Pharmacology, Toxicology and Environmental Health Commons^™

Aflatoxin-Exposure Of Vibrio Gazogenes As A Novel System For The Generation Of Aflatoxin Synthesis Inhibitors, Phani M. Gummadidala, Yung Pin Chen, Kevin R. Beauchesne, Kristen P. Miller, Chandrani Mitra, Michelle Velez-Martinez, Peter D. R. Moeller, John L. Ferry, Alan W. Decho, Anindya Chanda

Faculty Publications

Aflatoxin is a mycotoxin and a secondary metabolite, and the most potent known liver carcinogen that contaminates several important crops, and represents a significant threat to public health and the economy. Available approaches reported thus far have been insufficient to eliminate this threat, and therefore provide the rational to explore novel methods for preventing aflatoxin accumulation in the environment. Many terrestrial plants and microbes that share ecological niches and encounter the aflatoxin producers have the ability to synthesize compounds that inhibit aflatoxin synthesis. However, reports of natural aflatoxin inhibitors from marine ecosystem components that do not share ecological niches with …