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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

A Review Of The Financial Value Of Faecal Sludge Reuse In Low-Income Countries, Adrian Mallory, Rochelle Holm, Alison Parker Oct 2020

A Review Of The Financial Value Of Faecal Sludge Reuse In Low-Income Countries, Adrian Mallory, Rochelle Holm, Alison Parker

Faculty Scholarship

Faecal sludge reuse could promote responsible waste management and alleviate resource shortages. However, for this reuse to be carried out at scale, it needs to be financially viable. This paper reviews the financial values of resource recovery from 112 data points from 43 publications from academic and grey literature. The results found 65% of the existing literature is projected rather than being based on observed data from products in practice, with limited studies providing actual experiences of revenue in practice. Some of the estimates of the potential value were ten times those observed in data from operating businesses. Reasons for …


Re-Evaluating The Strength Of Pit-Latrine Faecal Sludge From Dynamic Cone Penetrometer Test Data, Yasmine Shafiq, Stuart Haigh, Rochelle Holm, Alison Parker Oct 2020

Re-Evaluating The Strength Of Pit-Latrine Faecal Sludge From Dynamic Cone Penetrometer Test Data, Yasmine Shafiq, Stuart Haigh, Rochelle Holm, Alison Parker

Faculty Scholarship

In 2017, 55% of the global population were without safely managed sanitation services. On-site sanitation solutions, such as pit latrines, provide the majority of sanitation coverage across developing countries. Appropriate technologies are required in order to safely empty these latrines without damage to people or the environment. The design of appropriate emptying technologies can be hampered by a lack of knowledge of the mechanical properties of the waste, such as its strength. This paper will develop a calibration for a dynamic cone penetrometer to give accurate measurements of faecal sludge strength against a standard scale, rendering existing data comparable. It …


Volatile Organic Compound Exposure And Cardiometabolic Syndrome Risk In A Nationally Representative Cohort., Stacey Lane Konkle May 2020

Volatile Organic Compound Exposure And Cardiometabolic Syndrome Risk In A Nationally Representative Cohort., Stacey Lane Konkle

Electronic Theses and Dissertations

BACKGROUND: The relative importance of environmental exposures such as volatile organic compounds (VOCs) is one of the paramount public health priorities of our time, yet is presently unstudied. VOCs are ubiquitous in the environment and have been associated with numerous adverse health effects, including a number of cardiovascular and metabolic effects that are components of Cardiometabolic Syndrome (CMS). OBJECTIVES: To examine the relationship between CMS and individual-level exposures to VOCs, measured as urinary metabolites of VOCs (UM-VOCs), in a nationally representative sample. METHODS: Associations between urinary biomarkers of exposure to 19 parent VOCs and CMS were assessed using the National …


Tobacco Product-Derived Aldehydes: Effects On Circulating Angiogenic Cells & Implications For Cardiovascular Disease., Jordan B. Lynch May 2020

Tobacco Product-Derived Aldehydes: Effects On Circulating Angiogenic Cells & Implications For Cardiovascular Disease., Jordan B. Lynch

Electronic Theses and Dissertations

Cardiovascular disease (CVD) is the leading cause of death worldwide. Tobacco smoke is the most significant modifiable risk factor in CVD development and contains numerous toxic compounds, including aldehydes, which have been linked to CVD. Formaldehyde, acetaldehyde, acrolein, and crotonaldehyde have been identified as significant contributors to cigarette-induced health effects, but the mechanism of these effects is not well understood. These aldehydes are also found in aerosols produced by e-cigarettes (e-cigs). The goal of this dissertation was to explore the systemic, hematological, and endothelium-related effects of exposure to tobacco products and constituent aldehydes and to identify potential mechanisms of injury. …