Pharmacology, Toxicology and Environmental Health Commons^™

Computational Tools For Analyzing Correlations Between Microbial Biological Diversity And Ecosystems, Behzad Torkian

Theses and Dissertations

Metagenomics has developed into a reliable mechanism to analyze microbial diversity of microbial communities in the recent years. Through the use of next-generation sequencing, metagenomic studies can generate billions of short sequencing reads that are processed by computational tools. However, with the rapid adoption of metagenomics, a large amount of data has been produced. This high level of data production requires the development of computational tools and pipelines to manage data scalability and performance. In this thesis, we developed several tools that will aid in the exploration of the large amount of DNA sequence data, and we further developed a …