neocrystallized Fibrous Amphibole Asbestos: Implications For Corresponding Health Risk Potential, Natalie G. Renkes May 2023

Morphologic Comparisons Of Recrystallized And Neocrystallized Fibrous Amphibole Asbestos: Implications For Corresponding Health Risk Potential, Natalie G. Renkes

UNLV Theses, Dissertations, Professional Papers, and Capstones

The presence of naturally-occurring asbestos (NOA) is increasingly concerning for scientists, health and regulatory agencies, and citizens living in impacted areas. It is commonly believed that fibrous amphibole asbestos can only form through neocrystallization. In southern Nevada, NOA occurs as a result of hydrothermal alteration of granitic rock producing fibrous amphibole both as cross-cutting neocrystallized veins and via recrystallization of original magmatic hornblende crystals. Fibers with a greater aspect ratio are known to have increased toxicity. This study measured the maximum length and average width of both neocrystallized and recrystallized fibers to see if the morphologies were similar. Neocrystallized and …


Pulmonary Immune Responses To Respirable Elongate Mineral Particles Of Asbestiform And Non-Asbestiform Morphologies, Timur Khaliullin Jan 2020

Pulmonary Immune Responses To Respirable Elongate Mineral Particles Of Asbestiform And Non-Asbestiform Morphologies, Timur Khaliullin

Graduate Theses, Dissertations, and Problem Reports

Inhalation exposure to asbestiform elongate mineral particles (EMPs) may cause pulmonary fibrosis, lung and pleural cancer. At the same time, epidemiological evidence for non-asbestiform EMP pathogenicity is scarce, with little if any risk of cancer, but consistent findings of pneumoconiosis and increased mortality. Globally, conditions caused by asbestos exposures contribute most to the occupational cancer burden and are responsible for the increasing mortality for occupational respiratory diseases. Immunological components of the fiber-induced lesions are extremely understudied, partly due to the lack of comparable test articles. In this study I utilized respirable preparations of asbestiform and non-asbestiform riebeckite and tremolite to …


Asbestos Risk Assessment In Pakistan: Current Scenario And Way Forward, Adeel Ahmed Khan, Asaad Ahmed Nafees, Zafar Fatmi Jan 2013

Asbestos Risk Assessment In Pakistan: Current Scenario And Way Forward, Adeel Ahmed Khan, Asaad Ahmed Nafees, Zafar Fatmi

Community Health Sciences

No abstract provided.


An Evaluation Of Potential Occupational Exposure To Asbestiform Amphiboles Near A Former Vermiculite Mine, Julie Hart, Terry Spear, Tony Ward, Caitlan Baldwin, Marissa Salo, Mohamed Elasheb Jan 2009

An Evaluation Of Potential Occupational Exposure To Asbestiform Amphiboles Near A Former Vermiculite Mine, Julie Hart, Terry Spear, Tony Ward, Caitlan Baldwin, Marissa Salo, Mohamed Elasheb

Safety Health & Industrial Hygiene

Amphibole asbestos (AA) has been detected on the surface of tree bark in forests neighboring an abandoned vermiculite mine near Libby, Montana. In the present study, simulations were performed to assess potential AA exposure associated with United States Department of Agriculture Forest Service (FS) occupational activities. Bark samples were collected prior, and personal breathing zone (PBZ) and Tyvek clothing wipe samples were collected during and immediately after trials that simulated FS activities. Transmission electron microscopy (TEM) analyses revealed AA bark concentrations up to 15 million structures per square centimeter (s/cm2). AA was detected in 25% of the PBZ TEM samples. …