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Pharmacology, Toxicology and Environmental Health Commons

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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Effects Of Bisphenol-S And Estrogen On P53 Expression In Ovarian Tissue Of Zebrafish (Danio Rerio), Jess Fairbanks Jan 2019

Effects Of Bisphenol-S And Estrogen On P53 Expression In Ovarian Tissue Of Zebrafish (Danio Rerio), Jess Fairbanks

Summer Research

Bisphenol A (BPA) is one the most widely used plasticizing compounds. As an endocrine disruptor, BPA could affect ovarian function and embryonic development. Bisphenol S (BPS) has been used in many plastics and resins in lieu of BPA. However, the effects of BPS are not widely known. Apoptosis is a type of genetically programmed cell death that is important in ovarian homeostasis. One of the genes that regulates apoptosis, p53, has been shown to respond to estrogen in maintaining ovarian homeostasis. We have investigated how exposure to estrogen and to BPS affects p53 expression in ovarian tissue in vitro …


Using Age To Assess Retention Time Of Ingested Plastic In Seabirds, Tessa G. Nania, Gary Shugart, Peter Hodum Jan 2018

Using Age To Assess Retention Time Of Ingested Plastic In Seabirds, Tessa G. Nania, Gary Shugart, Peter Hodum

Summer Research

For the past 30 years, plastic pollution research has used plastic ingested and retain in seabirds’ gastrointestinal (GIT) tract as indicators of pollution on different spatial and temporal scales. Types and size of plastic found in birds’ stomachs were used to determine pollution types and severity at different times and places. However, the length of time that birds can retain plastic in their GIT is unknown, making ingested plastic’s use as a bioindicator questionable. We assessed retention times in two seabird species, the Northern Fulmar (Fulmarus glacialis) and the Cassin’s Auklet (Ptychoramphus aleuticus), and compared the …


Northern Fulmars (Fulmarus Glacialis) As Bio-Indicators Of Endocrine Disrupting Plasticizers In The Marine Surface Environment., Olivia Feinstein Jan 2012

Northern Fulmars (Fulmarus Glacialis) As Bio-Indicators Of Endocrine Disrupting Plasticizers In The Marine Surface Environment., Olivia Feinstein

Summer Research

The plastics that make up over 10% of human waste are synthesized with phthalate plasticizers which are utilized in plastics as an additive to improve durability and flexibility. Many phthalates have been identified as endocrine disrupting chemicals (EDCs) and studies have shown dramatic deleterious effects as a result of species exposure to growing numbers of EDCs in the environment. Northern Fulmars (Fulmarus glacialis) are a northern hemisphere seabird species that forages opportunistically, meaning that they take advantage of a wide variety of different food sources, including inadvertent consumption of plastic. In addition to occupying space in the individuals’ …