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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Toxic Trace Elements In Follicular Fluid, Oxidative Stress, And In Vitro Fertilization (Ivf) Outcomes, Celeste Danielle Butts
Toxic Trace Elements In Follicular Fluid, Oxidative Stress, And In Vitro Fertilization (Ivf) Outcomes, Celeste Danielle Butts
Legacy Theses & Dissertations (2009 - 2024)
Exposures to environmental contaminants, including non-essential toxic trace elements, may be associated with in vitro fertilization (IVF) outcomes. Follicular fluid (FF) envelops the developing oocyte, offering a “snapshot” of the oocyte microenvironment. FF may better estimate trace element concentrations associated with IVF outcomes than more commonly employed blood and urine biomarkers of exposure. Hence, FF concentrations of four widespread non-essential toxic trace elements (arsenic, mercury, cadmium, and lead) were investigated in relation to a spectrum of IVF endpoints in n=56 women undergoing IVF. Antioxidant activity was explored as an intervening variable and dietary exposure sources of non-essential toxic trace elements …
Study Of Human Ovarian Follicular Fluid High Density Lipoprotein (Hdl) And Embryo Quality During In Vitro Fertilization (Ivf), Keewan Kim
Legacy Theses & Dissertations (2009 - 2024)
Follicular fluid (FF) is in direct contact with granulosa cells that surround a developing oocyte, and high density lipoprotein (HDL) is the sole lipoprotein found in FF. Therefore, we investigated 41 FF HDL particle components, including 26 HDL-cholesterol (HDL-C) subfractions measured for particle size, apolipoproteins, enzymes, and lipophilic micronutrients, in association with embryo quality on 180 women undergoing in vitro fertilization (IVF).
Seafood Consumption And Use Of Asian Herbal Preparation As A Source Of Exposure To Multiple Trace Elements In The Study Of Metals And Assisted Reproductive Technologies (Smart), Dongsul Kim
Legacy Theses & Dissertations (2009 - 2024)
As, Cd, Cs, Hg, Pb, and Zn may be associated with in vitro fertilization (IVF) outcomes. Seafood and Asian herbal preparations are identified as sources of exposure to these essential and non-essential trace elements in humans. The goal of the study is to assess associations between seafood consumption and the use of Asian herbal preparations and levels of essential and non-essential trace elements in biologic specimens collected from couples undergoing IVF. Fifty-nine couples completing a first IVF cycle at the University of California, San Francisco (UCSF) Center for Reproductive Health were recruited to participate in the Study of Metals and …