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Pharmacology, Toxicology and Environmental Health Commons™
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Articles 1 - 5 of 5
Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Roles Of Soil Pores In Determining Water Retention And Microbial Dynamics, Huihui Sun
Roles Of Soil Pores In Determining Water Retention And Microbial Dynamics, Huihui Sun
Doctoral Dissertations
Soil pore provides an essential habitat for microbial communities to participate in various biogeochemical processes. The complex pore spaces, which are defined by the arrangement of particles of varying sizes, govern the distribution of water for microbial dispersal and movement and microbial interaction with one another, such as bacterial cell-to-cell and bacterium-virus interactions. This research focused on exploring how soil pores influence soil water retention and bacterial interactions and quantify the spatial distribution of bacteria and viruses in fine-scale of soil pores. Using a mathematical model, this study simulated a soil water retention curve based on the relationship between soil …
Exploring Novel Environmental Link To Obesity: Role Of Parabens In Adipogenesis In Vitro And In Vivo, Pan Hu
Exploring Novel Environmental Link To Obesity: Role Of Parabens In Adipogenesis In Vitro And In Vivo, Pan Hu
Doctoral Dissertations
Parabens are a group of alkyl esters of p-hydroxybenzoic acid that include methylparaben, ethylparaben, propylparaben, butylparaben, and benzylparaben. Paraben esters and their salts are widely used as preservatives in cosmetics, toiletries, food, and pharmaceuticals. Humans are exposed to parabens through the use of such products from dermal contact, ingestion, and inhalation. The extent of the exposure is reflected by the frequent detection of these compounds in urine samples in the general population. Moreover, parabens have been detected in human serum, milk, placental tissues and breast tumor tissues. Parabens have been shown to preserve estrogenic/antiandrogenic effects, and can activate peroxisome proliferator-activated …
A Factor Analysis Of The Health, Safety, And Welfare In The Built Environment Toward Interior Design As Perceived By Building Industry Professionals, Dana Marie Moody
A Factor Analysis Of The Health, Safety, And Welfare In The Built Environment Toward Interior Design As Perceived By Building Industry Professionals, Dana Marie Moody
Doctoral Dissertations
This research study created, piloted, and field tested a new instrument designed to collect perceptions toward an interior designer’s impact on the health, safety, and welfare of the public. It also established an initial profile of perceptions within building industry professionals, identified the salient factors within those perceptions, and determined the level of these factors through a factor analysis. The Health, Safety, & Welfare in the Built Environment instrument was developed using a Table of Specifications based on the subject content that interior designers must be familiar with in regards to protecting the health, safety, and welfare of the public …
A Geospatial Based Decision Framework For Extending Marssim Regulatory Principles Into The Subsurface, Robert Nathan Stewart
A Geospatial Based Decision Framework For Extending Marssim Regulatory Principles Into The Subsurface, Robert Nathan Stewart
Doctoral Dissertations
The Multi-Agency Radiological Site Survey Investigation Manual (MARSSIM) is a regulatory guidance document regarding compliance evaluation of radiologically contaminated soils and buildings (USNRC, 2000). Compliance is determined by comparing radiological measurements to established limits using a combination of hypothesis testing and scanning measurements. Scanning allows investigators to identify localized pockets of contamination missed during sampling and allows investigators to assess radiological exposure at different spatial scales. Scale is important in radiological dose assessment as regulatory limits can vary with the size of the contaminated area and sites are often evaluated at more than one scale (USNRC, 2000). Unfortunately, scanning is …
Sublethal Toxicity Of Microcystis And Microcystin-Lr In Fish, Emily Dawn Rogers
Sublethal Toxicity Of Microcystis And Microcystin-Lr In Fish, Emily Dawn Rogers
Doctoral Dissertations
The occurrence of blooms of toxic cyanobacteria in freshwater environments is a global ecological and public health concern. Species of Microcystis are of particular importance because blooms occur in many freshwater environments throughout the world and microcystin toxin concentrations can exceed World Health Organization advisory levels. While microcystin has been associated with fish kills, sublethal effects of chronic exposure at environmentally relevant concentrations are relatively unknown. The objective of this research was to evaluate toxicity of microcystin and Microcystis in fish during all life history stages. We evaluated global gene expression response in larval zebrafish (Danio rerio), and …